Should abdomino-perineal resection be considered when a defunctioning stoma is required for anal canal squamous cell carcinoma?

Master Thesis

2014

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University of Cape Town

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Abstract
Combined modality treatment (CMT) is the preferred treatment for anal squamous cell carcinoma, but a small subgroup needs a defunctioning colostomy with temporary intent. The aim of this study was to evaluate the stoma closure rate of patients needing defunctioning colostomies prior to CMT for anal squamous cell carcinoma (SCC) at Groote Schuur Hospital (GSH). The key objective was to assess if abdomino-perineal resection (APR) should be offered as primary treatment modality for the subgroup of patients needing a defunctioning stoma and CMT.
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