Sensitisation to Blattella germanica among adults with asthma in Yaounde, Cameroon: a cross-sectional study

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dc.contributor.authorPefura-Yone, Ericen_ZA
dc.contributor.authorKengne, Andreen_ZA
dc.contributor.authorAfane-Ze, Emmanuelen_ZA
dc.contributor.authorKuaban, Christopheren_ZA
dc.date.accessioned2015-11-27T09:33:35Z
dc.date.available2015-11-27T09:33:35Z
dc.date.issued2014en_ZA
dc.description.abstractBACKGROUND: German cockroach or Blattella germanica is commonly found in homes across the inter-tropical region. The contribution of sensitisation to Blattella germanica in people with asthma in sub-Saharan Africa has not received attention. The aim of this study was to assess the prevalence and investigate the predicting factors of sensitisation to Blattella germanica in patients with asthma in Yaounde, Cameroon. METHODS: This was a cross-sectional study conducted between January 2012 and June 2013. All patients (aged 15years and above) with asthma, receiving care at the Yaounde Jamot Hospital and the CEDIMER medical practice during the study period and who had received a prick skin testing for perennial aeroallergens were included in the study. RESULTS: The final sample comprised 184 patients including 123 (66.8%) women. The median age (25th-75th percentiles) was 38 (24-54) years. Prick skin test for Blattella germanica was positive in 47 (25.5%) patients. Sensitisation to Blattella germanica was associated with a sensitisation to mite in 41 (87.2%) patients, a sensitisation to Alternaria in 18 (38.3%) patients, and a sensitisation to cat or dog dander in 7 (14.9%) patients. Independent predicting factors of a sensitisation to Blattella germanica were the sensitisation to Blomia tropicalis [adjusted odd ratio (95% confidence interval) 4.10 (1.67-10.04), p=0.002] and sensitisation to Alternaria [3.67 (1.53-7.46), p=0.003]. CONCLUSIONS: Sensitisation to Blattella germanica is present in about a quarter of adult patients with asthma in Yaounde. Sensitisation to Alternaria and Blomia tropicalis appears to be a powerful predicting factor of sensitisation to Blattella germanica in this setting.en_ZA
dc.identifier.apacitationPefura-Yone, E., Kengne, A., Afane-Ze, E., & Kuaban, C. (2014). Sensitisation to Blattella germanica among adults with asthma in Yaounde, Cameroon: a cross-sectional study. <i>World Allergy Organization Journal</i>, http://hdl.handle.net/11427/15395en_ZA
dc.identifier.chicagocitationPefura-Yone, Eric, Andre Kengne, Emmanuel Afane-Ze, and Christopher Kuaban "Sensitisation to Blattella germanica among adults with asthma in Yaounde, Cameroon: a cross-sectional study." <i>World Allergy Organization Journal</i> (2014) http://hdl.handle.net/11427/15395en_ZA
dc.identifier.citationPefura-Yone, E. W., Kengne, A. P., Afane-Ze, E., & Kuaban, C. (2014). Sensitisation to Blattella germanica among adults with asthma in Yaounde, Cameroon: a cross-sectional study. World Allergy Organization Journal, 7(1), 22.en_ZA
dc.identifier.ris TY - Journal Article AU - Pefura-Yone, Eric AU - Kengne, Andre AU - Afane-Ze, Emmanuel AU - Kuaban, Christopher AB - BACKGROUND: German cockroach or Blattella germanica is commonly found in homes across the inter-tropical region. The contribution of sensitisation to Blattella germanica in people with asthma in sub-Saharan Africa has not received attention. The aim of this study was to assess the prevalence and investigate the predicting factors of sensitisation to Blattella germanica in patients with asthma in Yaounde, Cameroon. METHODS: This was a cross-sectional study conducted between January 2012 and June 2013. All patients (aged 15years and above) with asthma, receiving care at the Yaounde Jamot Hospital and the CEDIMER medical practice during the study period and who had received a prick skin testing for perennial aeroallergens were included in the study. RESULTS: The final sample comprised 184 patients including 123 (66.8%) women. The median age (25th-75th percentiles) was 38 (24-54) years. Prick skin test for Blattella germanica was positive in 47 (25.5%) patients. Sensitisation to Blattella germanica was associated with a sensitisation to mite in 41 (87.2%) patients, a sensitisation to Alternaria in 18 (38.3%) patients, and a sensitisation to cat or dog dander in 7 (14.9%) patients. Independent predicting factors of a sensitisation to Blattella germanica were the sensitisation to Blomia tropicalis [adjusted odd ratio (95% confidence interval) 4.10 (1.67-10.04), p=0.002] and sensitisation to Alternaria [3.67 (1.53-7.46), p=0.003]. CONCLUSIONS: Sensitisation to Blattella germanica is present in about a quarter of adult patients with asthma in Yaounde. Sensitisation to Alternaria and Blomia tropicalis appears to be a powerful predicting factor of sensitisation to Blattella germanica in this setting. DA - 2014 DB - OpenUCT DO - 10.1186/1939-4551-7-22 DP - University of Cape Town J1 - World Allergy Organization Journal LK - https://open.uct.ac.za PB - University of Cape Town PY - 2014 T1 - Sensitisation to Blattella germanica among adults with asthma in Yaounde, Cameroon: a cross-sectional study TI - Sensitisation to Blattella germanica among adults with asthma in Yaounde, Cameroon: a cross-sectional study UR - http://hdl.handle.net/11427/15395 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/15395
dc.identifier.urihttp://dx.doi.org/10.1186/1939-4551-7-22
dc.identifier.vancouvercitationPefura-Yone E, Kengne A, Afane-Ze E, Kuaban C. Sensitisation to Blattella germanica among adults with asthma in Yaounde, Cameroon: a cross-sectional study. World Allergy Organization Journal. 2014; http://hdl.handle.net/11427/15395.en_ZA
dc.language.isoengen_ZA
dc.publisherBioMed Central Ltden_ZA
dc.publisher.departmentDepartment of Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Licenseen_ZA
dc.rights.holder2014 Pefura-Yone et al.; licensee BioMed Central Ltd.en_ZA
dc.rights.urihttp://creativecommons.org/licenses/by/2.0en_ZA
dc.sourceWorld Allergy Organization Journalen_ZA
dc.source.urihttp://www.waojournal.org/en_ZA
dc.subject.otherAsthmaen_ZA
dc.subject.otherBlattellaen_ZA
dc.subject.otherAllergyen_ZA
dc.subject.otherAeroallergensen_ZA
dc.subject.otherAfricaen_ZA
dc.titleSensitisation to Blattella germanica among adults with asthma in Yaounde, Cameroon: a cross-sectional studyen_ZA
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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