South African guideline for the management of chronic hepatitis B: 2013

Simple item page
dc.contributor.authorSpearman, C W N
dc.contributor.authorSonderup, Mark W
dc.contributor.authorBotha, J F
dc.contributor.authorvan der Merwe, S W
dc.contributor.authorSong, E
dc.contributor.authorKassianides, C
dc.contributor.authorNewton, K A
dc.contributor.authorHairwadzi, H N
dc.date.accessioned2021-10-08T07:20:26Z
dc.date.available2021-10-08T07:20:26Z
dc.date.issued2013
dc.description.abstractHepatitis B remains a significant yet preventable health issue in South Africa. The introduction of the hepatitis B vaccine into the country some 18 years ago has demonstrated benefit, but the exposure to, and prevalence of chronic HBsAg positivity remain unacceptably high. Those with chronic hepatitis B virus infection have an elevated risk of developing cirrhosis with end-stage liver disease and a markedly elevated risk of hepatocellular carcinoma, independent of the presence of cirrhosis. The challenge in South Africa remains prevention through the universal vaccination coverage of all children and the identification of those with chronic hepatitis B virus infection. Over the last decade our understanding of hepatitis B and its behaviour and natural history in those with chronic infection has significantly improved. This understanding is key to identifying those who warrant further evaluation and therapy. A number of global societies have updated their guidelines in recent years. This document draws on these guidelines and serves to contextualise, for South Africa, practice guidelines for the management of chronic hepatitis B.
dc.identifier.apacitationSpearman, C. W. N., Sonderup, M. W., Botha, J. F., van der Merwe, S. W., Song, E., Kassianides, C., ... Hairwadzi, H. N. (2013). South African guideline for the management of chronic hepatitis B: 2013. <i>South African Medical Journal</i>, 103(5), 335 - 177. http://hdl.handle.net/11427/34912en_ZA
dc.identifier.chicagocitationSpearman, C W N, Mark W Sonderup, J F Botha, S W van der Merwe, E Song, C Kassianides, K A Newton, and H N Hairwadzi "South African guideline for the management of chronic hepatitis B: 2013." <i>South African Medical Journal</i> 103, 5. (2013): 335 - 177. http://hdl.handle.net/11427/34912en_ZA
dc.identifier.citationSpearman, C.W.N., Sonderup, M.W., Botha, J.F., van der Merwe, S.W., Song, E., Kassianides, C., Newton, K.A. & Hairwadzi, H.N. et al. 2013. South African guideline for the management of chronic hepatitis B: 2013. <i>South African Medical Journal.</i> 103(5):335 - 177. http://hdl.handle.net/11427/34912en_ZA
dc.identifier.issn0038-2469
dc.identifier.ris TY - Journal Article AU - Spearman, C W N AU - Sonderup, Mark W AU - Botha, J F AU - van der Merwe, S W AU - Song, E AU - Kassianides, C AU - Newton, K A AU - Hairwadzi, H N AB - Hepatitis B remains a significant yet preventable health issue in South Africa. The introduction of the hepatitis B vaccine into the country some 18 years ago has demonstrated benefit, but the exposure to, and prevalence of chronic HBsAg positivity remain unacceptably high. Those with chronic hepatitis B virus infection have an elevated risk of developing cirrhosis with end-stage liver disease and a markedly elevated risk of hepatocellular carcinoma, independent of the presence of cirrhosis. The challenge in South Africa remains prevention through the universal vaccination coverage of all children and the identification of those with chronic hepatitis B virus infection. Over the last decade our understanding of hepatitis B and its behaviour and natural history in those with chronic infection has significantly improved. This understanding is key to identifying those who warrant further evaluation and therapy. A number of global societies have updated their guidelines in recent years. This document draws on these guidelines and serves to contextualise, for South Africa, practice guidelines for the management of chronic hepatitis B. DA - 2013 DB - OpenUCT DP - University of Cape Town IS - 5 J1 - South African Medical Journal LK - https://open.uct.ac.za PY - 2013 SM - 0038-2469 T1 - South African guideline for the management of chronic hepatitis B: 2013 TI - South African guideline for the management of chronic hepatitis B: 2013 UR - http://hdl.handle.net/11427/34912 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/34912
dc.identifier.vancouvercitationSpearman CWN, Sonderup MW, Botha JF, van der Merwe SW, Song E, Kassianides C, et al. South African guideline for the management of chronic hepatitis B: 2013. South African Medical Journal. 2013;103(5):335 - 177. http://hdl.handle.net/11427/34912.en_ZA
dc.language.isoeng
dc.publisher.departmentDivision of Hepatology
dc.publisher.facultyFaculty of Health Sciences
dc.sourceSouth African Medical Journal
dc.source.journalissue5
dc.source.journalvolume103
dc.source.pagination335 - 177
dc.source.urihttps://dx.doi.org/10.7196/SAMJ.6452
dc.subject.otherAdult
dc.subject.otherAntiviral Agents
dc.subject.otherChild
dc.subject.otherDrug Monitoring
dc.subject.otherHepatitis B Antibodies
dc.subject.otherHepatitis B Antigens
dc.subject.otherHepatitis B virus
dc.subject.otherHepatitis B, Chronic
dc.subject.otherHumans
dc.subject.otherLiver Cirrhosis
dc.subject.otherLiver Neoplasms
dc.subject.otherMedication Therapy Management
dc.subject.otherSouth Africa
dc.titleSouth African guideline for the management of chronic hepatitis B: 2013
dc.typeJournal Article
uct.type.publicationResearch
uct.type.resourceJournal Article
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
SpearmanCWN_South_African_g_2013.pdf
Size:
281.19 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Journal Articles