A prime-boost immunization with rBCG expressing HIV-1 Gag, RT and gp120 and SAAVI MVA-C elicits immune responses in blood and MALT of rhesus macaques

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dc.contributor.authorChege, GKen_ZA
dc.contributor.authorChapman, Ren_ZA
dc.contributor.authorShephard, EGen_ZA
dc.contributor.authorWilliamson, Aen_ZA
dc.date.accessioned2015-11-18T03:47:00Z
dc.date.available2015-11-18T03:47:00Z
dc.date.issued2012en_ZA
dc.description.abstractCG pantothenate auxtroph (ΔpanCD) is safer to use as a live vaccine vector than wild-type BCG. We constructed 3 recombinant BCGΔpanCD candidate vaccines expressing HIV-1 subtype C Gag, RT and Env (gp120). The current study investigated immune responses in rhesus macaques following a prime with a mixture of these rBCG vaccines and a boost with SAAVI MVA-C (MVA).en_ZA
dc.identifier.apacitationChege, G., Chapman, R., Shephard, E., & Williamson, A. (2012). A prime-boost immunization with rBCG expressing HIV-1 Gag, RT and gp120 and SAAVI MVA-C elicits immune responses in blood and MALT of rhesus macaques. <i>Retrovirology</i>, http://hdl.handle.net/11427/15047en_ZA
dc.identifier.chicagocitationChege, GK, R Chapman, EG Shephard, and A Williamson "A prime-boost immunization with rBCG expressing HIV-1 Gag, RT and gp120 and SAAVI MVA-C elicits immune responses in blood and MALT of rhesus macaques." <i>Retrovirology</i> (2012) http://hdl.handle.net/11427/15047en_ZA
dc.identifier.citationChege, G. K., Chapman, R., Shephard, E. G., & Williamson, A. (2012). A prime-boost immunization with rBCG expressing HIV-1 Gag, RT and gp120 and SAAVI MVA-C elicits immune responses in blood and MALT of rhesus macaques. Retrovirology, 9(Suppl 2), P40.en_ZA
dc.identifier.ris TY - Journal Article AU - Chege, GK AU - Chapman, R AU - Shephard, EG AU - Williamson, A AB - CG pantothenate auxtroph (ΔpanCD) is safer to use as a live vaccine vector than wild-type BCG. We constructed 3 recombinant BCGΔpanCD candidate vaccines expressing HIV-1 subtype C Gag, RT and Env (gp120). The current study investigated immune responses in rhesus macaques following a prime with a mixture of these rBCG vaccines and a boost with SAAVI MVA-C (MVA). DA - 2012 DB - OpenUCT DO - 10.1186/1742-4690-9-S2-P40 DP - University of Cape Town J1 - Retrovirology LK - https://open.uct.ac.za PB - University of Cape Town PY - 2012 T1 - A prime-boost immunization with rBCG expressing HIV-1 Gag, RT and gp120 and SAAVI MVA-C elicits immune responses in blood and MALT of rhesus macaques TI - A prime-boost immunization with rBCG expressing HIV-1 Gag, RT and gp120 and SAAVI MVA-C elicits immune responses in blood and MALT of rhesus macaques UR - http://hdl.handle.net/11427/15047 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/15047
dc.identifier.urihttp://dx.doi.org/10.1186/1742-4690-9-S2-P40
dc.identifier.vancouvercitationChege G, Chapman R, Shephard E, Williamson A. A prime-boost immunization with rBCG expressing HIV-1 Gag, RT and gp120 and SAAVI MVA-C elicits immune responses in blood and MALT of rhesus macaques. Retrovirology. 2012; http://hdl.handle.net/11427/15047.en_ZA
dc.language.isoengen_ZA
dc.publisherBioMed Central Ltden_ZA
dc.publisher.departmentDivision of Virologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Licenseen_ZA
dc.rights.holder2012 Chege et al; licensee BioMed Central Ltd.en_ZA
dc.rights.urihttp://creativecommons.org/licenses/by/2.0en_ZA
dc.sourceRetrovirologyen_ZA
dc.source.urihttp://www.retrovirology.com/en_ZA
dc.subject.otherHIV-1 Peptideen_ZA
dc.subject.otherHIV-1 Subtypeen_ZA
dc.subject.otherrBCG Vaccineen_ZA
dc.subject.othervaccine-specific Immune Responseen_ZA
dc.titleA prime-boost immunization with rBCG expressing HIV-1 Gag, RT and gp120 and SAAVI MVA-C elicits immune responses in blood and MALT of rhesus macaquesen_ZA
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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