On prioritising global health’s triple crisis of sepsis, COVID-19 and antimicrobial resistance: a mixed-methods study from Malawi

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dc.contributor.authorKawale, Paul
dc.contributor.authorKalitsilo, Levi
dc.contributor.authorMphande, Jessie
dc.contributor.authorRomeo Adegbite, Bayode
dc.contributor.authorGrobusch, Martin P
dc.contributor.authorJacob, Shevin T
dc.contributor.authorRylance, Jamie
dc.contributor.authorMadise, Nyovani J
dc.date.accessioned2022-07-08T07:39:17Z
dc.date.available2022-07-08T07:39:17Z
dc.date.issued2022-05-07
dc.date.updated2022-05-08T03:25:10Z
dc.description.abstractSepsis causes 20% of global deaths, particularly among children and vulnerable populations living in developing countries. This study investigated how sepsis is prioritised in Malawi’s health system to inform health policy. In this mixed-methods study, twenty multisectoral stakeholders were qualitatively interviewed and asked to quantitatively rate the likelihood of sepsis-related medium-term policy outcomes being realised. Respondents indicated that sepsis is not prioritised in Malawi due to a lack of local sepsis-related evidence and policies. However, they highlighted strong linkages between sepsis and maternal health, antimicrobial resistance and COVID-19, which are already existing national priorities, and offers opportunities for sepsis researchers as policy entrepreneurs. To address the burden of sepsis, we recommend that funding should be channelled to the generation of local evidence, evidence uptake, procurement of resources and treatment of sepsis cases, development of appropriate indicators for sepsis, adherence to infection prevention and control measures, and antimicrobial stewardship.en_US
dc.identifier.apacitationKawale, P., Kalitsilo, L., Mphande, J., Romeo Adegbite, B., Grobusch, M. P., Jacob, S. T., ... Madise, N. J. (2022). On prioritising global health’s triple crisis of sepsis, COVID-19 and antimicrobial resistance: a mixed-methods study from Malawi. <i>BMC Health Services Research</i>, 22(1), 613. http://hdl.handle.net/11427/36633en_ZA
dc.identifier.chicagocitationKawale, Paul, Levi Kalitsilo, Jessie Mphande, Bayode Romeo Adegbite, Martin P Grobusch, Shevin T Jacob, Jamie Rylance, and Nyovani J Madise "On prioritising global health’s triple crisis of sepsis, COVID-19 and antimicrobial resistance: a mixed-methods study from Malawi." <i>BMC Health Services Research</i> 22, 1. (2022): 613. http://hdl.handle.net/11427/36633en_ZA
dc.identifier.citationKawale, P., Kalitsilo, L., Mphande, J., Romeo Adegbite, B., Grobusch, M.P., Jacob, S.T., Rylance, J. & Madise, N.J. et al. 2022. On prioritising global health’s triple crisis of sepsis, COVID-19 and antimicrobial resistance: a mixed-methods study from Malawi. <i>BMC Health Services Research.</i> 22(1):613. http://hdl.handle.net/11427/36633en_ZA
dc.identifier.ris TY - Journal Article AU - Kawale, Paul AU - Kalitsilo, Levi AU - Mphande, Jessie AU - Romeo Adegbite, Bayode AU - Grobusch, Martin P AU - Jacob, Shevin T AU - Rylance, Jamie AU - Madise, Nyovani J AB - Sepsis causes 20% of global deaths, particularly among children and vulnerable populations living in developing countries. This study investigated how sepsis is prioritised in Malawi’s health system to inform health policy. In this mixed-methods study, twenty multisectoral stakeholders were qualitatively interviewed and asked to quantitatively rate the likelihood of sepsis-related medium-term policy outcomes being realised. Respondents indicated that sepsis is not prioritised in Malawi due to a lack of local sepsis-related evidence and policies. However, they highlighted strong linkages between sepsis and maternal health, antimicrobial resistance and COVID-19, which are already existing national priorities, and offers opportunities for sepsis researchers as policy entrepreneurs. To address the burden of sepsis, we recommend that funding should be channelled to the generation of local evidence, evidence uptake, procurement of resources and treatment of sepsis cases, development of appropriate indicators for sepsis, adherence to infection prevention and control measures, and antimicrobial stewardship. DA - 2022-05-07 DB - OpenUCT DP - University of Cape Town IS - 1 J1 - BMC Health Services Research KW - Sepsis KW - Health system KW - Health priority KW - Antimicrobial resistance KW - COVID-19 LK - https://open.uct.ac.za PY - 2022 T1 - On prioritising global health’s triple crisis of sepsis, COVID-19 and antimicrobial resistance: a mixed-methods study from Malawi TI - On prioritising global health’s triple crisis of sepsis, COVID-19 and antimicrobial resistance: a mixed-methods study from Malawi UR - http://hdl.handle.net/11427/36633 ER - en_ZA
dc.identifier.urihttps://doi.org/10.1186/s12913-022-08007-0
dc.identifier.urihttp://hdl.handle.net/11427/36633
dc.identifier.vancouvercitationKawale P, Kalitsilo L, Mphande J, Romeo Adegbite B, Grobusch MP, Jacob ST, et al. On prioritising global health’s triple crisis of sepsis, COVID-19 and antimicrobial resistance: a mixed-methods study from Malawi. BMC Health Services Research. 2022;22(1):613. http://hdl.handle.net/11427/36633.en_ZA
dc.language.rfc3066en
dc.publisher.departmentInstitute of Infectious Disease and Molecular Medicineen_US
dc.publisher.facultyFaculty of Health Sciencesen_US
dc.rightsCreative Commons Attribute 4.0 International
dc.rights.holderThe Author(s)
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_US
dc.sourceBMC Health Services Researchen_US
dc.source.journalissue1en_US
dc.source.journalvolume22en_US
dc.source.pagination613en_US
dc.source.urihttps://bmchealthservres.biomedcentral.com/
dc.subjectSepsisen_US
dc.subjectHealth systemen_US
dc.subjectHealth priorityen_US
dc.subjectAntimicrobial resistanceen_US
dc.subjectCOVID-19en_US
dc.titleOn prioritising global health’s triple crisis of sepsis, COVID-19 and antimicrobial resistance: a mixed-methods study from Malawien_US
dc.typeJournal Articleen_US
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