Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa

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dc.contributor.authorAdeola, Henry A
dc.contributor.authorSoyele, Olujide O
dc.contributor.authorAdefuye, Anthonio O
dc.contributor.authorJimoh, Sikiru A
dc.contributor.authorButali, Azeez
dc.date.accessioned2017-06-13T06:36:30Z
dc.date.available2017-06-13T06:36:30Z
dc.date.issued2017-06-05
dc.date.updated2017-06-11T03:14:53Z
dc.description.abstractBackground: The completion of the human genome project and the accomplished milestones in the human proteome project; as well as the progress made so far in computational bioinformatics and “big data” processing have contributed immensely to individualized/personalized medicine in the developed world. Main body: At the dawn of precision medicine, various omics-based therapies and bioengineering can now be applied accurately for the diagnosis, prognosis, treatment, and risk stratifcation of cancer in a manner that was hitherto not thought possible. The widespread introduction of genomics and other omics-based approaches into the postgraduate training curriculum of diverse medical and dental specialties, including pathology has improved the profciency of practitioners in the use of novel molecular signatures in patient management. In addition, intricate details about disease disparity among diferent human populations are beginning to emerge. This would facilitate the use of tailor-made novel theranostic methods based on emerging molecular evidences. Conclusion: In this review, we examined the challenges and prospects of using currently available omics-based technologies vis-à-vis oral pathology as well as prompt cancer diagnosis and treatment in a resource limited setting.
dc.identifier.apacitationAdeola, H. A., Soyele, O. O., Adefuye, A. O., Jimoh, S. A., & Butali, A. (2017). Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa. <i>Cancer Cell International</i>, http://hdl.handle.net/11427/24565en_ZA
dc.identifier.chicagocitationAdeola, Henry A, Olujide O Soyele, Anthonio O Adefuye, Sikiru A Jimoh, and Azeez Butali "Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa." <i>Cancer Cell International</i> (2017) http://hdl.handle.net/11427/24565en_ZA
dc.identifier.citationAdeola, H. A., Soyele, O. O., Adefuye, A. O., Jimoh, S. A., & Butali, A. (2017). Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa. Cancer Cell International, 17(1), 61.
dc.identifier.ris TY - Journal Article AU - Adeola, Henry A AU - Soyele, Olujide O AU - Adefuye, Anthonio O AU - Jimoh, Sikiru A AU - Butali, Azeez AB - Background: The completion of the human genome project and the accomplished milestones in the human proteome project; as well as the progress made so far in computational bioinformatics and “big data” processing have contributed immensely to individualized/personalized medicine in the developed world. Main body: At the dawn of precision medicine, various omics-based therapies and bioengineering can now be applied accurately for the diagnosis, prognosis, treatment, and risk stratifcation of cancer in a manner that was hitherto not thought possible. The widespread introduction of genomics and other omics-based approaches into the postgraduate training curriculum of diverse medical and dental specialties, including pathology has improved the profciency of practitioners in the use of novel molecular signatures in patient management. In addition, intricate details about disease disparity among diferent human populations are beginning to emerge. This would facilitate the use of tailor-made novel theranostic methods based on emerging molecular evidences. Conclusion: In this review, we examined the challenges and prospects of using currently available omics-based technologies vis-à-vis oral pathology as well as prompt cancer diagnosis and treatment in a resource limited setting. DA - 2017-06-05 DB - OpenUCT DO - 10.1186/s12935-017-0432-8 DP - University of Cape Town J1 - Cancer Cell International LK - https://open.uct.ac.za PB - University of Cape Town PY - 2017 T1 - Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa TI - Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa UR - http://hdl.handle.net/11427/24565 ER - en_ZA
dc.identifier.urihttp://dx.doi.org/10.1186/s12935-017-0432-8
dc.identifier.urihttp://hdl.handle.net/11427/24565
dc.identifier.vancouvercitationAdeola HA, Soyele OO, Adefuye AO, Jimoh SA, Butali A. Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa. Cancer Cell International. 2017; http://hdl.handle.net/11427/24565.en_ZA
dc.language.isoen
dc.publisherBioMed Central
dc.publisher.departmentDivision of Dermatologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rights.holderThe Author(s)
dc.sourceCancer Cell International
dc.source.urihttps://cancerci.biomedcentral.com/
dc.subject.otherOmics-based
dc.subject.otherMolecular
dc.subject.otherDeveloping world
dc.subject.otherOral pathology
dc.subject.otherChallenges
dc.titleOmics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa
dc.typeJournal Article
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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