An immunohistochemical assessment of endomyocardial biopsy specimens from the South African arrhythmogenic right ventricular cardiomyopathy registry

Master Thesis

2014

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http://hdl.handle.net/11427/13236
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thesis_hsf_2014_morse_n.pdf (1.22 MB)
Authors
Morse, Nicole
Supervisors
Wainwright, Helen
Mayosi, Bongani
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University of Cape Town

Department
Division of Anatomical Pathology
Faculty
Faculty of Health Sciences
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Abstract
Arrhythmogenic right ventricular cardiomyopathy / dysplasia (ARVC/D) is a genetic disease causing fibro-fatty replacement of the right ventricular myocardium, resulting in cardiac arrhythmias and sudden death. Part of the diagnostic work up for these patients includes a biopsy of the endocardium which has historically been difficult to interpret and of limited value in the early stages of disease. This study will focus on novel immunohistochemical stains of the cardiac desmosomes. These will be used to try to aid in the early diagnosis of ARVC.
Description

Includes bibliographical references.

Keywords
Anatomical Pathology

Reference:

Morse, N. 2014. An immunohistochemical assessment of endomyocardial biopsy specimens from the South African arrhythmogenic right ventricular cardiomyopathy registry. University of Cape Town.

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Masters