Exploring the cardioprotective effect of synthetic wine in Long Evans rats

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dc.contributor.advisorLecour, Sandrineen_ZA
dc.contributor.advisorBlackurst, Deeen_ZA
dc.contributor.authorDlamini, Lindizween_ZA
dc.date.accessioned2015-12-10T09:33:39Z
dc.date.available2015-12-10T09:33:39Z
dc.date.issued2015en_ZA
dc.description.abstract[No copyright notice] Background: Moderate and chronic consumption of red wine protects against cardiovascular disease. Wine is a complex matrix containing multiple molecules whose concentrations can vary from one bottle to another. Therefore, the delineation of the putative cardioprotective components in wine such as alcohol, resveratrol and melatonin is very challenging when using commercially available red wine. Aim: We aimed to use synthetic wine, whose composition is well characterized, to explore whether the presence of alcohol, resveratrol and melatonin (as found in commercial wines) contributes to the cardioprotective effect of chronic and moderate consumption of red wine (equivalent to 2 glasses of wine/day) in an animal model. Additionally, we hypothesized that synthetic wine enriched with resveratrol and melatonin confers cardioprotection via improvement of overall antioxidant profile.en_ZA
dc.identifier.apacitationDlamini, L. (2015). <i>Exploring the cardioprotective effect of synthetic wine in Long Evans rats</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Medicine. Retrieved from http://hdl.handle.net/11427/15763en_ZA
dc.identifier.chicagocitationDlamini, Lindizwe. <i>"Exploring the cardioprotective effect of synthetic wine in Long Evans rats."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2015. http://hdl.handle.net/11427/15763en_ZA
dc.identifier.citationDlamini, L. 2015. Exploring the cardioprotective effect of synthetic wine in Long Evans rats. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Dlamini, Lindizwe AB - [No copyright notice] Background: Moderate and chronic consumption of red wine protects against cardiovascular disease. Wine is a complex matrix containing multiple molecules whose concentrations can vary from one bottle to another. Therefore, the delineation of the putative cardioprotective components in wine such as alcohol, resveratrol and melatonin is very challenging when using commercially available red wine. Aim: We aimed to use synthetic wine, whose composition is well characterized, to explore whether the presence of alcohol, resveratrol and melatonin (as found in commercial wines) contributes to the cardioprotective effect of chronic and moderate consumption of red wine (equivalent to 2 glasses of wine/day) in an animal model. Additionally, we hypothesized that synthetic wine enriched with resveratrol and melatonin confers cardioprotection via improvement of overall antioxidant profile. DA - 2015 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2015 T1 - Exploring the cardioprotective effect of synthetic wine in Long Evans rats TI - Exploring the cardioprotective effect of synthetic wine in Long Evans rats UR - http://hdl.handle.net/11427/15763 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/15763
dc.identifier.vancouvercitationDlamini L. Exploring the cardioprotective effect of synthetic wine in Long Evans rats. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2015 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/15763en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherSubmitted for the Degree of Master of Science in Medicineen_ZA
dc.titleExploring the cardioprotective effect of synthetic wine in Long Evans ratsen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMSc (Med)en_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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