Dietary lipid modification for mild and severe dyslipidaemias

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dc.contributor.authorMarais, A David
dc.date.accessioned2021-10-08T07:22:55Z
dc.date.available2021-10-08T07:22:55Z
dc.date.issued2013
dc.description.abstractThe aim of this review is to place a historical perspective on linking dyslipidaemia with atherosclerosis and emphasises previous knowledge about the impact on the lipoprotein profile and health in persons with mild dyslipidaemia and in those with defined genetic disorders. CVD is becoming the leading cause of death and disability in developed and developing countries and is strongly related to lifestyle factors that influence plasma lipoprotein concentrations. It is established that risk of complications from atherosclerosis increases with increasing LDL and decreasing HDL and that there is potentiation of risk when these and other risk factors co-exist. High-fat diets used for losing body mass may increase risk through dyslipidaemia. Pharmaceutical modulation of the lipoproteins has lowered risk powerfully but residual risk persists, possibly relating to existing disease as well as progression relating in many instances to dietary lipids. The impact of various dietary lipids is reviewed as they relate to the conventional lipoprotein profile in persons who do not have significant metabolic defects, as well as the impact on inherited metabolic disease such as familial hypercholesterolaemia, hypertriglyceridaemia and phytosterolaemia. For most persons with dyslipidaemias a significant benefit will be seen on the lipid profile by adopting a low saturated fat diet with less cholesterol intake.
dc.identifier.apacitationMarais, A. D. (2013). Dietary lipid modification for mild and severe dyslipidaemias. <i>The Proceedings of the Nutrition Society</i>, 72(3), 337 - 341. http://hdl.handle.net/11427/35027en_ZA
dc.identifier.chicagocitationMarais, A David "Dietary lipid modification for mild and severe dyslipidaemias." <i>The Proceedings of the Nutrition Society</i> 72, 3. (2013): 337 - 341. http://hdl.handle.net/11427/35027en_ZA
dc.identifier.citationMarais, A.D. 2013. Dietary lipid modification for mild and severe dyslipidaemias. <i>The Proceedings of the Nutrition Society.</i> 72(3):337 - 341. http://hdl.handle.net/11427/35027en_ZA
dc.identifier.issn0029-6651
dc.identifier.issn1475-2719
dc.identifier.ris TY - Journal Article AU - Marais, A David AB - The aim of this review is to place a historical perspective on linking dyslipidaemia with atherosclerosis and emphasises previous knowledge about the impact on the lipoprotein profile and health in persons with mild dyslipidaemia and in those with defined genetic disorders. CVD is becoming the leading cause of death and disability in developed and developing countries and is strongly related to lifestyle factors that influence plasma lipoprotein concentrations. It is established that risk of complications from atherosclerosis increases with increasing LDL and decreasing HDL and that there is potentiation of risk when these and other risk factors co-exist. High-fat diets used for losing body mass may increase risk through dyslipidaemia. Pharmaceutical modulation of the lipoproteins has lowered risk powerfully but residual risk persists, possibly relating to existing disease as well as progression relating in many instances to dietary lipids. The impact of various dietary lipids is reviewed as they relate to the conventional lipoprotein profile in persons who do not have significant metabolic defects, as well as the impact on inherited metabolic disease such as familial hypercholesterolaemia, hypertriglyceridaemia and phytosterolaemia. For most persons with dyslipidaemias a significant benefit will be seen on the lipid profile by adopting a low saturated fat diet with less cholesterol intake. DA - 2013 DB - OpenUCT DP - University of Cape Town IS - 3 J1 - The Proceedings of the Nutrition Society LK - https://open.uct.ac.za PY - 2013 SM - 0029-6651 SM - 1475-2719 T1 - Dietary lipid modification for mild and severe dyslipidaemias TI - Dietary lipid modification for mild and severe dyslipidaemias UR - http://hdl.handle.net/11427/35027 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/35027
dc.identifier.vancouvercitationMarais AD. Dietary lipid modification for mild and severe dyslipidaemias. The Proceedings of the Nutrition Society. 2013;72(3):337 - 341. http://hdl.handle.net/11427/35027.en_ZA
dc.language.isoeng
dc.publisher.departmentDivision of Chemical Pathology
dc.publisher.facultyFaculty of Health Sciences
dc.sourceThe Proceedings of the Nutrition Society
dc.source.journalissue3
dc.source.journalvolume72
dc.source.pagination337 - 341
dc.source.urihttps://dx.doi.org/10.1017/S0029665113001298
dc.subject.otherAtherosclerosis
dc.subject.otherCholesterol, HDL
dc.subject.otherCholesterol, LDL
dc.subject.otherDietary Fats
dc.subject.otherDyslipidemias
dc.subject.otherHumans
dc.subject.otherLipid Metabolism
dc.subject.otherCholesterol, HDL
dc.subject.otherCholesterol, LDL
dc.subject.otherDietary Fats
dc.titleDietary lipid modification for mild and severe dyslipidaemias
dc.typeJournal Article
uct.type.publicationResearch
uct.type.resourceJournal Article
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