The association of the secondary DNA-binding site of linker histone H5 in a nucleosome
| dc.contributor.advisor | Patterton, Hugh | en_ZA |
| dc.contributor.author | Koorsen, Gerrit | en_ZA |
| dc.date.accessioned | 2014-07-30T17:38:43Z | |
| dc.date.available | 2014-07-30T17:38:43Z | |
| dc.date.issued | 2001 | en_ZA |
| dc.description | Bibliography: leaves 153-170. | |
| dc.description.abstract | In order to understand the role of linker histones in the formation of the 30-run chromatin fibre as well as their role in transcriptional repression, it is essential to know their location on the nucleosome. In this study, we have modelled the location of the globular domain of chicken linker histone HS (GHS) on the nuc1eosome. The primary DNA binding site of GH5 was modelled by homology to the co-crystal structure of the E. coli CAP-DNA complex. | en_ZA |
| dc.identifier.apacitation | Koorsen, G. (2001). <i>The association of the secondary DNA-binding site of linker histone H5 in a nucleosome</i>. (Thesis). University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology. Retrieved from http://hdl.handle.net/11427/4282 | en_ZA |
| dc.identifier.chicagocitation | Koorsen, Gerrit. <i>"The association of the secondary DNA-binding site of linker histone H5 in a nucleosome."</i> Thesis., University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology, 2001. http://hdl.handle.net/11427/4282 | en_ZA |
| dc.identifier.citation | Koorsen, G. 2001. The association of the secondary DNA-binding site of linker histone H5 in a nucleosome. University of Cape Town. | en_ZA |
| dc.identifier.ris | TY - Thesis / Dissertation AU - Koorsen, Gerrit AB - In order to understand the role of linker histones in the formation of the 30-run chromatin fibre as well as their role in transcriptional repression, it is essential to know their location on the nucleosome. In this study, we have modelled the location of the globular domain of chicken linker histone HS (GHS) on the nuc1eosome. The primary DNA binding site of GH5 was modelled by homology to the co-crystal structure of the E. coli CAP-DNA complex. DA - 2001 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2001 T1 - The association of the secondary DNA-binding site of linker histone H5 in a nucleosome TI - The association of the secondary DNA-binding site of linker histone H5 in a nucleosome UR - http://hdl.handle.net/11427/4282 ER - | en_ZA |
| dc.identifier.uri | http://hdl.handle.net/11427/4282 | |
| dc.identifier.vancouvercitation | Koorsen G. The association of the secondary DNA-binding site of linker histone H5 in a nucleosome. [Thesis]. University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology, 2001 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/4282 | en_ZA |
| dc.language.iso | eng | en_ZA |
| dc.publisher.department | Department of Molecular and Cell Biology | en_ZA |
| dc.publisher.faculty | Faculty of Science | en_ZA |
| dc.publisher.institution | University of Cape Town | |
| dc.subject.other | Cell Biology | en_ZA |
| dc.title | The association of the secondary DNA-binding site of linker histone H5 in a nucleosome | en_ZA |
| dc.type | Master Thesis | |
| dc.type.qualificationlevel | Masters | |
| dc.type.qualificationname | MSc | en_ZA |
| uct.type.filetype | Text | |
| uct.type.filetype | Image | |
| uct.type.publication | Research | en_ZA |
| uct.type.resource | Thesis | en_ZA |
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