Appropriate indications for positron emission tomography/computed tomography, 2015

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dc.contributor.authorVorster, Mariza
dc.contributor.authorDoruyter, Alexia
dc.contributor.authorBrink, Anita
dc.contributor.authorMkhize, Sonto
dc.contributor.authorHolness, Jen
dc.contributor.authorMalan, Nico
dc.contributor.authorNyakale, Nozipho
dc.contributor.authorWarwick, James M
dc.contributor.authorSathekge, Mike
dc.date.accessioned2021-10-08T07:20:31Z
dc.date.available2021-10-08T07:20:31Z
dc.date.issued2015
dc.description.abstractThese recommendations are intended to serve an important and relevant role in advising referring physicians on the appropriate use of 18F-fluorodeoxyglucose (18F-FDG) and non-18F-FDG positron emission tomography/computed tomography (PET/CT), which can be a powerful tool in patient management in oncology, cardiology, neurology and infection/inflammation. PET is a non-invasive molecular imaging tool that provides tomographic images and quantitative parameters of perfusion, cell viability, proliferation and/or metabolic activity of tissues. These images result from the use of different substances of biological interest (sugars, amino acids, metabolic precursors, hormones) labelled with positron-emitting radionuclides (PET radiopharmaceuticals). Fusion of the aforementioned important functional information with the morphological detail provided by CT as PET/CT provides clinicians with a sensitive and accurate one-step whole-body diagnostic and prognostic tool, which directs and changes patient management. Hence PET/CT is currently the most widely used molecular imaging technology for a patient-tailored treatment approach. In these recommendations we outline which oncological and non-oncological indications are appropriate for PET/CT. Once each combination of pathology and clinical indication is defined, a recommendation is given as: 1. Recommended; 2. Recommended in select cases; 3. May be considered; or 4. Not recommended.
dc.identifier.apacitationVorster, M., Doruyter, A., Brink, A., Mkhize, S., Holness, J., Malan, N., ... Sathekge, M. (2015). Appropriate indications for positron emission tomography/computed tomography, 2015. <i>South African Medical Journal</i>, 106(1), 105 - 177. http://hdl.handle.net/11427/34941en_ZA
dc.identifier.chicagocitationVorster, Mariza, Alexia Doruyter, Anita Brink, Sonto Mkhize, Jen Holness, Nico Malan, Nozipho Nyakale, James M Warwick, and Mike Sathekge "Appropriate indications for positron emission tomography/computed tomography, 2015." <i>South African Medical Journal</i> 106, 1. (2015): 105 - 177. http://hdl.handle.net/11427/34941en_ZA
dc.identifier.citationVorster, M., Doruyter, A., Brink, A., Mkhize, S., Holness, J., Malan, N., Nyakale, N. & Warwick, J.M. et al. 2015. Appropriate indications for positron emission tomography/computed tomography, 2015. <i>South African Medical Journal.</i> 106(1):105 - 177. http://hdl.handle.net/11427/34941en_ZA
dc.identifier.issn0038-2469
dc.identifier.ris TY - Journal Article AU - Vorster, Mariza AU - Doruyter, Alexia AU - Brink, Anita AU - Mkhize, Sonto AU - Holness, Jen AU - Malan, Nico AU - Nyakale, Nozipho AU - Warwick, James M AU - Sathekge, Mike AB - These recommendations are intended to serve an important and relevant role in advising referring physicians on the appropriate use of 18F-fluorodeoxyglucose (18F-FDG) and non-18F-FDG positron emission tomography/computed tomography (PET/CT), which can be a powerful tool in patient management in oncology, cardiology, neurology and infection/inflammation. PET is a non-invasive molecular imaging tool that provides tomographic images and quantitative parameters of perfusion, cell viability, proliferation and/or metabolic activity of tissues. These images result from the use of different substances of biological interest (sugars, amino acids, metabolic precursors, hormones) labelled with positron-emitting radionuclides (PET radiopharmaceuticals). Fusion of the aforementioned important functional information with the morphological detail provided by CT as PET/CT provides clinicians with a sensitive and accurate one-step whole-body diagnostic and prognostic tool, which directs and changes patient management. Hence PET/CT is currently the most widely used molecular imaging technology for a patient-tailored treatment approach. In these recommendations we outline which oncological and non-oncological indications are appropriate for PET/CT. Once each combination of pathology and clinical indication is defined, a recommendation is given as: 1. Recommended; 2. Recommended in select cases; 3. May be considered; or 4. Not recommended. DA - 2015 DB - OpenUCT DP - University of Cape Town IS - 1 J1 - South African Medical Journal LK - https://open.uct.ac.za PY - 2015 SM - 0038-2469 T1 - Appropriate indications for positron emission tomography/computed tomography, 2015 TI - Appropriate indications for positron emission tomography/computed tomography, 2015 UR - http://hdl.handle.net/11427/34941 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/34941
dc.identifier.vancouvercitationVorster M, Doruyter A, Brink A, Mkhize S, Holness J, Malan N, et al. Appropriate indications for positron emission tomography/computed tomography, 2015. South African Medical Journal. 2015;106(1):105 - 177. http://hdl.handle.net/11427/34941.en_ZA
dc.language.isoeng
dc.publisher.departmentDivision of Nuclear Medicine
dc.publisher.facultyFaculty of Health Sciences
dc.sourceSouth African Medical Journal
dc.source.journalissue1
dc.source.journalvolume106
dc.source.pagination105 - 177
dc.source.urihttps://dx.doi.org/10.7196/SAMJ.2016.v106i1.10181
dc.subject.otherHumans
dc.subject.otherMultimodal Imaging
dc.subject.otherNeoplasms
dc.subject.otherPositron-Emission Tomography
dc.subject.otherReproducibility of Results
dc.titleAppropriate indications for positron emission tomography/computed tomography, 2015
dc.typeJournal Article
uct.type.publicationResearch
uct.type.resourceJournal Article
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