Chemoradiation in advanced vulval carcinoma

Master Thesis

2008

Permanent link to this Item
http://hdl.handle.net/11427/3054
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thesis_hsf_2008_rogers_l.pdf (1.13 MB)
Authors
Rogers, Linda Joy
Supervisors
Denny, Lynette
Van Wijk, A L
Journal Title
Link to Journal
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Volume Title
Publisher
Publisher

University of Cape Town

Department
Department of Obstetrics and Gynaecology
Faculty
Faculty of Health Sciences
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Abstract
Vulval carcinoma is uncommon, affecting approximately 2 per 100 000 women annually. The treatment of choice is radical vulvectomy and inguinal lymph node dissection. ‘Advanced’ vulval carcinomas involve midline structures (such as clitoris, urethra or anus) and/or adjacent pelvic organs or bone, and adequate excision may require urinary diversion, colostomy or pelvic exenteration. Less morbid and less mutilating therapeutic alternatives have been investigated, particularly chemoradiation, which has shown significant success in the management of anal carcinomas. Primary chemoradiation has been used, instead of primary radical surgery, to treat advanced vulval carcinomas at Groote Schuur Hospital (GSH) since1982. Aims: 1) To assess the survival of women with advanced vulval carcinoma treated with primary chemoradiation. 2) To examine the role of surgery after treatment with primary chemoradiation.
Description

Includes abstract.


Includes bibliographical references (leaves 68-74).

Keywords
Obstetrics and Gynaecology

Reference:

Rogers, L. 2008. Chemoradiation in advanced vulval carcinoma. University of Cape Town.

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Masters