Metabolic syndrome in type 2 diabetes: comparative prevalence according to two sets of diagnostic criteria in sub-Saharan Africans

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dc.contributor.authorKengne, Andreen_ZA
dc.contributor.authorLimen, Sergeen_ZA
dc.contributor.authorSobngwi, Eugeneen_ZA
dc.contributor.authorDjouogo, Catherine FTen_ZA
dc.contributor.authorNouedoui, Christopheen_ZA
dc.date.accessioned2015-11-18T03:54:38Z
dc.date.available2015-11-18T03:54:38Z
dc.date.issued2012en_ZA
dc.description.abstractBACKGROUND: Available definition criteria for metabolic syndrome (MS) have similarities and inconsistencies. The aim of this study was to determine the prevalence of MS in a group of Cameroonians with type 2 diabetes, according to the International Diabetes Federation (IDF) and the National Cholesterol Education Programme Adult Treatment Panel III (NCEP-ATP III) criteria, and to assess the concordance between both criteria, and the implications of combining them. METHODS: We collected clinical and biochemical data for 308 patients with type 2 diabetes (men 157) at the National Obesity Center of the Yaounde Central Hospital, Cameroon. Concordance was assessed with the use of the Kappa statistic. RESULTS: Mean age (standard deviation) was 55.8 (10.5) years and the median duration of diagnosed diabetes (25th-75th percentiles) was 3years (0.5-5.0), similarly among men and women. The prevalence of MS was 71.7% according to the IDF criteria and 60.4% according to NCEP-ATP III criteria. The prevalence was significantly higher in women than in men independently of the criteria used (both p<0.001). Overall concordance between both definitions was low to average 0.51 (95% confidence interval: 0.41-0.61). Combining the two sets of criteria marginally improved the yield beyond that provided by the IDF criteria alone in men, but not in the overall population and in women. CONCLUSIONS: The IDF and NCEP-ATP III criteria do not always diagnose the same group of diabetic individuals with MS and combining them merely increases the yield beyond that provided by the IDF definition alone. This study highlights the importance of having a single unifying definition for MS in our setting.en_ZA
dc.identifier.apacitationKengne, A., Limen, S., Sobngwi, E., Djouogo, C. F., & Nouedoui, C. (2012). Metabolic syndrome in type 2 diabetes: comparative prevalence according to two sets of diagnostic criteria in sub-Saharan Africans. <i>Diabetology & Metabolic Syndrome</i>, http://hdl.handle.net/11427/15061en_ZA
dc.identifier.chicagocitationKengne, Andre, Serge Limen, Eugene Sobngwi, Catherine FT Djouogo, and Christophe Nouedoui "Metabolic syndrome in type 2 diabetes: comparative prevalence according to two sets of diagnostic criteria in sub-Saharan Africans." <i>Diabetology & Metabolic Syndrome</i> (2012) http://hdl.handle.net/11427/15061en_ZA
dc.identifier.citationKengne, A. P., Limen, S. N., Sobngwi, E., Djouogo, C. F., & Nouedoui, C. (2012). Metabolic syndrome in type 2 diabetes: comparative prevalence according to two sets of diagnostic criteria in sub-Saharan Africans. Diabetol Metab Syndr, 4(1), 22-22.en_ZA
dc.identifier.ris TY - Journal Article AU - Kengne, Andre AU - Limen, Serge AU - Sobngwi, Eugene AU - Djouogo, Catherine FT AU - Nouedoui, Christophe AB - BACKGROUND: Available definition criteria for metabolic syndrome (MS) have similarities and inconsistencies. The aim of this study was to determine the prevalence of MS in a group of Cameroonians with type 2 diabetes, according to the International Diabetes Federation (IDF) and the National Cholesterol Education Programme Adult Treatment Panel III (NCEP-ATP III) criteria, and to assess the concordance between both criteria, and the implications of combining them. METHODS: We collected clinical and biochemical data for 308 patients with type 2 diabetes (men 157) at the National Obesity Center of the Yaounde Central Hospital, Cameroon. Concordance was assessed with the use of the Kappa statistic. RESULTS: Mean age (standard deviation) was 55.8 (10.5) years and the median duration of diagnosed diabetes (25th-75th percentiles) was 3years (0.5-5.0), similarly among men and women. The prevalence of MS was 71.7% according to the IDF criteria and 60.4% according to NCEP-ATP III criteria. The prevalence was significantly higher in women than in men independently of the criteria used (both p<0.001). Overall concordance between both definitions was low to average 0.51 (95% confidence interval: 0.41-0.61). Combining the two sets of criteria marginally improved the yield beyond that provided by the IDF criteria alone in men, but not in the overall population and in women. CONCLUSIONS: The IDF and NCEP-ATP III criteria do not always diagnose the same group of diabetic individuals with MS and combining them merely increases the yield beyond that provided by the IDF definition alone. This study highlights the importance of having a single unifying definition for MS in our setting. DA - 2012 DB - OpenUCT DO - 10.1186/1758-5996-4-22 DP - University of Cape Town J1 - Diabetology & Metabolic Syndrome LK - https://open.uct.ac.za PB - University of Cape Town PY - 2012 T1 - Metabolic syndrome in type 2 diabetes: comparative prevalence according to two sets of diagnostic criteria in sub-Saharan Africans TI - Metabolic syndrome in type 2 diabetes: comparative prevalence according to two sets of diagnostic criteria in sub-Saharan Africans UR - http://hdl.handle.net/11427/15061 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/15061
dc.identifier.urihttp://dx.doi.org/10.1186/1758-5996-4-22
dc.identifier.vancouvercitationKengne A, Limen S, Sobngwi E, Djouogo CF, Nouedoui C. Metabolic syndrome in type 2 diabetes: comparative prevalence according to two sets of diagnostic criteria in sub-Saharan Africans. Diabetology & Metabolic Syndrome. 2012; http://hdl.handle.net/11427/15061.en_ZA
dc.language.isoengen_ZA
dc.publisherBioMed Central Ltden_ZA
dc.publisher.departmentDivision of Cardiologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Licenseen_ZA
dc.rights.holder2012 Kengne et al.; licensee BioMed Central Ltd.en_ZA
dc.rights.urihttp://creativecommons.org/licenses/by/2.0en_ZA
dc.sourceDiabetology & Metabolic Syndromeen_ZA
dc.source.urihttp://www.dmsjournal.com/en_ZA
dc.subject.othermetabolic syndrome (MS)en_ZA
dc.subject.othermetabolic syndrome prevalenceen_ZA
dc.subject.otherCamerooniansen_ZA
dc.subject.othertype 2 diabetesen_ZA
dc.titleMetabolic syndrome in type 2 diabetes: comparative prevalence according to two sets of diagnostic criteria in sub-Saharan Africansen_ZA
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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