Metabolic Syndrome in People Living with Human Immunodeficiency Virus: An Assessment of the Prevalence and the Agreement between Diagnostic Criteria

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dc.contributor.authorNguyen, Kim Anh
dc.contributor.authorPeer, Nasheeta
dc.contributor.authorMatsha, Tandi E
dc.contributor.authorKengne, André Pascal
dc.date.accessioned2021-10-08T07:04:20Z
dc.date.available2021-10-08T07:04:20Z
dc.date.issued2017
dc.description.abstractObjectives. We determined metabolic syndrome (MetS) prevalence and assessed the agreement between different diagnostic criteria in HIV-infected South Africans. Method. A random sample included 748 HIV-infected adult patients (79% women) across 17 HIV healthcare facilities in the Western Cape Province. MetS was defined using the Joint Interim Statement (JIS 2009), International Diabetes Federation (IDF 2005), and Adult Treatment Panel III (ATPIII 2005) criteria. Results. Median values were 38 years (age), 5 years (diagnosed HIV duration), and 392 cells/mm3 (CD4 count), and 93% of the participants were on antiretroviral therapy (ART). MetS prevalence was 28.2% (95%CI: 25–31.4), 26.5% (23.3–29.6), and 24.1% (21–27.1) by the JIS, IDF, and ATPIII 2005 criteria, respectively. Prevalence was always higher in women than in men (all ), in participants with longer duration of diagnosed HIV (all ), and in ART users not receiving 1st-line regimens (all ). The agreement among the three criteria was very good overall and in most subgroups (all ). Conclusions. The three most popular diagnostic criteria yielded similarly high MetS prevalence in this relatively young population receiving care for HIV infection. Very good levels of agreement between criteria are unaffected by some HIV-specific features highlighting the likely comparable diagnostic utility of those criteria in routine HIV care settings.
dc.identifier.apacitationNguyen, K. A., Peer, N., Matsha, T. E., & Kengne, A. P. (2017). Metabolic Syndrome in People Living with Human Immunodeficiency Virus: An Assessment of the Prevalence and the Agreement between Diagnostic Criteria. <i>International Journal of Endocrinology</i>, 2017(4), 174 - 177. http://hdl.handle.net/11427/34485en_ZA
dc.identifier.chicagocitationNguyen, Kim Anh, Nasheeta Peer, Tandi E Matsha, and André Pascal Kengne "Metabolic Syndrome in People Living with Human Immunodeficiency Virus: An Assessment of the Prevalence and the Agreement between Diagnostic Criteria." <i>International Journal of Endocrinology</i> 2017, 4. (2017): 174 - 177. http://hdl.handle.net/11427/34485en_ZA
dc.identifier.citationNguyen, K.A., Peer, N., Matsha, T.E. & Kengne, A.P. 2017. Metabolic Syndrome in People Living with Human Immunodeficiency Virus: An Assessment of the Prevalence and the Agreement between Diagnostic Criteria. <i>International Journal of Endocrinology.</i> 2017(4):174 - 177. http://hdl.handle.net/11427/34485en_ZA
dc.identifier.issn1687-8337
dc.identifier.issn1687-8345
dc.identifier.ris TY - Journal Article AU - Nguyen, Kim Anh AU - Peer, Nasheeta AU - Matsha, Tandi E AU - Kengne, André Pascal AB - Objectives. We determined metabolic syndrome (MetS) prevalence and assessed the agreement between different diagnostic criteria in HIV-infected South Africans. Method. A random sample included 748 HIV-infected adult patients (79% women) across 17 HIV healthcare facilities in the Western Cape Province. MetS was defined using the Joint Interim Statement (JIS 2009), International Diabetes Federation (IDF 2005), and Adult Treatment Panel III (ATPIII 2005) criteria. Results. Median values were 38 years (age), 5 years (diagnosed HIV duration), and 392 cells/mm3 (CD4 count), and 93% of the participants were on antiretroviral therapy (ART). MetS prevalence was 28.2% (95%CI: 25–31.4), 26.5% (23.3–29.6), and 24.1% (21–27.1) by the JIS, IDF, and ATPIII 2005 criteria, respectively. Prevalence was always higher in women than in men (all ), in participants with longer duration of diagnosed HIV (all ), and in ART users not receiving 1st-line regimens (all ). The agreement among the three criteria was very good overall and in most subgroups (all ). Conclusions. The three most popular diagnostic criteria yielded similarly high MetS prevalence in this relatively young population receiving care for HIV infection. Very good levels of agreement between criteria are unaffected by some HIV-specific features highlighting the likely comparable diagnostic utility of those criteria in routine HIV care settings. DA - 2017 DB - OpenUCT DP - University of Cape Town IS - 4 J1 - International Journal of Endocrinology LK - https://open.uct.ac.za PY - 2017 SM - 1687-8337 SM - 1687-8345 T1 - Metabolic Syndrome in People Living with Human Immunodeficiency Virus: An Assessment of the Prevalence and the Agreement between Diagnostic Criteria TI - Metabolic Syndrome in People Living with Human Immunodeficiency Virus: An Assessment of the Prevalence and the Agreement between Diagnostic Criteria UR - http://hdl.handle.net/11427/34485 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/34485
dc.identifier.vancouvercitationNguyen KA, Peer N, Matsha TE, Kengne AP. Metabolic Syndrome in People Living with Human Immunodeficiency Virus: An Assessment of the Prevalence and the Agreement between Diagnostic Criteria. International Journal of Endocrinology. 2017;2017(4):174 - 177. http://hdl.handle.net/11427/34485.en_ZA
dc.language.isoeng
dc.publisher.departmentDepartment of Medicine
dc.publisher.facultyFaculty of Health Sciences
dc.sourceInternational Journal of Endocrinology
dc.source.journalissue4
dc.source.journalvolume2017
dc.source.pagination174 - 177
dc.source.urihttps://dx.doi.org/10.1155/2017/1613657
dc.subject.otherBurns
dc.subject.otherDisaster Planning
dc.subject.otherHumans
dc.subject.otherMass Casualty Incidents
dc.subject.otherNational Health Programs
dc.subject.otherPractice Guidelines as Topic
dc.subject.otherSocieties, Medical
dc.subject.otherSouth Africa
dc.titleMetabolic Syndrome in People Living with Human Immunodeficiency Virus: An Assessment of the Prevalence and the Agreement between Diagnostic Criteria
dc.typeJournal Article
uct.type.publicationResearch
uct.type.resourceJournal Article
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