Wellbeing among sub-Saharan African patients with advanced HIV and/or cancer: an international multicentred comparison study of two outcome measures

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dc.contributor.authorHarding, Richarden_ZA
dc.contributor.authorSelman, Lucyen_ZA
dc.contributor.authorAli, Zippyen_ZA
dc.contributor.authorPowell, Richarden_ZA
dc.contributor.authorNamisango, Eveen_ZA
dc.contributor.authorMwangi-Powell, Faithen_ZA
dc.contributor.authorGwyther, Lizen_ZA
dc.contributor.authorGikaara, Nancyen_ZA
dc.contributor.authorHigginson, Ireneen_ZA
dc.contributor.authorSiegert, Richarden_ZA
dc.date.accessioned2015-11-27T09:34:54Z
dc.date.available2015-11-27T09:34:54Z
dc.date.issued2014en_ZA
dc.description.abstractBACKGROUND: Despite the high mortality rates of HIV and cancer in sub-Saharan Africa, there are few outcome tools and no comparative data across conditions. This study aimed to measure multidimensional wellbeing among advanced HIV and/or cancer patients in three African countries, and determine the relationship between two validated outcome measures. METHODS: Cross-sectional self-reported data from palliative care populations in Kenya, Uganda and South Africa using FACIT-G+Pal and POS measures. RESULTS: Among 461 participants across all countries, subscale "social and family wellbeing" had highest (best) score. Significant country effect showed lower (worse) scores for Uganda on 3 FACIT G subscales: Physical, Social + family, and functional. In multiple regression, country and functional status accounted for 21% variance in FACIT-Pal. Worsening functional status was associated with poorer POS score. Kenyans had worse POS score, followed by Uganda and South Africa. Matrix of correlational coefficients revealed moderate correlation between the POS and FACIT-Pal core scale (0.60), the FACIT-G and POS (0.64), and FACIT-G+Pal with POS (0.66). CONCLUSIONS: The data reveal best status for family and social wellbeing, which may reflect the sample being from less individualistic societies. The tools appear to measure different constructs of wellbeing in palliative care, and reveal different levels of wellbeing between countries. Those with poorest physical function require greatest palliative and supportive care, and this does not appear to differ according to diagnosis.en_ZA
dc.identifier.apacitationHarding, R., Selman, L., Ali, Z., Powell, R., Namisango, E., Mwangi-Powell, F., ... Siegert, R. (2014). Wellbeing among sub-Saharan African patients with advanced HIV and/or cancer: an international multicentred comparison study of two outcome measures. <i>Health and Quality of Life Outcomes</i>, http://hdl.handle.net/11427/15410en_ZA
dc.identifier.chicagocitationHarding, Richard, Lucy Selman, Zippy Ali, Richard Powell, Eve Namisango, Faith Mwangi-Powell, Liz Gwyther, Nancy Gikaara, Irene Higginson, and Richard Siegert "Wellbeing among sub-Saharan African patients with advanced HIV and/or cancer: an international multicentred comparison study of two outcome measures." <i>Health and Quality of Life Outcomes</i> (2014) http://hdl.handle.net/11427/15410en_ZA
dc.identifier.citationHarding, R., Selman, L., Ali, Z., Powell, R. A., Namisango, E., Mwangi-Powell, F., ... & Siegert, R. J. (2014). Wellbeing among sub-Saharan African patients with advanced HIV and/or cancer: an international multicentred comparison study of two outcome measures. Health and Quality of Life Outcomes, 12, 80.en_ZA
dc.identifier.ris TY - Journal Article AU - Harding, Richard AU - Selman, Lucy AU - Ali, Zippy AU - Powell, Richard AU - Namisango, Eve AU - Mwangi-Powell, Faith AU - Gwyther, Liz AU - Gikaara, Nancy AU - Higginson, Irene AU - Siegert, Richard AB - BACKGROUND: Despite the high mortality rates of HIV and cancer in sub-Saharan Africa, there are few outcome tools and no comparative data across conditions. This study aimed to measure multidimensional wellbeing among advanced HIV and/or cancer patients in three African countries, and determine the relationship between two validated outcome measures. METHODS: Cross-sectional self-reported data from palliative care populations in Kenya, Uganda and South Africa using FACIT-G+Pal and POS measures. RESULTS: Among 461 participants across all countries, subscale "social and family wellbeing" had highest (best) score. Significant country effect showed lower (worse) scores for Uganda on 3 FACIT G subscales: Physical, Social + family, and functional. In multiple regression, country and functional status accounted for 21% variance in FACIT-Pal. Worsening functional status was associated with poorer POS score. Kenyans had worse POS score, followed by Uganda and South Africa. Matrix of correlational coefficients revealed moderate correlation between the POS and FACIT-Pal core scale (0.60), the FACIT-G and POS (0.64), and FACIT-G+Pal with POS (0.66). CONCLUSIONS: The data reveal best status for family and social wellbeing, which may reflect the sample being from less individualistic societies. The tools appear to measure different constructs of wellbeing in palliative care, and reveal different levels of wellbeing between countries. Those with poorest physical function require greatest palliative and supportive care, and this does not appear to differ according to diagnosis. DA - 2014 DB - OpenUCT DO - 10.1186/1477-7525-12-80 DP - University of Cape Town J1 - Health and Quality of Life Outcomes LK - https://open.uct.ac.za PB - University of Cape Town PY - 2014 T1 - Wellbeing among sub-Saharan African patients with advanced HIV and/or cancer: an international multicentred comparison study of two outcome measures TI - Wellbeing among sub-Saharan African patients with advanced HIV and/or cancer: an international multicentred comparison study of two outcome measures UR - http://hdl.handle.net/11427/15410 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/15410
dc.identifier.urihttp://dx.doi.org/10.1186/1477-7525-12-80
dc.identifier.vancouvercitationHarding R, Selman L, Ali Z, Powell R, Namisango E, Mwangi-Powell F, et al. Wellbeing among sub-Saharan African patients with advanced HIV and/or cancer: an international multicentred comparison study of two outcome measures. Health and Quality of Life Outcomes. 2014; http://hdl.handle.net/11427/15410.en_ZA
dc.language.isoengen_ZA
dc.publisherBioMed Central Ltden_ZA
dc.publisher.departmentDepartment of Public Health and Family Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Licenseen_ZA
dc.rights.holder2014 Harding et al.; licensee BioMed Central Ltd.en_ZA
dc.rights.urihttp://creativecommons.org/licenses/by/2.0en_ZA
dc.sourceHealth and Quality of Life Outcomesen_ZA
dc.source.urihttp://hqlo.biomedcentral.com/en_ZA
dc.subject.otherSub-Saharan Africaen_ZA
dc.subject.otherHIVen_ZA
dc.subject.otherCanceren_ZA
dc.subject.otherPalliative careen_ZA
dc.subject.otherOutcomeen_ZA
dc.subject.otherSelf-reporten_ZA
dc.titleWellbeing among sub-Saharan African patients with advanced HIV and/or cancer: an international multicentred comparison study of two outcome measuresen_ZA
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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