Anemia in type 2 diabetic patients and correlation with kidney function in a tertiary care sub-Saharan African hospital: a cross-sectional study

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dc.contributor.authorFeteh, Vitalis F
dc.contributor.authorChoukem, Simeon-Pierre
dc.contributor.authorKengne, André Pascal
dc.contributor.authorNebongo, Daniel N
dc.contributor.authorNgowe-Ngowe, Marcelin
dc.date.accessioned2021-10-08T06:54:44Z
dc.date.available2021-10-08T06:54:44Z
dc.date.issued2016
dc.description.abstractBackgroundAnemia is common in diabetic patients and increases morbidity and mortality, but its burden has been less well characterized in sub-Saharan Africans. We determined the prevalence of anemia and investigated the related factors, with a particular focus on the role of declining renal function, in type 2 diabetic patients attending a tertiary health care institution in Cameroon.MethodsHemoglobin (Hb) levels were measured in a consecutive sample of patients with type 2 diabetes, who reported for annual review at the outpatient section of the Douala General Hospital in 2013. Patients were classified as anemic according to the World Health Organisation criteria (Hb < 12g/dl for females and Hb < 13g/dl for males). Estimated glomerular filtration rate (eGFR) was calculated using the abbreviated Modification of Diet in Renal Disease Study Group formula. Determinants of Hb concentration and anemia were investigated using multivariable logistic regressions.ResultsA total of 636 patients were examined including 263 (prevalence rate 41.4%) who had anemia. The prevalence of anemia increased significantly with deteriorating kidney function, although up to 31.9% of patients with normal kidney function had anemia. Compared with their non-anemic counterparts, anemic diabetic patients were older, had longer duration of diabetes, lower eGFR, higher prevalence of proteinuria and diabetic retinopathy (all p < 0.05). In multivariable logistic regressions, eGFR (p = 0.001) and presence of retinopathy (p = 0.023) were the independent determinants of prevalent anemia.ConclusionsThe prevalence of anemia is high in type 2 diabetic patients attending referral institutions in Cameroon, including among those without chronic kidney disease. Routine screening for anemia in all diabetic patients may aid early identification and correction as appropriate.
dc.identifier.apacitationFeteh, V. F., Choukem, S., Kengne, A. P., Nebongo, D. N., & Ngowe-Ngowe, M. (2016). Anemia in type 2 diabetic patients and correlation with kidney function in a tertiary care sub-Saharan African hospital: a cross-sectional study. <i>BMC Nephrology</i>, 17(1), 174 - 177. http://hdl.handle.net/11427/34325en_ZA
dc.identifier.chicagocitationFeteh, Vitalis F, Simeon-Pierre Choukem, André Pascal Kengne, Daniel N Nebongo, and Marcelin Ngowe-Ngowe "Anemia in type 2 diabetic patients and correlation with kidney function in a tertiary care sub-Saharan African hospital: a cross-sectional study." <i>BMC Nephrology</i> 17, 1. (2016): 174 - 177. http://hdl.handle.net/11427/34325en_ZA
dc.identifier.citationFeteh, V.F., Choukem, S., Kengne, A.P., Nebongo, D.N. & Ngowe-Ngowe, M. 2016. Anemia in type 2 diabetic patients and correlation with kidney function in a tertiary care sub-Saharan African hospital: a cross-sectional study. <i>BMC Nephrology.</i> 17(1):174 - 177. http://hdl.handle.net/11427/34325en_ZA
dc.identifier.issn1471-2369
dc.identifier.ris TY - Journal Article AU - Feteh, Vitalis F AU - Choukem, Simeon-Pierre AU - Kengne, André Pascal AU - Nebongo, Daniel N AU - Ngowe-Ngowe, Marcelin AB - BackgroundAnemia is common in diabetic patients and increases morbidity and mortality, but its burden has been less well characterized in sub-Saharan Africans. We determined the prevalence of anemia and investigated the related factors, with a particular focus on the role of declining renal function, in type 2 diabetic patients attending a tertiary health care institution in Cameroon.MethodsHemoglobin (Hb) levels were measured in a consecutive sample of patients with type 2 diabetes, who reported for annual review at the outpatient section of the Douala General Hospital in 2013. Patients were classified as anemic according to the World Health Organisation criteria (Hb < 12g/dl for females and Hb < 13g/dl for males). Estimated glomerular filtration rate (eGFR) was calculated using the abbreviated Modification of Diet in Renal Disease Study Group formula. Determinants of Hb concentration and anemia were investigated using multivariable logistic regressions.ResultsA total of 636 patients were examined including 263 (prevalence rate 41.4%) who had anemia. The prevalence of anemia increased significantly with deteriorating kidney function, although up to 31.9% of patients with normal kidney function had anemia. Compared with their non-anemic counterparts, anemic diabetic patients were older, had longer duration of diabetes, lower eGFR, higher prevalence of proteinuria and diabetic retinopathy (all p < 0.05). In multivariable logistic regressions, eGFR (p = 0.001) and presence of retinopathy (p = 0.023) were the independent determinants of prevalent anemia.ConclusionsThe prevalence of anemia is high in type 2 diabetic patients attending referral institutions in Cameroon, including among those without chronic kidney disease. Routine screening for anemia in all diabetic patients may aid early identification and correction as appropriate. DA - 2016 DB - OpenUCT DP - University of Cape Town IS - 1 J1 - BMC Nephrology LK - https://open.uct.ac.za PY - 2016 SM - 1471-2369 T1 - Anemia in type 2 diabetic patients and correlation with kidney function in a tertiary care sub-Saharan African hospital: a cross-sectional study TI - Anemia in type 2 diabetic patients and correlation with kidney function in a tertiary care sub-Saharan African hospital: a cross-sectional study UR - http://hdl.handle.net/11427/34325 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/34325
dc.identifier.vancouvercitationFeteh VF, Choukem S, Kengne AP, Nebongo DN, Ngowe-Ngowe M. Anemia in type 2 diabetic patients and correlation with kidney function in a tertiary care sub-Saharan African hospital: a cross-sectional study. BMC Nephrology. 2016;17(1):174 - 177. http://hdl.handle.net/11427/34325.en_ZA
dc.language.isoeng
dc.publisher.departmentDepartment of Medicine
dc.publisher.facultyFaculty of Health Sciences
dc.sourceBMC Nephrology
dc.source.journalissue1
dc.source.journalvolume17
dc.source.pagination174 - 177
dc.source.urihttps://dx.doi.org/10.1186/s12882-016-0247-1
dc.subject.otherAnemia
dc.subject.otherCameroon
dc.subject.otherChronic kidney disease
dc.subject.otherDiabetes
dc.subject.otherEstimated glomerular filtration rate
dc.subject.otherHemoglobin
dc.subject.otherAged
dc.subject.otherAnemia
dc.subject.otherCameroon
dc.subject.otherCross-Sectional Studies
dc.subject.otherDiabetes Mellitus, Type 2
dc.subject.otherDiabetic Nephropathies
dc.subject.otherDiabetic Retinopathy
dc.subject.otherFemale
dc.subject.otherGlomerular Filtration Rate
dc.subject.otherHemoglobins
dc.subject.otherHumans
dc.subject.otherLogistic Models
dc.subject.otherMale
dc.subject.otherMiddle Aged
dc.subject.otherMultivariate Analysis
dc.subject.otherPrevalence
dc.subject.otherProteinuria
dc.subject.otherRenal Insufficiency, Chronic
dc.subject.otherRisk Factors
dc.titleAnemia in type 2 diabetic patients and correlation with kidney function in a tertiary care sub-Saharan African hospital: a cross-sectional study
dc.typeJournal Article
uct.type.publicationResearch
uct.type.resourceJournal Article
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