The diagnostic accuracy to Technetium 99m labelled erythrocyte scintigraphy in the investigation of hepatic mass lesions : special reference to hepatic cavernous haemangioma and hepatocellular carcinoma

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dc.contributor.advisorMann, Michael Den_ZA
dc.contributor.authorLourens, Stevenen_ZA
dc.date.accessioned2018-01-29T06:48:06Z
dc.date.available2018-01-29T06:48:06Z
dc.date.issued1995en_ZA
dc.description.abstractThe distinction between cavernous haemangiomas of the liver (which are the second most common hepatic mass lesions) from malignant lesions, is often difficult. An incorrect diagnosis of cavernous haemangioma, in a patient with malignancy, may adversely influence the outcome of subsequent treatment in these patients, due to delay in therapy. Although previous studies have suggested that ⁹⁹ᵐTc erythrocyte blood pool scintigraphy is both highly sensitive and specific for haemangiomas, a basic flaw in all previous studies has been the small number of control patients studied. Bayesian analysis clearly shows that specificity for a test is dependant on the pre-test probability of the lesion being present. Thus all the studies done to date, may reflect an inappropriately high specificity for ⁹⁹ᵐTc scintigraphy, in diagnosing cavernous haemangiomas, because they have mainly studied patients with haemangiomas and relatively few patients with other lesions. This study was thus undertaken to clarify the true accuracy of this technique, in distinguishing haemangiomas from other hepatic mass lesions, by studying a large number of patients with haemangiomas and other hepatic mass lesions.en_ZA
dc.identifier.apacitationLourens, S. (1995). <i>The diagnostic accuracy to Technetium 99m labelled erythrocyte scintigraphy in the investigation of hepatic mass lesions : special reference to hepatic cavernous haemangioma and hepatocellular carcinoma</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Nuclear Medicine. Retrieved from http://hdl.handle.net/11427/27037en_ZA
dc.identifier.chicagocitationLourens, Steven. <i>"The diagnostic accuracy to Technetium 99m labelled erythrocyte scintigraphy in the investigation of hepatic mass lesions : special reference to hepatic cavernous haemangioma and hepatocellular carcinoma."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Nuclear Medicine, 1995. http://hdl.handle.net/11427/27037en_ZA
dc.identifier.citationLourens, S. 1995. The diagnostic accuracy to Technetium 99m labelled erythrocyte scintigraphy in the investigation of hepatic mass lesions : special reference to hepatic cavernous haemangioma and hepatocellular carcinoma. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Lourens, Steven AB - The distinction between cavernous haemangiomas of the liver (which are the second most common hepatic mass lesions) from malignant lesions, is often difficult. An incorrect diagnosis of cavernous haemangioma, in a patient with malignancy, may adversely influence the outcome of subsequent treatment in these patients, due to delay in therapy. Although previous studies have suggested that ⁹⁹ᵐTc erythrocyte blood pool scintigraphy is both highly sensitive and specific for haemangiomas, a basic flaw in all previous studies has been the small number of control patients studied. Bayesian analysis clearly shows that specificity for a test is dependant on the pre-test probability of the lesion being present. Thus all the studies done to date, may reflect an inappropriately high specificity for ⁹⁹ᵐTc scintigraphy, in diagnosing cavernous haemangiomas, because they have mainly studied patients with haemangiomas and relatively few patients with other lesions. This study was thus undertaken to clarify the true accuracy of this technique, in distinguishing haemangiomas from other hepatic mass lesions, by studying a large number of patients with haemangiomas and other hepatic mass lesions. DA - 1995 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 1995 T1 - The diagnostic accuracy to Technetium 99m labelled erythrocyte scintigraphy in the investigation of hepatic mass lesions : special reference to hepatic cavernous haemangioma and hepatocellular carcinoma TI - The diagnostic accuracy to Technetium 99m labelled erythrocyte scintigraphy in the investigation of hepatic mass lesions : special reference to hepatic cavernous haemangioma and hepatocellular carcinoma UR - http://hdl.handle.net/11427/27037 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/27037
dc.identifier.vancouvercitationLourens S. The diagnostic accuracy to Technetium 99m labelled erythrocyte scintigraphy in the investigation of hepatic mass lesions : special reference to hepatic cavernous haemangioma and hepatocellular carcinoma. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Nuclear Medicine, 1995 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/27037en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDivision of Nuclear Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherNuclear Medicineen_ZA
dc.subject.otherCarcinoma, Hepatocellular - radionuclide imagingen_ZA
dc.subject.otherHemangioma, Cavernous - radionuclide imagingen_ZA
dc.subject.otherRadionuclide imaging - Methodsen_ZA
dc.subject.otherTechnetium - diagnostic useen_ZA
dc.titleThe diagnostic accuracy to Technetium 99m labelled erythrocyte scintigraphy in the investigation of hepatic mass lesions : special reference to hepatic cavernous haemangioma and hepatocellular carcinomaen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMMeden_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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