Antenatal depressive symptoms and perinatal complications: a prospective study in rural Ethiopia
| dc.contributor.author | Bitew, Tesera | |
| dc.contributor.author | Hanlon, Charlotte | |
| dc.contributor.author | Kebede, Eskinder | |
| dc.contributor.author | Honikman, Simone | |
| dc.contributor.author | Fekadu, Abebaw | |
| dc.date.accessioned | 2017-09-05T09:11:28Z | |
| dc.date.available | 2017-09-05T09:11:28Z | |
| dc.date.issued | 2017-08-22 | |
| dc.date.updated | 2017-08-27T03:16:11Z | |
| dc.description.abstract | Background: Antenatal depressive symptoms affect around 12.3% of women in in low and middle income countries (LMICs) and data are accumulating about associations with adverse outcomes for mother and child. Studies from rural, low-income country community samples are limited. This paper aims to investigate whether antenatal depressive symptoms predict perinatal complications in a rural Ethiopia setting. Methods: A population-based prospective study was conducted in Sodo district, southern Ethiopia. A total of 1240 women recruited in the second and third trimesters of pregnancy were followed up until 4 to 12 weeks postpartum. Antenatal depressive symptoms were assessed using a locally validated version of the Patient Health Questionnaire (PHQ-9) that at a cut-off score of five or more indicates probable depression. Self-report of perinatal complications, categorised as maternal and neonatal were collected by using structured interviewer administered questionnaires at a median of eight weeks post-partum. Multivariate analysis was conducted to examine the association between antenatal depressive symptoms and self-reported perinatal complications. Result: A total of 28.7% of women had antenatal depressive symptoms (PHQ-9 score ≥ 5). Women with antenatal depressive symptoms had more than twice the odds of self-reported complications in pregnancy (OR=2.44, 95% CI: 1.84, 3.23), labour (OR= 1.84 95% CI: 1.34, 2.53) and the postpartum period (OR=1.70, 95% CI: 1.23, 2.35) compared to women without these symptoms. There was no association between antenatal depressive symptoms and pregnancy loss or neonatal death. Conclusion: Antenatal depressive symptoms are associated prospectively with self-reports of perinatal complications. Further research is necessary to further confirm these findings in a rural and poor context using objective measures of complications and investigating whether early detection and treatment of depressive symptoms reduces these complications. | |
| dc.identifier.apacitation | Bitew, T., Hanlon, C., Kebede, E., Honikman, S., & Fekadu, A. (2017). Antenatal depressive symptoms and perinatal complications: a prospective study in rural Ethiopia. <i>BMC Psychiatry</i>, http://hdl.handle.net/11427/25036 | en_ZA |
| dc.identifier.chicagocitation | Bitew, Tesera, Charlotte Hanlon, Eskinder Kebede, Simone Honikman, and Abebaw Fekadu "Antenatal depressive symptoms and perinatal complications: a prospective study in rural Ethiopia." <i>BMC Psychiatry</i> (2017) http://hdl.handle.net/11427/25036 | en_ZA |
| dc.identifier.citation | Bitew, T., Hanlon, C., Kebede, E., Honikman, S., & Fekadu, A. (2017). Antenatal depressive symptoms and perinatal complications: a prospective study in rural Ethiopia. BMC psychiatry, 17(1), 301. | |
| dc.identifier.ris | TY - Journal Article AU - Bitew, Tesera AU - Hanlon, Charlotte AU - Kebede, Eskinder AU - Honikman, Simone AU - Fekadu, Abebaw AB - Background: Antenatal depressive symptoms affect around 12.3% of women in in low and middle income countries (LMICs) and data are accumulating about associations with adverse outcomes for mother and child. Studies from rural, low-income country community samples are limited. This paper aims to investigate whether antenatal depressive symptoms predict perinatal complications in a rural Ethiopia setting. Methods: A population-based prospective study was conducted in Sodo district, southern Ethiopia. A total of 1240 women recruited in the second and third trimesters of pregnancy were followed up until 4 to 12 weeks postpartum. Antenatal depressive symptoms were assessed using a locally validated version of the Patient Health Questionnaire (PHQ-9) that at a cut-off score of five or more indicates probable depression. Self-report of perinatal complications, categorised as maternal and neonatal were collected by using structured interviewer administered questionnaires at a median of eight weeks post-partum. Multivariate analysis was conducted to examine the association between antenatal depressive symptoms and self-reported perinatal complications. Result: A total of 28.7% of women had antenatal depressive symptoms (PHQ-9 score ≥ 5). Women with antenatal depressive symptoms had more than twice the odds of self-reported complications in pregnancy (OR=2.44, 95% CI: 1.84, 3.23), labour (OR= 1.84 95% CI: 1.34, 2.53) and the postpartum period (OR=1.70, 95% CI: 1.23, 2.35) compared to women without these symptoms. There was no association between antenatal depressive symptoms and pregnancy loss or neonatal death. Conclusion: Antenatal depressive symptoms are associated prospectively with self-reports of perinatal complications. Further research is necessary to further confirm these findings in a rural and poor context using objective measures of complications and investigating whether early detection and treatment of depressive symptoms reduces these complications. DA - 2017-08-22 DB - OpenUCT DO - 10.1186/s12888-017-1462-4 DP - University of Cape Town J1 - BMC Psychiatry LK - https://open.uct.ac.za PB - University of Cape Town PY - 2017 T1 - Antenatal depressive symptoms and perinatal complications: a prospective study in rural Ethiopia TI - Antenatal depressive symptoms and perinatal complications: a prospective study in rural Ethiopia UR - http://hdl.handle.net/11427/25036 ER - | en_ZA |
| dc.identifier.uri | http://dx.doi.org/10.1186/s12888-017-1462-4 | |
| dc.identifier.uri | http://hdl.handle.net/11427/25036 | |
| dc.identifier.vancouvercitation | Bitew T, Hanlon C, Kebede E, Honikman S, Fekadu A. Antenatal depressive symptoms and perinatal complications: a prospective study in rural Ethiopia. BMC Psychiatry. 2017; http://hdl.handle.net/11427/25036. | en_ZA |
| dc.language.iso | en | |
| dc.publisher | BioMed Central | |
| dc.publisher.department | Department of Psychiatry and Mental Health | en_ZA |
| dc.publisher.faculty | Faculty of Health Sciences | en_ZA |
| dc.publisher.institution | University of Cape Town | |
| dc.rights.holder | The Author(s). | |
| dc.source | BMC Psychiatry | |
| dc.source.uri | https://bmcpsychiatry.biomedcentral.com/ | |
| dc.subject.other | Antenatal depressive symptoms | |
| dc.subject.other | Perinatal complications | |
| dc.subject.other | Prospective study | |
| dc.subject.other | Rural and low income | |
| dc.subject.other | Ethiopia | |
| dc.title | Antenatal depressive symptoms and perinatal complications: a prospective study in rural Ethiopia | |
| dc.type | Journal Article | |
| uct.type.filetype | Text | |
| uct.type.filetype | Image |