Investigating the role of a yeast membrane protein, HSP30 in tolerance to ethanol stress

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dc.contributor.advisorLindsey, George Gen_ZA
dc.contributor.advisorBrandt, Wolf Fen_ZA
dc.contributor.authorTsekoa, Tsepoen_ZA
dc.date.accessioned2014-07-30T17:42:11Z
dc.date.available2014-07-30T17:42:11Z
dc.date.issued2001en_ZA
dc.descriptionBibliography: leaves 59-64.
dc.description.abstractOne of the contributors of the widespread interest the yeast Saccharomyces cerevisiae has received is its ability to yield and tolerate high levels of ethanol. S. cerevisiae is able to grow and remain viable in growth media containing ethanol concentrations as high as 19.8% (w/v), a level that is toxic to many other microorganisms. Since production of ethanol is a normal event in the growth cycyle of S. cerevisiae, this organisms has evolved a number of mechanisms to cope with deleterious effects of ethanol. These include induction of heat shock proteins (HSPs). Among these, HSP30 is particularly interesting in that it is the only stress-induced protein known to be instrinsically bound to the yeast plasma membrane. Another ethanol induced HSP; HSP12 has previously been shown to have a peripheral plasma membrane localisation. It has further been shown that HSP12 protects liposomes against damage by ethanol. This study was initially aimed at investigating whether there is co-operation between HSP30 and HSP12 in this membrane protection role.en_ZA
dc.identifier.apacitationTsekoa, T. (2001). <i>Investigating the role of a yeast membrane protein, HSP30 in tolerance to ethanol stress</i>. (Thesis). University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology. Retrieved from http://hdl.handle.net/11427/4342en_ZA
dc.identifier.chicagocitationTsekoa, Tsepo. <i>"Investigating the role of a yeast membrane protein, HSP30 in tolerance to ethanol stress."</i> Thesis., University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology, 2001. http://hdl.handle.net/11427/4342en_ZA
dc.identifier.citationTsekoa, T. 2001. Investigating the role of a yeast membrane protein, HSP30 in tolerance to ethanol stress. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Tsekoa, Tsepo AB - One of the contributors of the widespread interest the yeast Saccharomyces cerevisiae has received is its ability to yield and tolerate high levels of ethanol. S. cerevisiae is able to grow and remain viable in growth media containing ethanol concentrations as high as 19.8% (w/v), a level that is toxic to many other microorganisms. Since production of ethanol is a normal event in the growth cycyle of S. cerevisiae, this organisms has evolved a number of mechanisms to cope with deleterious effects of ethanol. These include induction of heat shock proteins (HSPs). Among these, HSP30 is particularly interesting in that it is the only stress-induced protein known to be instrinsically bound to the yeast plasma membrane. Another ethanol induced HSP; HSP12 has previously been shown to have a peripheral plasma membrane localisation. It has further been shown that HSP12 protects liposomes against damage by ethanol. This study was initially aimed at investigating whether there is co-operation between HSP30 and HSP12 in this membrane protection role. DA - 2001 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2001 T1 - Investigating the role of a yeast membrane protein, HSP30 in tolerance to ethanol stress TI - Investigating the role of a yeast membrane protein, HSP30 in tolerance to ethanol stress UR - http://hdl.handle.net/11427/4342 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/4342
dc.identifier.vancouvercitationTsekoa T. Investigating the role of a yeast membrane protein, HSP30 in tolerance to ethanol stress. [Thesis]. University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology, 2001 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/4342en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Molecular and Cell Biologyen_ZA
dc.publisher.facultyFaculty of Scienceen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherCell Biologyen_ZA
dc.titleInvestigating the role of a yeast membrane protein, HSP30 in tolerance to ethanol stressen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMScen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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