Investigation of the crystallisation inhibitory properties of albumin isolated from the urine of Black and White South Africans

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dc.contributor.authorMensah, Priscilla DNAen_ZA
dc.date.accessioned2014-09-11T06:49:42Z
dc.date.available2014-09-11T06:49:42Z
dc.date.issued2004en_ZA
dc.descriptionBibliography: leaves 81-94.en_ZA
dc.description.abstractStone incidence in South African blacks is extremely rare. The hypothesis to be tested is whether this apparent immunity can be attributed to the presence of more potent inhibitors of calcium oxalate (CaOx) crystallisation in urine from blacks compared to those occurring in the urine of white subjects. Urinary proteins have been shown to be inhibitors. This study investigated the crystallisation inhibitory properties of albumin isolated from the urine of healthy black (BA) and healthy white (WA) South Africans as well as those of human serum albumin (HSA). Albumin was selected because previous studies on other population groups had revealed that the protein inhibits CaOx aggregation. This observation is significant because crystal aggregation is considered to be more important for stone formation than crystal nucleation or growth.en_ZA
dc.identifier.apacitationMensah, P. D. (2004). <i>Investigation of the crystallisation inhibitory properties of albumin isolated from the urine of Black and White South Africans</i>. (Thesis). University of Cape Town ,Faculty of Science ,Department of Chemistry. Retrieved from http://hdl.handle.net/11427/7423en_ZA
dc.identifier.chicagocitationMensah, Priscilla DNA. <i>"Investigation of the crystallisation inhibitory properties of albumin isolated from the urine of Black and White South Africans."</i> Thesis., University of Cape Town ,Faculty of Science ,Department of Chemistry, 2004. http://hdl.handle.net/11427/7423en_ZA
dc.identifier.citationMensah, P. 2004. Investigation of the crystallisation inhibitory properties of albumin isolated from the urine of Black and White South Africans. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Mensah, Priscilla DNA AB - Stone incidence in South African blacks is extremely rare. The hypothesis to be tested is whether this apparent immunity can be attributed to the presence of more potent inhibitors of calcium oxalate (CaOx) crystallisation in urine from blacks compared to those occurring in the urine of white subjects. Urinary proteins have been shown to be inhibitors. This study investigated the crystallisation inhibitory properties of albumin isolated from the urine of healthy black (BA) and healthy white (WA) South Africans as well as those of human serum albumin (HSA). Albumin was selected because previous studies on other population groups had revealed that the protein inhibits CaOx aggregation. This observation is significant because crystal aggregation is considered to be more important for stone formation than crystal nucleation or growth. DA - 2004 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2004 T1 - Investigation of the crystallisation inhibitory properties of albumin isolated from the urine of Black and White South Africans TI - Investigation of the crystallisation inhibitory properties of albumin isolated from the urine of Black and White South Africans UR - http://hdl.handle.net/11427/7423 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/7423
dc.identifier.vancouvercitationMensah PD. Investigation of the crystallisation inhibitory properties of albumin isolated from the urine of Black and White South Africans. [Thesis]. University of Cape Town ,Faculty of Science ,Department of Chemistry, 2004 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/7423en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Chemistryen_ZA
dc.publisher.facultyFaculty of Scienceen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherChemistryen_ZA
dc.titleInvestigation of the crystallisation inhibitory properties of albumin isolated from the urine of Black and White South Africansen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMScen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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