Single frequency whole-body impedance studies in children with diarrhoeal disease and development of a variable frequency system

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dc.contributor.advisorBunn, Anthony E
dc.contributor.authorMoshal, David Clive
dc.contributor.authorMoshal, David Clive
dc.date.accessioned2017-08-23T13:08:42Z
dc.date.available2017-08-23T13:08:42Z
dc.date.issued1993
dc.date.updated2017-07-12T08:20:42Z
dc.description.abstractDiarrhoeal disease is a major cause of infant mortality in this and other developing countries. The assessment of the degree of dehydration in these children is often based on subjective findings alone. These have been shown to be inaccurate as an assessment of the degree of dehydration. Whole-body impedance (WBI) is a method of measuring total body water which is used to assess body composition. This WBI technology, which operates at a single frequency, has been applied to the assessment of dehydration in children with diarrhoeal disease. The normal range of WBI was determined on a group of normally hydrated children and was found to have a mean of 746 Ω, a standard deviation of 85 Ω and 95 % confidence interval for the mean from 720 Ω to 772 Ω. WBI did not depend on age, mass, height or sex. The WBI of a group of children dehydrated from infantile gastroenteritis was measured both before and after rehydration. The dehydrated group had a mean WBI on admission of 1089 Ω and a standard deviation of 149 Ω with a 95 % confidence interval for the mean from 950 Ω to 1109 Ω. This value was significantly greater than that of the normal group. The WBI of the dehydrated group after rehydration was not significantly different from the normal group. In addition a variable frequency bioimpedance analyser was designed and tested. It was found to have an error of less than 1 % over the frequency range 1 to 100 kHz. The device was evaluated on 11 normal and dehydrated children. Four dehydrated children were tested before and after rehydration and this data was compared to a standard electrical model for WBI. It was found that the model could represent the measured data over this frequency range. The extracellular resistive element of the model was mainly responsible for the changes seen during rehydration, suggesting that dehydration in gastroenteritis is mainly due to fluid loss from the ECF compartment.
dc.identifier.apacitationMoshal, D. C., & Moshal, D. C. (1993). <i>Single frequency whole-body impedance studies in children with diarrhoeal disease and development of a variable frequency system</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Biomedical Engineering. Retrieved from http://hdl.handle.net/11427/24955en_ZA
dc.identifier.chicagocitationMoshal, David Clive, and David Clive Moshal. <i>"Single frequency whole-body impedance studies in children with diarrhoeal disease and development of a variable frequency system."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Biomedical Engineering, 1993. http://hdl.handle.net/11427/24955en_ZA
dc.identifier.citationMoshal, D., Moshal, D. 1993. Single frequency whole-body impedance studies in children with diarrhoeal disease and development of a variable frequency system. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Moshal, David Clive AU - Moshal, David Clive AB - Diarrhoeal disease is a major cause of infant mortality in this and other developing countries. The assessment of the degree of dehydration in these children is often based on subjective findings alone. These have been shown to be inaccurate as an assessment of the degree of dehydration. Whole-body impedance (WBI) is a method of measuring total body water which is used to assess body composition. This WBI technology, which operates at a single frequency, has been applied to the assessment of dehydration in children with diarrhoeal disease. The normal range of WBI was determined on a group of normally hydrated children and was found to have a mean of 746 Ω, a standard deviation of 85 Ω and 95 % confidence interval for the mean from 720 Ω to 772 Ω. WBI did not depend on age, mass, height or sex. The WBI of a group of children dehydrated from infantile gastroenteritis was measured both before and after rehydration. The dehydrated group had a mean WBI on admission of 1089 Ω and a standard deviation of 149 Ω with a 95 % confidence interval for the mean from 950 Ω to 1109 Ω. This value was significantly greater than that of the normal group. The WBI of the dehydrated group after rehydration was not significantly different from the normal group. In addition a variable frequency bioimpedance analyser was designed and tested. It was found to have an error of less than 1 % over the frequency range 1 to 100 kHz. The device was evaluated on 11 normal and dehydrated children. Four dehydrated children were tested before and after rehydration and this data was compared to a standard electrical model for WBI. It was found that the model could represent the measured data over this frequency range. The extracellular resistive element of the model was mainly responsible for the changes seen during rehydration, suggesting that dehydration in gastroenteritis is mainly due to fluid loss from the ECF compartment. DA - 1993 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 1993 T1 - Single frequency whole-body impedance studies in children with diarrhoeal disease and development of a variable frequency system TI - Single frequency whole-body impedance studies in children with diarrhoeal disease and development of a variable frequency system UR - http://hdl.handle.net/11427/24955 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/24955
dc.identifier.vancouvercitationMoshal DC, Moshal DC. Single frequency whole-body impedance studies in children with diarrhoeal disease and development of a variable frequency system. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Biomedical Engineering, 1993 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/24955en_ZA
dc.language.isoeng
dc.language.isoeng
dc.publisher.departmentDivision of Biomedical Engineeringen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherDiarrhea, Infantile
dc.subject.otherDehydration - In infancy and childhood
dc.subject.otherElectric Impedance
dc.subject.otherWhole-Body Counting - methods
dc.subject.otherInfantile Diarrhea
dc.subject.otherBiomedical Engineering
dc.titleSingle frequency whole-body impedance studies in children with diarrhoeal disease and development of a variable frequency system
dc.titleSingle frequency whole-body impedance studies in children with diarrhoeal disease and development of a variable frequency system
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMPhil
uct.type.filetype
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearch
uct.type.resourceThesis
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