Beware of 'normal' creatine kinase levels in HIV-associated polmyositis

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dc.contributor.authorHeckmann, Janine
dc.contributor.authorPillay, Komala
dc.contributor.authorKenyon, Christopher R
dc.date.accessioned2018-04-05T14:44:53Z
dc.date.available2018-04-05T14:44:53Z
dc.date.issued2010
dc.date.updated2016-01-21T09:09:58Z
dc.description.abstractGeneralised weakness may be a common complaint of persons infected with HIV, but the development of significant proximal weakness requires specific attention. Polymyositis may occur in HIV infection and is readily treatable with prednisone. Elevated creatine kinase (CK) levels have been regarded as an important criterion for diagnosing polymyositis. A study of HIV-associated polymyositis reported similarly elevated CK levels to those observed in non-HIV settings.1 However, muscle inflammation can be associated with normal or near-normal CK levels. We report 4 cases of HIV-associated polymyositis in which the diagnosis was almost missed owing to the absence of raised CK levels.
dc.identifier.apacitationHeckmann, J., Pillay, K., & Kenyon, C. R. (2010). Beware of 'normal' creatine kinase levels in HIV-associated polmyositis. <i>South African Medical Journal</i>, http://hdl.handle.net/11427/27762en_ZA
dc.identifier.chicagocitationHeckmann, Janine, Komala Pillay, and Christopher R Kenyon "Beware of 'normal' creatine kinase levels in HIV-associated polmyositis." <i>South African Medical Journal</i> (2010) http://hdl.handle.net/11427/27762en_ZA
dc.identifier.citationKenyon, C., Pillay, K., & Heckmann, J. M. (2010). Beware of'normal'creatine kinase levels in HIV-associated polymyositis. SAMJ: South African Medical Journal, 100(3), 156-157.
dc.identifier.ris TY - Journal Article AU - Heckmann, Janine AU - Pillay, Komala AU - Kenyon, Christopher R AB - Generalised weakness may be a common complaint of persons infected with HIV, but the development of significant proximal weakness requires specific attention. Polymyositis may occur in HIV infection and is readily treatable with prednisone. Elevated creatine kinase (CK) levels have been regarded as an important criterion for diagnosing polymyositis. A study of HIV-associated polymyositis reported similarly elevated CK levels to those observed in non-HIV settings.1 However, muscle inflammation can be associated with normal or near-normal CK levels. We report 4 cases of HIV-associated polymyositis in which the diagnosis was almost missed owing to the absence of raised CK levels. DA - 2010 DB - OpenUCT DP - University of Cape Town J1 - South African Medical Journal LK - https://open.uct.ac.za PB - University of Cape Town PY - 2010 T1 - Beware of 'normal' creatine kinase levels in HIV-associated polmyositis TI - Beware of 'normal' creatine kinase levels in HIV-associated polmyositis UR - http://hdl.handle.net/11427/27762 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/27762
dc.identifier.vancouvercitationHeckmann J, Pillay K, Kenyon CR. Beware of 'normal' creatine kinase levels in HIV-associated polmyositis. South African Medical Journal. 2010; http://hdl.handle.net/11427/27762.en_ZA
dc.language.isoeng
dc.publisher.departmentDivision of Infectious Disease and HIV Meden_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.sourceSouth African Medical Journal
dc.source.urihttp://www.samj.org.za/index.php/samj
dc.titleBeware of 'normal' creatine kinase levels in HIV-associated polmyositis
dc.typeJournal Article
uct.type.filetypeText
uct.type.filetypeImage
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