Abstracts reporting of HIV/AIDS randomized controlled trials in general medicine and infectious diseases journals: completeness to date and improvement in the quality since CONSORT extension for abstracts

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dc.contributor.authorBigna, Jean Joel R
dc.contributor.authorNoubiap, Jean Jacques N
dc.contributor.authorAsangbeh, Serra Lem
dc.contributor.authorUm, Lewis N
dc.contributor.authorSimé, Paule Sandra D
dc.contributor.authorTemfack, Elvis
dc.contributor.authorTejiokem, Mathurin Cyrille
dc.date.accessioned2021-10-08T06:54:42Z
dc.date.available2021-10-08T06:54:42Z
dc.date.issued2016
dc.description.abstractAbstract Background Sufficiently detailed abstracts of randomized controlled trials (RCTs) are important, because readers often base their assessment of a trial solely on information in the abstract. We aimed at comparing reporting quality of RCTs in HIV/AIDS medicine before and after the publication of the 2008 CONSORT extension for abstracts and to investigate factors associated with better reporting quality. Methods We searched PubMed/Medline for HIV/AIDS RCTs published between 2006–07 (Pre-CONSORT) and 2014–15 (Post-CONSORT) in 40 leading general medicine and infectious diseases journals. Two investigators extracted data and scored abstracts. The primary outcome was the adjusted mean number of items reported among the 17 required. Proportions of abstracts reporting each of 17 items were considered as secondary outcome. The adjustment was done for journal field, CONSORT endorsement, abstract format, type of intervention, journal impact factor and authorship. This study received no funding. Results The adjusted mean number of reported items was 7.2 (95 % CI 6.6–7.7) in pre-CONSORT (n = 159) and 7.8 (95 % confidence interval [CI] 7.3–8.4) in post-CONSORT (n = 153) (mean difference 0.7; 95 % CI 0.1–1.2). Journal high impact factor (adjusted incidence rate ratio 2.16; 95 % CI 1.83–2.54), abstract with 13 authors or more (1.39; 95 % CI 1.07–1.79) and non-pharmacological intervention (1.19; 95 % CI 1.03–1.37) were independent factors for better reporting quality. There were significant improvements in reporting on participants, randomization, outcome results, registration and funding; regression for author contact; and no change for other items: title, design, interventions, objective, primary outcome, blinding, number randomized, recruitment, number analyzed, harms and conclusions. Conclusions After the publication of the CONSORT extension for abstracts, the reporting quality of HIV/AIDS RCT abstracts in general medicine and infectious diseases journals has suboptimally improved. Thus, stricter adherence to the CONSORT for abstract are needed to improve the reporting quality of HIV/AIDS RCT abstracts.
dc.identifier.apacitationBigna, J. J. R., Noubiap, J. J. N., Asangbeh, S. L., Um, L. N., Simé, P. S. D., Temfack, E., & Tejiokem, M. C. (2016). Abstracts reporting of HIV/AIDS randomized controlled trials in general medicine and infectious diseases journals: completeness to date and improvement in the quality since CONSORT extension for abstracts. <i>BMC Medical Research Methodology</i>, 16(1), 174 - 177. http://hdl.handle.net/11427/34314en_ZA
dc.identifier.chicagocitationBigna, Jean Joel R, Jean Jacques N Noubiap, Serra Lem Asangbeh, Lewis N Um, Paule Sandra D Simé, Elvis Temfack, and Mathurin Cyrille Tejiokem "Abstracts reporting of HIV/AIDS randomized controlled trials in general medicine and infectious diseases journals: completeness to date and improvement in the quality since CONSORT extension for abstracts." <i>BMC Medical Research Methodology</i> 16, 1. (2016): 174 - 177. http://hdl.handle.net/11427/34314en_ZA
dc.identifier.citationBigna, J.J.R., Noubiap, J.J.N., Asangbeh, S.L., Um, L.N., Simé, P.S.D., Temfack, E. & Tejiokem, M.C. 2016. Abstracts reporting of HIV/AIDS randomized controlled trials in general medicine and infectious diseases journals: completeness to date and improvement in the quality since CONSORT extension for abstracts. <i>BMC Medical Research Methodology.</i> 16(1):174 - 177. http://hdl.handle.net/11427/34314en_ZA
dc.identifier.issn1471-2288
dc.identifier.ris TY - Journal Article AU - Bigna, Jean Joel R AU - Noubiap, Jean Jacques N AU - Asangbeh, Serra Lem AU - Um, Lewis N AU - Simé, Paule Sandra D AU - Temfack, Elvis AU - Tejiokem, Mathurin Cyrille AB - Abstract Background Sufficiently detailed abstracts of randomized controlled trials (RCTs) are important, because readers often base their assessment of a trial solely on information in the abstract. We aimed at comparing reporting quality of RCTs in HIV/AIDS medicine before and after the publication of the 2008 CONSORT extension for abstracts and to investigate factors associated with better reporting quality. Methods We searched PubMed/Medline for HIV/AIDS RCTs published between 2006–07 (Pre-CONSORT) and 2014–15 (Post-CONSORT) in 40 leading general medicine and infectious diseases journals. Two investigators extracted data and scored abstracts. The primary outcome was the adjusted mean number of items reported among the 17 required. Proportions of abstracts reporting each of 17 items were considered as secondary outcome. The adjustment was done for journal field, CONSORT endorsement, abstract format, type of intervention, journal impact factor and authorship. This study received no funding. Results The adjusted mean number of reported items was 7.2 (95 % CI 6.6–7.7) in pre-CONSORT (n = 159) and 7.8 (95 % confidence interval [CI] 7.3–8.4) in post-CONSORT (n = 153) (mean difference 0.7; 95 % CI 0.1–1.2). Journal high impact factor (adjusted incidence rate ratio 2.16; 95 % CI 1.83–2.54), abstract with 13 authors or more (1.39; 95 % CI 1.07–1.79) and non-pharmacological intervention (1.19; 95 % CI 1.03–1.37) were independent factors for better reporting quality. There were significant improvements in reporting on participants, randomization, outcome results, registration and funding; regression for author contact; and no change for other items: title, design, interventions, objective, primary outcome, blinding, number randomized, recruitment, number analyzed, harms and conclusions. Conclusions After the publication of the CONSORT extension for abstracts, the reporting quality of HIV/AIDS RCT abstracts in general medicine and infectious diseases journals has suboptimally improved. Thus, stricter adherence to the CONSORT for abstract are needed to improve the reporting quality of HIV/AIDS RCT abstracts. DA - 2016 DB - OpenUCT DP - University of Cape Town IS - 1 J1 - BMC Medical Research Methodology LK - https://open.uct.ac.za PY - 2016 SM - 1471-2288 T1 - Abstracts reporting of HIV/AIDS randomized controlled trials in general medicine and infectious diseases journals: completeness to date and improvement in the quality since CONSORT extension for abstracts TI - Abstracts reporting of HIV/AIDS randomized controlled trials in general medicine and infectious diseases journals: completeness to date and improvement in the quality since CONSORT extension for abstracts UR - http://hdl.handle.net/11427/34314 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/34314
dc.identifier.vancouvercitationBigna JJR, Noubiap JJN, Asangbeh SL, Um LN, Simé PSD, Temfack E, et al. Abstracts reporting of HIV/AIDS randomized controlled trials in general medicine and infectious diseases journals: completeness to date and improvement in the quality since CONSORT extension for abstracts. BMC Medical Research Methodology. 2016;16(1):174 - 177. http://hdl.handle.net/11427/34314.en_ZA
dc.language.isoeng
dc.publisher.departmentDepartment of Medicine
dc.publisher.facultyFaculty of Health Sciences
dc.sourceBMC Medical Research Methodology
dc.source.journalissue1
dc.source.journalvolume16
dc.source.pagination174 - 177
dc.source.urihttps://dx.doi.org/10.1186/s12874-016-0243-y
dc.subject.otherAIDS
dc.subject.otherAbstract
dc.subject.otherCONSORT
dc.subject.otherHIV
dc.subject.otherRandomized controlled trial
dc.subject.otherSystematic review
dc.titleAbstracts reporting of HIV/AIDS randomized controlled trials in general medicine and infectious diseases journals: completeness to date and improvement in the quality since CONSORT extension for abstracts
dc.typeJournal Article
uct.type.publicationResearch
uct.type.resourceJournal Article
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