Sutureless adult voluntary male circumcision with topical anesthetic: a randomized field trial of Unicirc, a single-use surgical instrument

Simple item page
dc.contributor.authorShenje, Justinen_ZA
dc.contributor.authorMillard, Peter Sen_ZA
dc.date.accessioned2016-10-31T07:38:07Z
dc.date.available2016-10-31T07:38:07Z
dc.date.issued2016en_ZA
dc.description.abstractIntroduction The World Health Organization has solicited rapid and minimally invasive techniques to facilitate scale-up of voluntary medical male circumcision (VMMC). Study design Non-blinded randomized controlled field trial with 2:1 allocation ratio. Participants 75 adult male volunteers. Setting Outpatient primary care clinic. Intervention Open surgical circumcision under local anesthetic with suturing vs. Unicirc disposable instrument under topical anesthetic and wound sealing with cyanoacrylate tissue adhesive. Primary Outcome Intraoperative duration. Secondary Outcomes Intraoperative and postoperative pain; adverse events; time to healing; patient satisfaction; cosmetic result. RESULTS: The intraoperative time was less with the Unicirc technique (median 12 vs. 25 min, p < 0.001). Wound healing and cosmetic results were superior in the Unicirc group. Adverse events were similar in both groups. CONCLUSIONS: VMMC with Unicirc under topical anesthetic and wound sealing with cyanoacrylate tissue adhesive is rapid, heals by primary intention with superior cosmetic results, and is potentially safer and more cost-effective than open surgical VMMC. Trial Registration Clinicaltrials.gov NCT02443792en_ZA
dc.identifier.apacitationShenje, J., & Millard, P. S. (2016). Sutureless adult voluntary male circumcision with topical anesthetic: a randomized field trial of Unicirc, a single-use surgical instrument. <i>PLoS One</i>, http://hdl.handle.net/11427/22358en_ZA
dc.identifier.chicagocitationShenje, Justin, and Peter S Millard "Sutureless adult voluntary male circumcision with topical anesthetic: a randomized field trial of Unicirc, a single-use surgical instrument." <i>PLoS One</i> (2016) http://hdl.handle.net/11427/22358en_ZA
dc.identifier.citationShenje, J., & Millard, P. S. (2016). Sutureless adult voluntary male circumcision with topical anesthetic: a randomized field trial of Unicirc, a single-use surgical instrument. PloS one, 11(6), e0157065. doi:10.1371/journal.pone.0157065en_ZA
dc.identifier.ris TY - Journal Article AU - Shenje, Justin AU - Millard, Peter S AB - Introduction The World Health Organization has solicited rapid and minimally invasive techniques to facilitate scale-up of voluntary medical male circumcision (VMMC). Study design Non-blinded randomized controlled field trial with 2:1 allocation ratio. Participants 75 adult male volunteers. Setting Outpatient primary care clinic. Intervention Open surgical circumcision under local anesthetic with suturing vs. Unicirc disposable instrument under topical anesthetic and wound sealing with cyanoacrylate tissue adhesive. Primary Outcome Intraoperative duration. Secondary Outcomes Intraoperative and postoperative pain; adverse events; time to healing; patient satisfaction; cosmetic result. RESULTS: The intraoperative time was less with the Unicirc technique (median 12 vs. 25 min, p < 0.001). Wound healing and cosmetic results were superior in the Unicirc group. Adverse events were similar in both groups. CONCLUSIONS: VMMC with Unicirc under topical anesthetic and wound sealing with cyanoacrylate tissue adhesive is rapid, heals by primary intention with superior cosmetic results, and is potentially safer and more cost-effective than open surgical VMMC. Trial Registration Clinicaltrials.gov NCT02443792 DA - 2016 DB - OpenUCT DO - 10.1371/journal.pone.0157065 DP - University of Cape Town J1 - PLoS One LK - https://open.uct.ac.za PB - University of Cape Town PY - 2016 T1 - Sutureless adult voluntary male circumcision with topical anesthetic: a randomized field trial of Unicirc, a single-use surgical instrument TI - Sutureless adult voluntary male circumcision with topical anesthetic: a randomized field trial of Unicirc, a single-use surgical instrument UR - http://hdl.handle.net/11427/22358 ER - en_ZA
dc.identifier.urihttp://dx.doi.org/10.1371/journal.pone.0157065en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/22358
dc.identifier.vancouvercitationShenje J, Millard PS. Sutureless adult voluntary male circumcision with topical anesthetic: a randomized field trial of Unicirc, a single-use surgical instrument. PLoS One. 2016; http://hdl.handle.net/11427/22358.en_ZA
dc.language.isoengen_ZA
dc.publisherPublic Library of Scienceen_ZA
dc.publisher.departmentInstitute of Infectious Disease and Molecular Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en_ZA
dc.rights.holder© 2016 Shenje, Millarden_ZA
dc.rights.urihttp://creativecommons.org/licenses/by/4.0en_ZA
dc.sourcePLoS Oneen_ZA
dc.source.urihttp://journals.plos.org/plosoneen_ZA
dc.subject.otherCircumcisionen_ZA
dc.subject.otherAdverse eventsen_ZA
dc.subject.otherSurgical and invasive medical proceduresen_ZA
dc.subject.otherPlastic surgery and reconstructive techniquesen_ZA
dc.subject.otherAnestheticsen_ZA
dc.subject.otherTissue repairen_ZA
dc.subject.otherMedical devices and equipmenten_ZA
dc.subject.otherHemorrhageen_ZA
dc.titleSutureless adult voluntary male circumcision with topical anesthetic: a randomized field trial of Unicirc, a single-use surgical instrumenten_ZA
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Shenje_Sutureless_Adult_Male_Circumcision_2016.pdf
Size:
599.2 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Journal Articles