Investigation of the antioxidant activity of phenolic compounds in cell culture systems

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dc.contributor.advisorBurton, Stephanie Gailen_ZA
dc.contributor.authorZwane, Eunice Nonhlanhlaen_ZA
dc.date.accessioned2015-01-13T04:00:46Z
dc.date.available2015-01-13T04:00:46Z
dc.date.issued2009en_ZA
dc.descriptionIncludes abstract.en_ZA
dc.descriptionIncludes bibliographical references (leaves 81-95).en_ZA
dc.description.abstractThis study focuses on newly synthesized polyphenolic compounds which were expected to be antioxidants in vivo. Antioxidants are compounds which at low concentrations can prevent or reduce the deleterious effects caused by reactive oxygen species (ROS) induced by UVA exposure of the skin. This study focuses on developing methods required to measure the effects of these synthesized compounds in ultraviolet radiation-exposed cultured skin cells. Biocatalytic synthesis of polyphenolic compounds was carried out using isolated enzymes, tyrosinase from Agaricus biosporus, and laccase from Trametes pubescens to produce oxidized oligomeric products.en_ZA
dc.identifier.apacitationZwane, E. N. (2009). <i>Investigation of the antioxidant activity of phenolic compounds in cell culture systems</i>. (Thesis). University of Cape Town ,Faculty of Engineering & the Built Environment ,Department of Chemical Engineering. Retrieved from http://hdl.handle.net/11427/12126en_ZA
dc.identifier.chicagocitationZwane, Eunice Nonhlanhla. <i>"Investigation of the antioxidant activity of phenolic compounds in cell culture systems."</i> Thesis., University of Cape Town ,Faculty of Engineering & the Built Environment ,Department of Chemical Engineering, 2009. http://hdl.handle.net/11427/12126en_ZA
dc.identifier.citationZwane, E. 2009. Investigation of the antioxidant activity of phenolic compounds in cell culture systems. University of Cape Town.en_ZA
dc.identifier.risTY - Thesis / Dissertation AU - Zwane, Eunice Nonhlanhla AB - This study focuses on newly synthesized polyphenolic compounds which were expected to be antioxidants in vivo. Antioxidants are compounds which at low concentrations can prevent or reduce the deleterious effects caused by reactive oxygen species (ROS) induced by UVA exposure of the skin. This study focuses on developing methods required to measure the effects of these synthesized compounds in ultraviolet radiation-exposed cultured skin cells. Biocatalytic synthesis of polyphenolic compounds was carried out using isolated enzymes, tyrosinase from Agaricus biosporus, and laccase from Trametes pubescens to produce oxidized oligomeric products. DA - 2009 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2009 T1 - Investigation of the antioxidant activity of phenolic compounds in cell culture systems TI - Investigation of the antioxidant activity of phenolic compounds in cell culture systems UR - http://hdl.handle.net/11427/12126 ER -en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/12126
dc.identifier.vancouvercitationZwane EN. Investigation of the antioxidant activity of phenolic compounds in cell culture systems. [Thesis]. University of Cape Town ,Faculty of Engineering & the Built Environment ,Department of Chemical Engineering, 2009 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/12126en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentCentre for Bioprocess Engineering Researchen_ZA
dc.publisher.facultyFaculty of Engineering and the Built Environment
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherBioprocess Engineeringen_ZA
dc.titleInvestigation of the antioxidant activity of phenolic compounds in cell culture systemsen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMScen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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