Effect of artemether-lumefantrine policy and improved vector control on malaria burden in KwaZulu-Natal, South Africa

Journal Article

2005

Permanent link to this Item
http://hdl.handle.net/11427/26422
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Barnes_Effect_artemether_2005.pdf (447.97 KB)
Authors
Barnes, Karen I
Durrheim, David N
White, Nicholas J
Sharp, Brian L
Little, Francesca
Jackson, Amanda
Mehta, Ushma
Allen, Elizabeth
Dlamini, Sicelo S
Tsoka, Joyce
Bredekamp, Barry
Mthembu, D Jotham
Journal Title

PLoS Medicine

Link to Journal
http://journals.plos.org/plosmedicine/
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Volume Title
Publisher
Publisher

University of Cape Town

Department
Department of Medicine
Faculty
Faculty of Health Sciences
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Abstract
Between 1995 and 2000, KwaZulu–Natal province, South Africa, experienced a marked increase in Plasmodium falciparum malaria, fuelled by pyrethroid and sulfadoxine-pyrimethamine resistance. In response, vector control was strengthened and artemether-lumefantrine (AL) was deployed in the first Ministry of Health artemisinin-based combination treatment policy in Africa. In South Africa, effective vector and parasite control had historically ensured low-intensity malaria transmission. Malaria is diagnosed definitively and treatment is provided free of charge in reasonably accessible public-sector health-care facilities.
Description

Reference:

Barnes, K. I., Durrheim, D. N., Little, F., Jackson, A., Mehta, U., Allen, E., ... & White, N. J. (2005). Effect of artemether-lumefantrine policy and improved vector control on malaria burden in KwaZulu–Natal, South Africa. PLoS medicine, 2(11), e330.

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