The utility of abdominal ultrasound in the diagnosis of paediatric abdominal tuberculosis: a single centre review
| dc.contributor.advisor | Kilborn, Tracy | |
| dc.contributor.advisor | Eley, Brian | |
| dc.contributor.author | Sood, Vishesh | |
| dc.date.accessioned | 2021-03-01T18:46:21Z | |
| dc.date.available | 2021-03-01T18:46:21Z | |
| dc.date.issued | 2020 | |
| dc.date.updated | 2021-03-01T12:24:15Z | |
| dc.description.abstract | Background: Childhood tuberculosis (TB) is a common disease worldwide, with an increased propensity for severe, disseminated disease in settings with a high burden of concomitant HIV infection. Ultrasound is commonly used in diagnosing abdominal TB, however the indications for its use are unclear and often vary amongst clinicians. Objective: In this study, we describe the findings of ultrasound examinations performed for suspected abdominal TB at a tertiary children's hospital and examine the variability in reporting patterns amongst radiologists performing these imaging investigations. Materials and methods: Ultrasound studies performed for “suspected abdominal TB” between 01 January 2013 – 31 December 2018 were reviewed. In studies reported as suggestive of abdominal TB, evidence of microbiologically confirmed disease was sought. Subsequently, a selection of images from these studies were independently reviewed by three paediatric radiologists to determine their level of agreement when interpreting imaging findings. Results: During the study period 1093 studies were performed for suspected abdominal TB, of which 166 (15%) had abnormal features suggestive of TB. Forty-seven percent of these patients (78/166) had microbiologically confirmed disease. The commonest reported features were lymphadenopathy, 77% (128/166) and splenic microabscesses, 55% (92/166) for which substantial inter-reader agreement was documented, Fleiss' kappa = 0.64 and 0.66 respectively. There was moderate inter-reader agreement in the diagnosis of abdominal TB among radiologists (Fleiss' kappa=0.47). Conclusion: Caution is advised when basing clinical decisions on ultrasound studies performed for suspected abdominal TB, as imaging features are non-specific and there is considerable variability in interpretation of studies among reporting radiologists. | |
| dc.identifier.apacitation | Sood, V. (2020). <i>The utility of abdominal ultrasound in the diagnosis of paediatric abdominal tuberculosis: a single centre review</i>. (). ,Faculty of Health Sciences ,Division of Radiology. Retrieved from http://hdl.handle.net/11427/33037 | en_ZA |
| dc.identifier.chicagocitation | Sood, Vishesh. <i>"The utility of abdominal ultrasound in the diagnosis of paediatric abdominal tuberculosis: a single centre review."</i> ., ,Faculty of Health Sciences ,Division of Radiology, 2020. http://hdl.handle.net/11427/33037 | en_ZA |
| dc.identifier.citation | Sood, V. 2020. The utility of abdominal ultrasound in the diagnosis of paediatric abdominal tuberculosis: a single centre review. . ,Faculty of Health Sciences ,Division of Radiology. http://hdl.handle.net/11427/33037 | en_ZA |
| dc.identifier.ris | TY - Master Thesis AU - Sood, Vishesh AB - Background: Childhood tuberculosis (TB) is a common disease worldwide, with an increased propensity for severe, disseminated disease in settings with a high burden of concomitant HIV infection. Ultrasound is commonly used in diagnosing abdominal TB, however the indications for its use are unclear and often vary amongst clinicians. Objective: In this study, we describe the findings of ultrasound examinations performed for suspected abdominal TB at a tertiary children's hospital and examine the variability in reporting patterns amongst radiologists performing these imaging investigations. Materials and methods: Ultrasound studies performed for “suspected abdominal TB” between 01 January 2013 – 31 December 2018 were reviewed. In studies reported as suggestive of abdominal TB, evidence of microbiologically confirmed disease was sought. Subsequently, a selection of images from these studies were independently reviewed by three paediatric radiologists to determine their level of agreement when interpreting imaging findings. Results: During the study period 1093 studies were performed for suspected abdominal TB, of which 166 (15%) had abnormal features suggestive of TB. Forty-seven percent of these patients (78/166) had microbiologically confirmed disease. The commonest reported features were lymphadenopathy, 77% (128/166) and splenic microabscesses, 55% (92/166) for which substantial inter-reader agreement was documented, Fleiss' kappa = 0.64 and 0.66 respectively. There was moderate inter-reader agreement in the diagnosis of abdominal TB among radiologists (Fleiss' kappa=0.47). Conclusion: Caution is advised when basing clinical decisions on ultrasound studies performed for suspected abdominal TB, as imaging features are non-specific and there is considerable variability in interpretation of studies among reporting radiologists. DA - 2020_ DB - OpenUCT DP - University of Cape Town KW - Radiodiagnosis LK - https://open.uct.ac.za PY - 2020 T1 - The utility of abdominal ultrasound in the diagnosis of paediatric abdominal tuberculosis: a single centre review TI - The utility of abdominal ultrasound in the diagnosis of paediatric abdominal tuberculosis: a single centre review UR - http://hdl.handle.net/11427/33037 ER - | en_ZA |
| dc.identifier.uri | http://hdl.handle.net/11427/33037 | |
| dc.identifier.vancouvercitation | Sood V. The utility of abdominal ultrasound in the diagnosis of paediatric abdominal tuberculosis: a single centre review. []. ,Faculty of Health Sciences ,Division of Radiology, 2020 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/33037 | en_ZA |
| dc.language.rfc3066 | eng | |
| dc.publisher.department | Division of Radiology | |
| dc.publisher.faculty | Faculty of Health Sciences | |
| dc.subject | Radiodiagnosis | |
| dc.title | The utility of abdominal ultrasound in the diagnosis of paediatric abdominal tuberculosis: a single centre review | |
| dc.type | Master Thesis | |
| dc.type.qualificationlevel | Masters | |
| dc.type.qualificationlevel | MMed |