Outcomes of patients admitted with acute coronary syndrome to a district level hospital in a lower to middle income country

dc.contributor.advisorVan Der Schyff, Nasief
dc.contributor.advisorEngel, Mark
dc.contributor.authorGovender, Kamini
dc.date.accessioned2025-11-21T13:03:48Z
dc.date.available2025-11-21T13:03:48Z
dc.date.issued2025
dc.date.updated2025-11-21T13:00:19Z
dc.description.abstractBackground: Acute coronary syndrome (ACS) has become a leading cause of death in low-and middle-income countries. There is a lack of data regarding the outcomes of ACS in Africa. This study aims to assess the outcomes of ACS patients admitted to a resource-limited district hospital in Cape Town, South Africa. Methods: We conducted a retrospective observational study of patients admitted with ACS to the Department of Medicine at Victoria Hospital, Cape Town, from the 1 st September 2020 to 30 November 2020. Results: Eighty eight patients with a diagnosis of ACS was admitted, of who 52 had NSTEMI/UAP and 36 patients had STEMI. The median age was 60 years, with a male predominance of 61.36%. The major risk factors for CAD were hypertension and smoking. The overall 1-month, 6-month, and 12-month mortality rates for our cohort were 4%, 17%, and 19%, respectively. Patients that received coronary intervention (thrombolytics/PCI/CABG) had better outcomes than in those who were managed conservatively. Conclusion: This study describes the experience of ACS management in a resource-limited public hospital in Cape Town, South Africa. Our patients had multiple cardiovascular risk factors with a higher mortality than published data. The lack of receiving coronary intervention was associated with worse outcomes.
dc.identifier.apacitationGovender, K. (2025). <i>Outcomes of patients admitted with acute coronary syndrome to a district level hospital in a lower to middle income country</i>. (). University of Cape Town ,Faculty of Health Sciences ,Department of Medicine. Retrieved from http://hdl.handle.net/11427/42299en_ZA
dc.identifier.chicagocitationGovender, Kamini. <i>"Outcomes of patients admitted with acute coronary syndrome to a district level hospital in a lower to middle income country."</i> ., University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2025. http://hdl.handle.net/11427/42299en_ZA
dc.identifier.citationGovender, K. 2025. Outcomes of patients admitted with acute coronary syndrome to a district level hospital in a lower to middle income country. . University of Cape Town ,Faculty of Health Sciences ,Department of Medicine. http://hdl.handle.net/11427/42299en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Govender, Kamini AB - Background: Acute coronary syndrome (ACS) has become a leading cause of death in low-and middle-income countries. There is a lack of data regarding the outcomes of ACS in Africa. This study aims to assess the outcomes of ACS patients admitted to a resource-limited district hospital in Cape Town, South Africa. Methods: We conducted a retrospective observational study of patients admitted with ACS to the Department of Medicine at Victoria Hospital, Cape Town, from the 1 st September 2020 to 30 November 2020. Results: Eighty eight patients with a diagnosis of ACS was admitted, of who 52 had NSTEMI/UAP and 36 patients had STEMI. The median age was 60 years, with a male predominance of 61.36%. The major risk factors for CAD were hypertension and smoking. The overall 1-month, 6-month, and 12-month mortality rates for our cohort were 4%, 17%, and 19%, respectively. Patients that received coronary intervention (thrombolytics/PCI/CABG) had better outcomes than in those who were managed conservatively. Conclusion: This study describes the experience of ACS management in a resource-limited public hospital in Cape Town, South Africa. Our patients had multiple cardiovascular risk factors with a higher mortality than published data. The lack of receiving coronary intervention was associated with worse outcomes. DA - 2025 DB - OpenUCT DP - University of Cape Town KW - acute coronary syndrome KW - outcomes KW - ischemic heart disease KW - mortality KW - MACE LK - https://open.uct.ac.za PB - University of Cape Town PY - 2025 T1 - Outcomes of patients admitted with acute coronary syndrome to a district level hospital in a lower to middle income country TI - Outcomes of patients admitted with acute coronary syndrome to a district level hospital in a lower to middle income country UR - http://hdl.handle.net/11427/42299 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/42299
dc.identifier.vancouvercitationGovender K. Outcomes of patients admitted with acute coronary syndrome to a district level hospital in a lower to middle income country. []. University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2025 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/42299en_ZA
dc.language.isoen
dc.language.rfc3066eng
dc.publisher.departmentDepartment of Medicine
dc.publisher.facultyFaculty of Health Sciences
dc.publisher.institutionUniversity of Cape Town
dc.subjectacute coronary syndrome
dc.subjectoutcomes
dc.subjectischemic heart disease
dc.subjectmortality
dc.subjectMACE
dc.titleOutcomes of patients admitted with acute coronary syndrome to a district level hospital in a lower to middle income country
dc.typeThesis / Dissertation
dc.type.qualificationlevelMasters
dc.type.qualificationlevelMMed
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