Interactions between HIV and hepatitis B and C

Journal Article

2003

Authors
Journal Title

South African Journal for Continuing Medical Education

Journal ISSN
Volume Title
Publisher

Health and Medical Publishing Group

Publisher

University of Cape Town

Series
Abstract
HIV shares routes of transmission with the chronic hepatitis viruses B and C. All three can be transmitted by blood products or needle sharing in intravenous drug users. HIV and hepatitis B can also be transmitted sexually and vertically (hepatitis C is seldom transmitted by these routes). Therefore it is not surprising that co-infection with HIV and hepatitis B or C is common. Co-infection particularly affects hepatitis virus infections. There appears to be no effect of either hepatitis B or C on the natural history of HIV, but co-infection complicates the use of highly active antiretroviral therapy (HAART). Complications of chronic viral hepatitis have emerged as leading causes of morbidity and mortality in HIV-infected patients in regions where there is ready access to HAART. Medical therapy of chronic hepatitis B and C is complex and expensive, and should be undertaken only by specialists in the field.
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