Treatment outcomes of young patients with invasive breast cancer treated radically at Groote Schuur Hospital from 2013-2017: A single centre study
| dc.contributor.advisor | Tselane, Thebe | |
| dc.contributor.advisor | Hunter, Alistair | |
| dc.contributor.author | Tangane, Gomolemo | |
| dc.date.accessioned | 2023-04-20T17:13:47Z | |
| dc.date.available | 2023-04-20T17:13:47Z | |
| dc.date.issued | 2022 | |
| dc.date.updated | 2023-04-20T17:13:20Z | |
| dc.description.abstract | Treatment outcomes of young patients with invasive breast cancer treated radically at Groote Schuur Hospital from 2013 to 2017: A single centre study Background: Breast cancer is the leading cause of cancer- related deaths globally, and the commonest cancer in women under 40 years. There is currently a lack of data relating to treatment outcomes of young women with breast cancer particularly in low-and middle-income countries. Aim: This study aims to evaluate the treatment outcomes of young patients (under 40 years) treated radically for invasive breast cancer in a low-and middle-income setting. Settings: Groote Schuur Hospital, Cape Town, South Africa Methods: A retrospective review of 101 women under 40 years, with invasive breast cancer treated radically, between 2013 and 2017 was conducted. Patient characteristics, tumour characteristics, disease stage, treatment, and follow-up were recorded. Primary objectives included evaluating overall and disease free survival, and analysing recurrence patterns and clinicopathological features. Results: The five-year overall and disease free survival for the entire cohort was 77% and 51%, respectively. Five-year overall survival by molecular subtype showed that Luminal A had the best survival, while triple negative breast cancer had the worst overall survival. Conclusion: Young women with breast cancer have poor survival outcomes despite early presentation. There is limited data regarding breast cancer treatment outcomes in patients under forty years. | |
| dc.identifier.apacitation | Tangane, G. (2022). <i>Treatment outcomes of young patients with invasive breast cancer treated radically at Groote Schuur Hospital from 2013-2017: A single centre study</i>. (). ,Faculty of Health Sciences ,Division of Radiology. Retrieved from http://hdl.handle.net/11427/37808 | en_ZA |
| dc.identifier.chicagocitation | Tangane, Gomolemo. <i>"Treatment outcomes of young patients with invasive breast cancer treated radically at Groote Schuur Hospital from 2013-2017: A single centre study."</i> ., ,Faculty of Health Sciences ,Division of Radiology, 2022. http://hdl.handle.net/11427/37808 | en_ZA |
| dc.identifier.citation | Tangane, G. 2022. Treatment outcomes of young patients with invasive breast cancer treated radically at Groote Schuur Hospital from 2013-2017: A single centre study. . ,Faculty of Health Sciences ,Division of Radiology. http://hdl.handle.net/11427/37808 | en_ZA |
| dc.identifier.ris | TY - Master Thesis AU - Tangane, Gomolemo AB - Treatment outcomes of young patients with invasive breast cancer treated radically at Groote Schuur Hospital from 2013 to 2017: A single centre study Background: Breast cancer is the leading cause of cancer- related deaths globally, and the commonest cancer in women under 40 years. There is currently a lack of data relating to treatment outcomes of young women with breast cancer particularly in low-and middle-income countries. Aim: This study aims to evaluate the treatment outcomes of young patients (under 40 years) treated radically for invasive breast cancer in a low-and middle-income setting. Settings: Groote Schuur Hospital, Cape Town, South Africa Methods: A retrospective review of 101 women under 40 years, with invasive breast cancer treated radically, between 2013 and 2017 was conducted. Patient characteristics, tumour characteristics, disease stage, treatment, and follow-up were recorded. Primary objectives included evaluating overall and disease free survival, and analysing recurrence patterns and clinicopathological features. Results: The five-year overall and disease free survival for the entire cohort was 77% and 51%, respectively. Five-year overall survival by molecular subtype showed that Luminal A had the best survival, while triple negative breast cancer had the worst overall survival. Conclusion: Young women with breast cancer have poor survival outcomes despite early presentation. There is limited data regarding breast cancer treatment outcomes in patients under forty years. DA - 2022 DB - OpenUCT DP - University of Cape Town KW - breast cancer young women KW - breast cancer Africa KW - breast cancer South Africa KW - breast cancer survival KW - breast cancer under 40 years KW - breast cancer treatment outcomes KW - low and middle-income countries LK - https://open.uct.ac.za PY - 2022 T1 - Treatment outcomes of young patients with invasive breast cancer treated radically at Groote Schuur Hospital from 2013-2017: A single centre study TI - Treatment outcomes of young patients with invasive breast cancer treated radically at Groote Schuur Hospital from 2013-2017: A single centre study UR - http://hdl.handle.net/11427/37808 ER - | en_ZA |
| dc.identifier.uri | http://hdl.handle.net/11427/37808 | |
| dc.identifier.vancouvercitation | Tangane G. Treatment outcomes of young patients with invasive breast cancer treated radically at Groote Schuur Hospital from 2013-2017: A single centre study. []. ,Faculty of Health Sciences ,Division of Radiology, 2022 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/37808 | en_ZA |
| dc.language.rfc3066 | eng | |
| dc.publisher.department | Division of Radiology | |
| dc.publisher.faculty | Faculty of Health Sciences | |
| dc.subject | breast cancer young women | |
| dc.subject | breast cancer Africa | |
| dc.subject | breast cancer South Africa | |
| dc.subject | breast cancer survival | |
| dc.subject | breast cancer under 40 years | |
| dc.subject | breast cancer treatment outcomes | |
| dc.subject | low and middle-income countries | |
| dc.title | Treatment outcomes of young patients with invasive breast cancer treated radically at Groote Schuur Hospital from 2013-2017: A single centre study | |
| dc.type | Master Thesis | |
| dc.type.qualificationlevel | Masters | |
| dc.type.qualificationlevel | MMed |