Synthesis, characterization and anticancer studies of multinuclear ruthenium(II) arene complexes based on a dendritic scaffold

Master Thesis

2010

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University of Cape Town

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A series of monodentate (N-) and chelating bidentate (N,N-, N,O-), monomeric and dendritic ligands based on a poly(propyleneimine) dendrimer scaffold were synthesized via Schiff base condensation reactions of the relevant amine and appropriate aldehydes. These reactions yielded air- and moisture-stable oils or solids. These ligands contained pyridyl-imine moieties and salicylaldimine moieties. These compounds were isolated in good yields and characterized using standard spectroscopic and spectrometric, analytical techniques.
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