Evaluation of serum prolidase activity as a marker for liver fibrosis in suspected liver disease

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dc.contributor.advisorPillay, Tahir Sen_ZA
dc.contributor.authorStanfliet, John Christianen_ZA
dc.date.accessioned2015-01-01T12:15:21Z
dc.date.available2015-01-01T12:15:21Z
dc.date.issued2011en_ZA
dc.descriptionIncludes bibliographical references (leaves 67-72).en_ZA
dc.description.abstractLiver dysfunction is common, often unrecognised and likely to increase in incidence in the population in parallel with the obesity and attendant type 2 diabetes mellitus epidemics. Liver fibrosis is a significant finding in liver pathology as it imparts important clinical staging and prognostic information, is a risk marker of adverse clinical outcome yet, even if advanced, is capable of reversal. Histological examination of liver biopsy material is the reference standard in the assessment of liver fibrosis, but it is impractical to biopsy all patients suspected of having liver disease. Serumprolidase is among novel biomarkers that have been described in diagnosing and/or staging liver fibrosis. This study evaluated the measurement and the diagnostic accuracy of serumprolidase in determining the potential presence and degree of liver fibrosis compared with liver biopsy.en_ZA
dc.identifier.apacitationStanfliet, J. C. (2011). <i>Evaluation of serum prolidase activity as a marker for liver fibrosis in suspected liver disease</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Chemical Pathology. Retrieved from http://hdl.handle.net/11427/10805en_ZA
dc.identifier.chicagocitationStanfliet, John Christian. <i>"Evaluation of serum prolidase activity as a marker for liver fibrosis in suspected liver disease."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Chemical Pathology, 2011. http://hdl.handle.net/11427/10805en_ZA
dc.identifier.citationStanfliet, J. 2011. Evaluation of serum prolidase activity as a marker for liver fibrosis in suspected liver disease. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Stanfliet, John Christian AB - Liver dysfunction is common, often unrecognised and likely to increase in incidence in the population in parallel with the obesity and attendant type 2 diabetes mellitus epidemics. Liver fibrosis is a significant finding in liver pathology as it imparts important clinical staging and prognostic information, is a risk marker of adverse clinical outcome yet, even if advanced, is capable of reversal. Histological examination of liver biopsy material is the reference standard in the assessment of liver fibrosis, but it is impractical to biopsy all patients suspected of having liver disease. Serumprolidase is among novel biomarkers that have been described in diagnosing and/or staging liver fibrosis. This study evaluated the measurement and the diagnostic accuracy of serumprolidase in determining the potential presence and degree of liver fibrosis compared with liver biopsy. DA - 2011 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2011 T1 - Evaluation of serum prolidase activity as a marker for liver fibrosis in suspected liver disease TI - Evaluation of serum prolidase activity as a marker for liver fibrosis in suspected liver disease UR - http://hdl.handle.net/11427/10805 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/10805
dc.identifier.vancouvercitationStanfliet JC. Evaluation of serum prolidase activity as a marker for liver fibrosis in suspected liver disease. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Chemical Pathology, 2011 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/10805en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDivision of Chemical Pathologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherChemical Pathologyen_ZA
dc.titleEvaluation of serum prolidase activity as a marker for liver fibrosis in suspected liver diseaseen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMMeden_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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