Paediatric out-of-theatre procedural sedation at a tertiary children's hospital: A prospective observational study

dc.contributor.advisorGray, Rebecca
dc.contributor.advisorWilson, Graeme
dc.contributor.authorLapere, Cherese
dc.date.accessioned2022-03-04T08:36:19Z
dc.date.available2022-03-04T08:36:19Z
dc.date.issued2021
dc.date.updated2022-03-01T09:01:49Z
dc.description.abstractBackground: This tertiary referral centre is one the largest paediatric hospitals in Africa. Despite an increasing number of surgical and diagnostic procedures being performed annually, a formal out-of-theatre sedation service does not exist. Procedural sedation and analgesia (PSA) is an important adjunct in behavioural management for invasive procedures in children. Objective: A prospective, observational study was performed at RCWMCH, aimed primarily at defining the number of cases of PSA performed outside the operating theatre. Methods: Data was collected from all procedural out-of-theatre sedations performed over a period of three months, including ward patients and out-patient departments. All children < 13 years of age were included. Results: A total of 639 sedations were performed. Of these sedations, 288 (45.0%) paper responses were captured and analysed. The reported incidence of desaturation was 4.2% (12/288), laryngospasm 0.3% (1/288) and nausea and vomiting 2.4% (6/288). Three cases required conversion to general anaesthetic, and three cases were abandoned due to inadequate sedation. In 16.3% (47/288) of cases the clinician was an operator sedationist (the same person performing the sedation and the procedure). In 90.6% of cases the intravenous route was utilized, with dexmedetomidine, ketamine and propofol being the three most commonly used agents. Conclusion: 639 PSA events were recorded in 3 months. The 288 events analysed were safely performed with minimal serious reported events. These results compare favourably with international studies and provide quantitative evidence as a prelude to setting up a dedicated sedation service at our facility.
dc.identifier.apacitationLapere, C. (2021). <i>Paediatric out-of-theatre procedural sedation at a tertiary children's hospital: A prospective observational study</i>. (). ,Faculty of Health Sciences ,Department of Anaesthesia and Perioperative Medicine. Retrieved from http://hdl.handle.net/11427/35905en_ZA
dc.identifier.chicagocitationLapere, Cherese. <i>"Paediatric out-of-theatre procedural sedation at a tertiary children's hospital: A prospective observational study."</i> ., ,Faculty of Health Sciences ,Department of Anaesthesia and Perioperative Medicine, 2021. http://hdl.handle.net/11427/35905en_ZA
dc.identifier.citationLapere, C. 2021. Paediatric out-of-theatre procedural sedation at a tertiary children's hospital: A prospective observational study. . ,Faculty of Health Sciences ,Department of Anaesthesia and Perioperative Medicine. http://hdl.handle.net/11427/35905en_ZA
dc.identifier.ris TY - Master Thesis AU - Lapere, Cherese AB - Background: This tertiary referral centre is one the largest paediatric hospitals in Africa. Despite an increasing number of surgical and diagnostic procedures being performed annually, a formal out-of-theatre sedation service does not exist. Procedural sedation and analgesia (PSA) is an important adjunct in behavioural management for invasive procedures in children. Objective: A prospective, observational study was performed at RCWMCH, aimed primarily at defining the number of cases of PSA performed outside the operating theatre. Methods: Data was collected from all procedural out-of-theatre sedations performed over a period of three months, including ward patients and out-patient departments. All children < 13 years of age were included. Results: A total of 639 sedations were performed. Of these sedations, 288 (45.0%) paper responses were captured and analysed. The reported incidence of desaturation was 4.2% (12/288), laryngospasm 0.3% (1/288) and nausea and vomiting 2.4% (6/288). Three cases required conversion to general anaesthetic, and three cases were abandoned due to inadequate sedation. In 16.3% (47/288) of cases the clinician was an operator sedationist (the same person performing the sedation and the procedure). In 90.6% of cases the intravenous route was utilized, with dexmedetomidine, ketamine and propofol being the three most commonly used agents. Conclusion: 639 PSA events were recorded in 3 months. The 288 events analysed were safely performed with minimal serious reported events. These results compare favourably with international studies and provide quantitative evidence as a prelude to setting up a dedicated sedation service at our facility. DA - 2021_ DB - OpenUCT DP - University of Cape Town KW - Anaesthesiology and Perioperative Medicine LK - https://open.uct.ac.za PY - 2021 T1 - Paediatric out-of-theatre procedural sedation at a tertiary children's hospital: A prospective observational study TI - Paediatric out-of-theatre procedural sedation at a tertiary children's hospital: A prospective observational study UR - http://hdl.handle.net/11427/35905 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/35905
dc.identifier.vancouvercitationLapere C. Paediatric out-of-theatre procedural sedation at a tertiary children's hospital: A prospective observational study. []. ,Faculty of Health Sciences ,Department of Anaesthesia and Perioperative Medicine, 2021 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/35905en_ZA
dc.language.rfc3066eng
dc.publisher.departmentDepartment of Anaesthesia and Perioperative Medicine
dc.publisher.facultyFaculty of Health Sciences
dc.subjectAnaesthesiology and Perioperative Medicine
dc.titlePaediatric out-of-theatre procedural sedation at a tertiary children's hospital: A prospective observational study
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationlevelMMed
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