Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease

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dc.contributor.advisorGreenberg, Jacquieen_ZA
dc.contributor.advisorGoliath, Reneen_ZA
dc.contributor.authorScholefield, Janineen_ZA
dc.date.accessioned2014-07-29T09:10:20Z
dc.date.available2014-07-29T09:10:20Z
dc.date.issued2005en_ZA
dc.descriptionIncludes bibliographical references (leaves 113-124).
dc.description.abstractThe primary aim of this study was to investigate the origins of the HD mutation in South Africa (SA) by constructing a single nucleotide polymorphism (SNP) haplotype around the IT15 gene and to determine how many haplotypes there are in SA. Haplotypes were created by genotyping 6 SNPs in a total of 15 HD families. These families were comprised of seven Caucasian, 6 Mixed Ancestry and two Black African families.en_ZA
dc.identifier.apacitationScholefield, J. (2005). <i>Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Medicine. Retrieved from http://hdl.handle.net/11427/3460en_ZA
dc.identifier.chicagocitationScholefield, Janine. <i>"Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2005. http://hdl.handle.net/11427/3460en_ZA
dc.identifier.citationScholefield, J. 2005. Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Scholefield, Janine AB - The primary aim of this study was to investigate the origins of the HD mutation in South Africa (SA) by constructing a single nucleotide polymorphism (SNP) haplotype around the IT15 gene and to determine how many haplotypes there are in SA. Haplotypes were created by genotyping 6 SNPs in a total of 15 HD families. These families were comprised of seven Caucasian, 6 Mixed Ancestry and two Black African families. DA - 2005 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2005 T1 - Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease TI - Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease UR - http://hdl.handle.net/11427/3460 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/3460
dc.identifier.vancouvercitationScholefield J. Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2005 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/3460en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherMedicineen_ZA
dc.titleDetailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington diseaseen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMScen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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