Associations of severe hyperlactataemia and lactic acidosis in HIV-infected patients receiving antiretroviral theraphy

Master Thesis

2007

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http://hdl.handle.net/11427/7438
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thesis_hsf_2007_osler_m.pdf (3.62 MB)
Authors
Osler, Meg
Supervisors
Boulle, Andrew
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University of Cape Town

Department
Department of Public Health and Family Medicine
Faculty
Faculty of Health Sciences
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Abstract
Severe symptomatic hyperlactataemia and lactic acidosis (SHLA) are life-threatening events that are occurring at increasing incidence levels in South Africa. Globally, the rise in SHLA cases is closely correlated to the increased accessibility of anti retroviral (ARV) medication for human immunodeficiency virus (HIV). Although hyperlactataemia and lactic acidosis were once thought of as rare conditions, they are now being recognized as important concerns when administering antiretroviral therapy. A better understanding of the risk factors for SHLA is important in combating the morbidity and mortality associated with such an adverse event.
Description

Includes bibliographical references (leaves 67-70).

Reference:

Osler, M. 2007. Associations of severe hyperlactataemia and lactic acidosis in HIV-infected patients receiving antiretroviral theraphy. University of Cape Town.

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