Do proton pump inhibitors reduce the incidence of pharyngocutaneous fistulae following total laryngectomy?
Master Thesis
2013
Permanent link to this Item
Authors
Supervisors
Journal Title
Link to Journal
Journal ISSN
Volume Title
Publisher
Publisher
University of Cape Town
Department
Faculty
License
Series
Abstract
Pharyngocutaneous fistula is a common complication of total laryngectomy. We hypothesised that perioperative proton pump inhibitor (PPI) treatment could reduce the incidence of pharyngocutaneous fistulae. This prospective placebo-controlled double-blind randomised controlled trial compared PPI treatment (14 days enteral omeprazole) with a placebo in patients undergoing primary total laryngectomy. The incidence of pharyngocutaneous fistula was recorded.
Description
Includes abstract.
Includes bibliographical references.
Keywords
Reference:
Stephenson, K. 2013. Do proton pump inhibitors reduce the incidence of pharyngocutaneous fistulae following total laryngectomy?. University of Cape Town.