Helicobacter pylori Infection: Antibiotic Resistance and Solutions for Effective Management in Africa

dc.contributor.authorSetshedi, Mashiko
dc.contributor.authorSmith, Stella I.
dc.date.accessioned2023-09-13T10:23:17Z
dc.date.available2023-09-13T10:23:17Z
dc.date.issued2023-05-26
dc.date.updated2023-06-27T13:21:53Z
dc.description.abstractHelicobacter pylori. pylori infection is ubiquitous worldwide, with prevalence rates of greater than 70% in Africa. Symptomatic patients present with foregut gastrointestinal symptoms which can be readily diagnosed with standardized non-invasive or invasive tests. The biggest challenge, however, is in the management of this condition with rising antimicrobial resistance rates to most of the antibiotics recommended for therapy. This is a problem worldwide, but more specifically in Africa, where the socio-economic and political climate is such that eradication of this organism seems impossible. Furthermore, the recommended antimicrobial susceptibility testing for drug resistance is not widely available in Africa due to the lack of infrastructural as well as human resources. With the widespread unregulated use of antibiotics in some parts of Africa, the figures of antimicrobial resistance are likely to soar. In the face of these significant challenges, this ‘perspectives’ article aims to address the issue of antimicrobial resistance in Africa, by providing achievable and targeted goals to curb the spread of infection and rising antimicrobial resistance.
dc.identifierdoi: 10.3390/antibiotics12060969
dc.identifier.apacitationSetshedi, M., & Smith, Stella I. (2023). Helicobacter pylori Infection: Antibiotic Resistance and Solutions for Effective Management in Africa. <i>Antibiotics</i>, 12(6), 969. http://hdl.handle.net/11427/38579en_ZA
dc.identifier.chicagocitationSetshedi, Mashiko, and Stella I. Smith "Helicobacter pylori Infection: Antibiotic Resistance and Solutions for Effective Management in Africa." <i>Antibiotics</i> 12, 6. (2023): 969. http://hdl.handle.net/11427/38579en_ZA
dc.identifier.citationSetshedi, M. & Smith, Stella I. 2023. Helicobacter pylori Infection: Antibiotic Resistance and Solutions for Effective Management in Africa. <i>Antibiotics.</i> 12(6):969. http://hdl.handle.net/11427/38579en_ZA
dc.identifier.ris TY - Journal Article AU - Setshedi, Mashiko AU - Smith, Stella I. AB - Helicobacter pylori. pylori infection is ubiquitous worldwide, with prevalence rates of greater than 70% in Africa. Symptomatic patients present with foregut gastrointestinal symptoms which can be readily diagnosed with standardized non-invasive or invasive tests. The biggest challenge, however, is in the management of this condition with rising antimicrobial resistance rates to most of the antibiotics recommended for therapy. This is a problem worldwide, but more specifically in Africa, where the socio-economic and political climate is such that eradication of this organism seems impossible. Furthermore, the recommended antimicrobial susceptibility testing for drug resistance is not widely available in Africa due to the lack of infrastructural as well as human resources. With the widespread unregulated use of antibiotics in some parts of Africa, the figures of antimicrobial resistance are likely to soar. In the face of these significant challenges, this &lsquo;perspectives&rsquo; article aims to address the issue of antimicrobial resistance in Africa, by providing achievable and targeted goals to curb the spread of infection and rising antimicrobial resistance. DA - 2023-05-26 DB - OpenUCT DP - University of Cape Town IS - 6 J1 - Antibiotics LK - https://open.uct.ac.za PY - 2023 T1 - Helicobacter pylori Infection: Antibiotic Resistance and Solutions for Effective Management in Africa TI - Helicobacter pylori Infection: Antibiotic Resistance and Solutions for Effective Management in Africa UR - http://hdl.handle.net/11427/38579 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/38579
dc.identifier.vancouvercitationSetshedi M, Smith Stella I. Helicobacter pylori Infection: Antibiotic Resistance and Solutions for Effective Management in Africa. Antibiotics. 2023;12(6):969. http://hdl.handle.net/11427/38579.en_ZA
dc.publisherMultidisciplinary Digital Publishing Institute
dc.publisher.departmentMedicine
dc.publisher.facultyHealth Sciences
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceAntibiotics
dc.source.journalissue6
dc.source.journalvolume12
dc.source.pagination969
dc.source.urihttps://www.mdpi.com/journal/antibiotics
dc.titleHelicobacter pylori Infection: Antibiotic Resistance and Solutions for Effective Management in Africa
dc.typeJournal Article
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