Progress in the synthesis of stabilized glycoconjugate vaccine candidates against Neisseria meningitides group A

Master Thesis

2003

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University of Cape Town

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Abstract
Meningitis is the inflammation of the lining membranes of human brains and spinal cord. It is a deadly disease that has claimed millions of lives throughout the world in particular in developing countries. Neisseria meningitidis serogroup A is among the leading causative agents of meningitis in Sub-Saharan Africa. Its capsular polysaccharide antigen consists of a homopolymer of a-(1
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Includes bibliographical references.

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