Using the Medical Research Council framework for development and evaluation of complex interventions in a low resource setting to develop a theory-based treatment support intervention delivered via SMS text message to improve blood pressure control
| dc.contributor.author | Bobrow, Kirsten | |
| dc.contributor.author | Farmer, Andrew | |
| dc.contributor.author | Cishe, Nomazizi | |
| dc.contributor.author | Nwagi, Ntobeko | |
| dc.contributor.author | Namane, Mosedi | |
| dc.contributor.author | Brennan, Thomas P | |
| dc.contributor.author | Springer, David | |
| dc.contributor.author | Tarassenko, Lionel | |
| dc.contributor.author | Levitt, Naomi | |
| dc.date.accessioned | 2018-04-17T06:26:48Z | |
| dc.date.available | 2018-04-17T06:26:48Z | |
| dc.date.issued | 2018-01-23 | |
| dc.date.updated | 2018-04-09T15:05:10Z | |
| dc.description.abstract | Background: Several frameworks now exist to guide intervention development but there remains only limited evidence of their application to health interventions based around use of mobile phones or devices, particularly in a low-resource setting. We aimed to describe our experience of using the Medical Research Council (MRC) Framework on complex interventions to develop and evaluate an adherence support intervention for high blood pressure delivered by SMS text message. We further aimed to describe the developed intervention in line with reporting guidelines for a structured and systematic description. Methods: We used a non-sequential and flexible approach guided by the 2008 MRC Framework for the development and evaluation of complex interventions. Results: We reviewed published literature and established a multi-disciplinary expert group to guide the development process. We selected health psychology theory and behaviour change techniques that have been shown to be important in adherence and persistence with chronic medications. Semi-structured interviews and focus groups with various stakeholders identified ways in which treatment adherence could be supported and also identified key features of well-regarded messages: polite tone, credible information, contextualised, and endorsed by identifiable member of primary care facility staff. Direct and indirect user testing enabled us to refine the intervention including refining use of language and testing of interactive components. Conclusions: Our experience shows that using a formal intervention development process is feasible in a low-resource multi-lingual setting. The process enabled us to pre-test assumptions about the intervention and the evaluation process, allowing the improvement of both. Describing how a multi-component intervention was developed including standardised descriptions of content aimed to support behaviour change will enable comparison with other similar interventions and support development of new interventions. Even in low-resource settings, funders and policy-makers should provide researchers with time and resources for intervention development work and encourage evaluation of the entire design and testing process. Trial registration: The trial of the intervention is registered with South African National Clinical Trials Register number (SANCTR DOH-27-1212-386; 28/12/2012); Pan Africa Trial Register (PACTR201411000724141; 14/12/2013); ClinicalTrials. gov (NCT02019823; 24/12/2013). | |
| dc.identifier.apacitation | Bobrow, K., Farmer, A., Cishe, N., Nwagi, N., Namane, M., Brennan, T. P., ... Levitt, N. (2018). Using the Medical Research Council framework for development and evaluation of complex interventions in a low resource setting to develop a theory-based treatment support intervention delivered via SMS text message to improve blood pressure control. <i>BMC Health Services Research</i>, http://hdl.handle.net/11427/27789 | en_ZA |
| dc.identifier.chicagocitation | Bobrow, Kirsten, Andrew Farmer, Nomazizi Cishe, Ntobeko Nwagi, Mosedi Namane, Thomas P Brennan, David Springer, Lionel Tarassenko, and Naomi Levitt "Using the Medical Research Council framework for development and evaluation of complex interventions in a low resource setting to develop a theory-based treatment support intervention delivered via SMS text message to improve blood pressure control." <i>BMC Health Services Research</i> (2018) http://hdl.handle.net/11427/27789 | en_ZA |
| dc.identifier.citation | BMC Health Services Research. 2018 Jan 23;18(1):33 | |
| dc.identifier.ris | TY - Journal Article AU - Bobrow, Kirsten AU - Farmer, Andrew AU - Cishe, Nomazizi AU - Nwagi, Ntobeko AU - Namane, Mosedi AU - Brennan, Thomas P AU - Springer, David AU - Tarassenko, Lionel AU - Levitt, Naomi AB - Background: Several frameworks now exist to guide intervention development but there remains only limited evidence of their application to health interventions based around use of mobile phones or devices, particularly in a low-resource setting. We aimed to describe our experience of using the Medical Research Council (MRC) Framework on complex interventions to develop and evaluate an adherence support intervention for high blood pressure delivered by SMS text message. We further aimed to describe the developed intervention in line with reporting guidelines for a structured and systematic description. Methods: We used a non-sequential and flexible approach guided by the 2008 MRC Framework for the development and evaluation of complex interventions. Results: We reviewed published literature and established a multi-disciplinary expert group to guide the development process. We selected health psychology theory and behaviour change techniques that have been shown to be important in adherence and persistence with chronic medications. Semi-structured interviews and focus groups with various stakeholders identified ways in which treatment adherence could be supported and also identified key features of well-regarded messages: polite tone, credible information, contextualised, and endorsed by identifiable member of primary care facility staff. Direct and indirect user testing enabled us to refine the intervention including refining use of language and testing of interactive components. Conclusions: Our experience shows that using a formal intervention development process is feasible in a low-resource multi-lingual setting. The process enabled us to pre-test assumptions about the intervention and the evaluation process, allowing the improvement of both. Describing how a multi-component intervention was developed including standardised descriptions of content aimed to support behaviour change will enable comparison with other similar interventions and support development of new interventions. Even in low-resource settings, funders and policy-makers should provide researchers with time and resources for intervention development work and encourage evaluation of the entire design and testing process. Trial registration: The trial of the intervention is registered with South African National Clinical Trials Register number (SANCTR DOH-27-1212-386; 28/12/2012); Pan Africa Trial Register (PACTR201411000724141; 14/12/2013); ClinicalTrials. gov (NCT02019823; 24/12/2013). DA - 2018-01-23 DB - OpenUCT DO - 10.1186/s12913-017-2808-9 DP - University of Cape Town J1 - BMC Health Services Research LK - https://open.uct.ac.za PB - University of Cape Town PY - 2018 T1 - Using the Medical Research Council framework for development and evaluation of complex interventions in a low resource setting to develop a theory-based treatment support intervention delivered via SMS text message to improve blood pressure control TI - Using the Medical Research Council framework for development and evaluation of complex interventions in a low resource setting to develop a theory-based treatment support intervention delivered via SMS text message to improve blood pressure control UR - http://hdl.handle.net/11427/27789 ER - | en_ZA |
| dc.identifier.uri | http://dx.doi.org/10.1186/s12913-017-2808-9 | |
| dc.identifier.uri | http://hdl.handle.net/11427/27789 | |
| dc.identifier.vancouvercitation | Bobrow K, Farmer A, Cishe N, Nwagi N, Namane M, Brennan TP, et al. Using the Medical Research Council framework for development and evaluation of complex interventions in a low resource setting to develop a theory-based treatment support intervention delivered via SMS text message to improve blood pressure control. BMC Health Services Research. 2018; http://hdl.handle.net/11427/27789. | en_ZA |
| dc.language.iso | en | |
| dc.publisher | BioMed Central | |
| dc.publisher.department | Department of Public Health and Family Medicine | en_ZA |
| dc.publisher.faculty | Faculty of Health Sciences | en_ZA |
| dc.publisher.institution | University of Cape Town | |
| dc.rights.holder | The Author(s). | |
| dc.source | BMC Health Services Research | |
| dc.source.uri | https://bmchealthservres.biomedcentral.com/ | |
| dc.subject.other | Intervention development | |
| dc.subject.other | MRC framework | |
| dc.subject.other | Adherence | |
| dc.subject.other | Health care | |
| dc.subject.other | Self-management | |
| dc.subject.other | Behaviour modification | |
| dc.title | Using the Medical Research Council framework for development and evaluation of complex interventions in a low resource setting to develop a theory-based treatment support intervention delivered via SMS text message to improve blood pressure control | |
| dc.type | Journal Article | |
| uct.type.filetype | Text | |
| uct.type.filetype | Image |