Anaesthesia and Charcot-Marie-Tooth Disease

Journal Article

2006

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Southern African Journal of Anaesthesia and Analgesia

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MedPharm Publications

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University of Cape Town

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Abstract
Charcot-Marie-Tooth disease is named after three neurologists. Charcot and Marie first described this unusual slowly progressive hereditary motor and sensory neuropathy in France in 18861 . The muscle atrophy was characterized by weakness and wasting of the feet and leg muscles, followed by involvement of the hands. Tooth, in England, also described this peroneal type of progressive muscular atrophy with essentially the same clinical features in the same year. Tooth correctly postulated correctly that the disease was due to a neuropathy and not a myelopathy as was proposed by Charcot and Marie.
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