Prevalence and determinants of chronic kidney disease in rural and urban Cameroonians: a cross-sectional study

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dc.contributor.authorKaze, Francoisen_ZA
dc.contributor.authorMeto, Dianeen_ZA
dc.contributor.authorHalle, Marie-Patriceen_ZA
dc.contributor.authorNgogang, Jeanneen_ZA
dc.contributor.authorKengne, Andre-Pascalen_ZA
dc.date.accessioned2015-12-07T08:52:07Z
dc.date.available2015-12-07T08:52:07Z
dc.date.issued2015en_ZA
dc.description.abstractBACKGROUND: Chronic kidney disease (CKD) is a global public health problem that disproportionally affects people of African ethnicity. We assessed the prevalence and determinants of CKD and albuminuria in urban and rural adults Cameroonians. METHODS: This was a cross-sectional study of 6-month duration (February to July 2014), conducted in the health district of Dschang (Western Region of Cameroon), using a multistage cluster sampling. All adults diagnosed with albuminuria ([greater than or equal to]30mg/g) and/or decreased estimated glomerular filtration rate (eGFR) (<60ml/min/1.73m 2 ) were re-examined three months later. Logistic regression models were used to relate baseline characteristics with prevalent CKD. RESULTS: We included 439 participants with a mean age of 47+/-16.1years; with 185 (42.1%) being men and 119 (27.1%) being urban dwellers. There was a high prevalence of hypertension (25.5%), diabetes (9.8%), smoking (9.3%), alcohol consumption (59.7%), longstanding use of herbal medicine (90.9%) and street medications (87.5%), and overweight/obesity (53.3%) which were predominant in rural area. The prevalence of CKD was 13.2% overall, 14.1% in rural and 10.9% in urban participants. Equivalents figures for CKD stages G3-G4 and albuminuria were 2.5%, 1.6% and 5.0%; and 12.1%, 14.1% and 6.7% respectively. Existing hypertension and diabetes were associated with all outcomes. Elevated systolic blood pressure and the presence of hypertension and diabetes were the predictors of albuminuria and CKD while urban residence was associated with CKD stages G3-G4. CONCLUSION: The prevalence of CKD and albuminuria was high in this population, predominantly in rural area, and driven mostly by the commonest risk factors.en_ZA
dc.identifier.apacitationKaze, F., Meto, D., Halle, M., Ngogang, J., & Kengne, A. (2015). Prevalence and determinants of chronic kidney disease in rural and urban Cameroonians: a cross-sectional study. <i>BMC Nephrology</i>, http://hdl.handle.net/11427/15648en_ZA
dc.identifier.chicagocitationKaze, Francois, Diane Meto, Marie-Patrice Halle, Jeanne Ngogang, and Andre-Pascal Kengne "Prevalence and determinants of chronic kidney disease in rural and urban Cameroonians: a cross-sectional study." <i>BMC Nephrology</i> (2015) http://hdl.handle.net/11427/15648en_ZA
dc.identifier.citationKaze, F. F., Meto, D. T., Halle, M. P., Ngogang, J., & Kengne, A. P. (2015). Prevalence and determinants of chronic kidney disease in rural and urban Cameroonians: a cross-sectional study. BMC nephrology, 16(1), 117.en_ZA
dc.identifier.ris TY - Journal Article AU - Kaze, Francois AU - Meto, Diane AU - Halle, Marie-Patrice AU - Ngogang, Jeanne AU - Kengne, Andre-Pascal AB - BACKGROUND: Chronic kidney disease (CKD) is a global public health problem that disproportionally affects people of African ethnicity. We assessed the prevalence and determinants of CKD and albuminuria in urban and rural adults Cameroonians. METHODS: This was a cross-sectional study of 6-month duration (February to July 2014), conducted in the health district of Dschang (Western Region of Cameroon), using a multistage cluster sampling. All adults diagnosed with albuminuria ([greater than or equal to]30mg/g) and/or decreased estimated glomerular filtration rate (eGFR) (<60ml/min/1.73m 2 ) were re-examined three months later. Logistic regression models were used to relate baseline characteristics with prevalent CKD. RESULTS: We included 439 participants with a mean age of 47+/-16.1years; with 185 (42.1%) being men and 119 (27.1%) being urban dwellers. There was a high prevalence of hypertension (25.5%), diabetes (9.8%), smoking (9.3%), alcohol consumption (59.7%), longstanding use of herbal medicine (90.9%) and street medications (87.5%), and overweight/obesity (53.3%) which were predominant in rural area. The prevalence of CKD was 13.2% overall, 14.1% in rural and 10.9% in urban participants. Equivalents figures for CKD stages G3-G4 and albuminuria were 2.5%, 1.6% and 5.0%; and 12.1%, 14.1% and 6.7% respectively. Existing hypertension and diabetes were associated with all outcomes. Elevated systolic blood pressure and the presence of hypertension and diabetes were the predictors of albuminuria and CKD while urban residence was associated with CKD stages G3-G4. CONCLUSION: The prevalence of CKD and albuminuria was high in this population, predominantly in rural area, and driven mostly by the commonest risk factors. DA - 2015 DB - OpenUCT DO - 10.1186/s12882-015-0111-8 DP - University of Cape Town J1 - BMC Nephrology LK - https://open.uct.ac.za PB - University of Cape Town PY - 2015 T1 - Prevalence and determinants of chronic kidney disease in rural and urban Cameroonians: a cross-sectional study TI - Prevalence and determinants of chronic kidney disease in rural and urban Cameroonians: a cross-sectional study UR - http://hdl.handle.net/11427/15648 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/15648
dc.identifier.urihttp://dx.doi.org/10.1186/s12882-015-0111-8
dc.identifier.vancouvercitationKaze F, Meto D, Halle M, Ngogang J, Kengne A. Prevalence and determinants of chronic kidney disease in rural and urban Cameroonians: a cross-sectional study. BMC Nephrology. 2015; http://hdl.handle.net/11427/15648.en_ZA
dc.language.isoengen_ZA
dc.publisherBioMed Central Ltden_ZA
dc.publisher.departmentDepartment of Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Licenseen_ZA
dc.rights.holder2015 Kaze et al.en_ZA
dc.rights.urihttp://creativecommons.org/licenses/by/4.0en_ZA
dc.sourceBMC Nephrologyen_ZA
dc.source.urihttp://www.biomedcentral.com/bmcnephrol/en_ZA
dc.subject.otherChronic kidney disease (CKD)en_ZA
dc.subject.otheralbuminuriaen_ZA
dc.titlePrevalence and determinants of chronic kidney disease in rural and urban Cameroonians: a cross-sectional studyen_ZA
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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