Haemophagocytic lymphohistiocytosis following culture-proven pneumococcal infective endocarditis of the tricuspid valve
| dc.contributor.author | Hendricks, Marc | |
| dc.contributor.author | Van Eyssen, Ann Louise | |
| dc.date.accessioned | 2016-05-19T12:43:01Z | |
| dc.date.available | 2016-05-19T12:43:01Z | |
| dc.date.issued | 2012 | |
| dc.date.updated | 2016-05-19T12:36:09Z | |
| dc.description.abstract | We report a case of a 2-year-old boy presenting with persistent fever and splenomegaly who fulfilled the diagnostic criteria for haemophagocytic lymphohistiocytosis (HLH) according to the Histiocyte Society (2004). The persistence of a cardiac murmur despite multiple transfusions, and therapy which rendered him afebrile, led us to do an echocardiogram as part of surveillance for sepsis. This revealed tricuspid vegetation and a small ventricular septal defect. Blood culture and postoperative histology of the anterior leaflet of the tricuspid valve confirmed Streptococcus pneumoniae infection. The patient was successfully treated with intravenous antibiotic therapy for 6 weeks and dexamethasone for 8 weeks and remains well and in remission (from HLH) a year later with residual tricuspid regurgitation awaiting tricuspid valve replacement. | en_ZA |
| dc.identifier | http://dx.doi.org/10.7196/SAJCH.458 | |
| dc.identifier.apacitation | Hendricks, M., & Van Eyssen, A. L. (2012). Haemophagocytic lymphohistiocytosis following culture-proven pneumococcal infective endocarditis of the tricuspid valve. <i>South African Journal of Child Health</i>, http://hdl.handle.net/11427/19721 | en_ZA |
| dc.identifier.chicagocitation | Hendricks, Marc, and Ann Louise Van Eyssen "Haemophagocytic lymphohistiocytosis following culture-proven pneumococcal infective endocarditis of the tricuspid valve." <i>South African Journal of Child Health</i> (2012) http://hdl.handle.net/11427/19721 | en_ZA |
| dc.identifier.citation | van Eyssen, A. L., & Hendricks, M. (2012). Haemophagocytic lymphohistiocytosis following culture-proven pneumococcal infective endocarditis of the tricuspid valve. South African Journal of Child Health, 6(3), 85-87. | en_ZA |
| dc.identifier.issn | 1999-7671 | en_ZA |
| dc.identifier.ris | TY - Journal Article AU - Hendricks, Marc AU - Van Eyssen, Ann Louise AB - We report a case of a 2-year-old boy presenting with persistent fever and splenomegaly who fulfilled the diagnostic criteria for haemophagocytic lymphohistiocytosis (HLH) according to the Histiocyte Society (2004). The persistence of a cardiac murmur despite multiple transfusions, and therapy which rendered him afebrile, led us to do an echocardiogram as part of surveillance for sepsis. This revealed tricuspid vegetation and a small ventricular septal defect. Blood culture and postoperative histology of the anterior leaflet of the tricuspid valve confirmed Streptococcus pneumoniae infection. The patient was successfully treated with intravenous antibiotic therapy for 6 weeks and dexamethasone for 8 weeks and remains well and in remission (from HLH) a year later with residual tricuspid regurgitation awaiting tricuspid valve replacement. DA - 2012 DB - OpenUCT DP - University of Cape Town J1 - South African Journal of Child Health LK - https://open.uct.ac.za PB - University of Cape Town PY - 2012 SM - 1999-7671 T1 - Haemophagocytic lymphohistiocytosis following culture-proven pneumococcal infective endocarditis of the tricuspid valve TI - Haemophagocytic lymphohistiocytosis following culture-proven pneumococcal infective endocarditis of the tricuspid valve UR - http://hdl.handle.net/11427/19721 ER - | en_ZA |
| dc.identifier.uri | http://hdl.handle.net/11427/19721 | |
| dc.identifier.uri | http://sajch.org.za/index.php/SAJCH/article/view/458 | |
| dc.identifier.vancouvercitation | Hendricks M, Van Eyssen AL. Haemophagocytic lymphohistiocytosis following culture-proven pneumococcal infective endocarditis of the tricuspid valve. South African Journal of Child Health. 2012; http://hdl.handle.net/11427/19721. | en_ZA |
| dc.language | eng | en_ZA |
| dc.publisher | Health and Medical Publishing Group | en_ZA |
| dc.publisher.department | Department of Paediatrics and Child Health | en_ZA |
| dc.publisher.faculty | Faculty of Health Sciences | en_ZA |
| dc.publisher.institution | University of Cape Town | |
| dc.rights | Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | en_ZA |
| dc.source | South African Journal of Child Health | en_ZA |
| dc.source.uri | http://www.sajch.org.za/index.php/SAJCH | |
| dc.subject.other | haemophagocytic lymphohistiocytosis | |
| dc.subject.other | pneumococcal endocarditis | |
| dc.title | Haemophagocytic lymphohistiocytosis following culture-proven pneumococcal infective endocarditis of the tricuspid valve | en_ZA |
| dc.type | Journal Article | en_ZA |
| uct.type.filetype | Text | |
| uct.type.filetype | Image | |
| uct.type.publication | Research | en_ZA |
| uct.type.resource | Article | en_ZA |