Reference intervals for the echocardiographic measurements of the right heart in children and adolescents: a systematic review

Simple item page
dc.contributor.authorLemmer (Hunsinger), Carolinaen_ZA
dc.contributor.authorEngel, Mark Een_ZA
dc.contributor.authorStanfliet, Johnen_ZA
dc.contributor.authorMayosi, Bonganien_ZA
dc.date.accessioned2015-11-27T09:33:42Z
dc.date.available2015-11-27T09:33:42Z
dc.date.issued2014en_ZA
dc.description.abstractBACKGROUND: Transthoracic echocardiography is the primary imaging modality for the diagnosis of right ventricular (RV) involvement in congenital and acquired heart diseases. There is increasing recognition of the contribution of RV dysfunction in heart diseases affecting children and adolescents, but there is insufficient information on reference intervals for the echocardiographic measurements of the right heart in children and adolescents that represent all the continental populations of the world.OBJECTIVE:The aim of this systematic review was to collate, from published studies, normative data for echocardiographic evaluation of the right heart in children and adolescents, and to identify gaps in knowledge in this field especially with respect to sub-Saharan Africans. METHODS: We performed a systematic literature search to identify studies of reference intervals for right heart measurements as determined by transthoracic echocardiography in healthy children and adolescents of school-going age. Articles were retrieved from electronic databases with a combination of search terms from the earliest date available until May 2013. RESULTS: Reference data were available for a broad range of variables. Fifty one studies out of 3096 publications were included. The sample sizes of the reference populations ranged from 13 to 2036 with ages varying from 5 to 21 years. We identified areas lacking sufficient reference data. These included reference data for determining right atrial size, tricuspid valve area, RV dimensions and areas, the RV % fractional area change, pulmonary artery pressure gradients and the right-sided haemodynamics, including the inferior vena cava dimensions and collapsibility. There were no data for sub-Saharan African children and adolescents. CONCLUSION: Reliable reference data are lacking for important echocardiographic measurements of the RV in children and adolescents, especially for sub-Saharan Africans.en_ZA
dc.identifier.apacitation, Engel, M. E., Stanfliet, J., & Mayosi, B. (2014). Reference intervals for the echocardiographic measurements of the right heart in children and adolescents: a systematic review. <i>Cardiovascular Ultrasound</i>, http://hdl.handle.net/11427/15402en_ZA
dc.identifier.chicagocitation, Mark E Engel, John Stanfliet, and Bongani Mayosi "Reference intervals for the echocardiographic measurements of the right heart in children and adolescents: a systematic review." <i>Cardiovascular Ultrasound</i> (2014) http://hdl.handle.net/11427/15402en_ZA
dc.identifier.citationLemmer, C. E., Engel, M. E., Stanfliet, J. C., & Mayosi, B. M. (2014). Reference intervals for the echocardiographic measurements of the right heart in children and adolescents: a systematic review. Cardiovascular ultrasound, 12(1), 3.en_ZA
dc.identifier.ris TY - Journal Article AU - Lemmer (Hunsinger), Carolina AU - Engel, Mark E AU - Stanfliet, John AU - Mayosi, Bongani AB - BACKGROUND: Transthoracic echocardiography is the primary imaging modality for the diagnosis of right ventricular (RV) involvement in congenital and acquired heart diseases. There is increasing recognition of the contribution of RV dysfunction in heart diseases affecting children and adolescents, but there is insufficient information on reference intervals for the echocardiographic measurements of the right heart in children and adolescents that represent all the continental populations of the world.OBJECTIVE:The aim of this systematic review was to collate, from published studies, normative data for echocardiographic evaluation of the right heart in children and adolescents, and to identify gaps in knowledge in this field especially with respect to sub-Saharan Africans. METHODS: We performed a systematic literature search to identify studies of reference intervals for right heart measurements as determined by transthoracic echocardiography in healthy children and adolescents of school-going age. Articles were retrieved from electronic databases with a combination of search terms from the earliest date available until May 2013. RESULTS: Reference data were available for a broad range of variables. Fifty one studies out of 3096 publications were included. The sample sizes of the reference populations ranged from 13 to 2036 with ages varying from 5 to 21 years. We identified areas lacking sufficient reference data. These included reference data for determining right atrial size, tricuspid valve area, RV dimensions and areas, the RV % fractional area change, pulmonary artery pressure gradients and the right-sided haemodynamics, including the inferior vena cava dimensions and collapsibility. There were no data for sub-Saharan African children and adolescents. CONCLUSION: Reliable reference data are lacking for important echocardiographic measurements of the RV in children and adolescents, especially for sub-Saharan Africans. DA - 2014 DB - OpenUCT DO - 10.1186/1476-7120-12-3 DP - University of Cape Town J1 - Cardiovascular Ultrasound LK - https://open.uct.ac.za PB - University of Cape Town PY - 2014 T1 - Reference intervals for the echocardiographic measurements of the right heart in children and adolescents: a systematic review TI - Reference intervals for the echocardiographic measurements of the right heart in children and adolescents: a systematic review UR - http://hdl.handle.net/11427/15402 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/15402
dc.identifier.urihttp://dx.doi.org/10.1186/1476-7120-12-3
dc.identifier.vancouvercitation, Engel ME, Stanfliet J, Mayosi B. Reference intervals for the echocardiographic measurements of the right heart in children and adolescents: a systematic review. Cardiovascular Ultrasound. 2014; http://hdl.handle.net/11427/15402.en_ZA
dc.language.isoengen_ZA
dc.publisherBioMed Central Ltden_ZA
dc.publisher.departmentDepartment of Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Licenseen_ZA
dc.rights.holder2014 Lemmer (Hunsinger) et al.; licensee BioMed Central Ltd.en_ZA
dc.rights.urihttp://creativecommons.org/licenses/by/2.0en_ZA
dc.sourceCardiovascular Ultrasounden_ZA
dc.source.urihttp://www.cardiovascularultrasound.com/en_ZA
dc.subject.otherEchocardiographyen_ZA
dc.subject.otherReference rangesen_ZA
dc.subject.otherNormal valuesen_ZA
dc.subject.otherRight ventricleen_ZA
dc.subject.otherRight atriumen_ZA
dc.subject.otherTricuspiden_ZA
dc.subject.otherPulmonaryen_ZA
dc.subject.otherVena cavaen_ZA
dc.subject.otherPaediatricen_ZA
dc.titleReference intervals for the echocardiographic measurements of the right heart in children and adolescents: a systematic reviewen_ZA
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Lemmer_Reference_intervals_2014.pdf
Size:
597.65 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Journal Articles