Anaesthetic method and short-term outcomes of preterm infants delivered by caesarean section in a tertiary hospital in South Africa

dc.contributor.advisorHorn, Alan
dc.contributor.advisorTooke Lloyd
dc.contributor.authorStander, Raphaella
dc.date.accessioned2022-01-19T23:02:58Z
dc.date.available2022-01-19T23:02:58Z
dc.date.issued2021
dc.date.updated2022-01-19T23:01:57Z
dc.description.abstractBackground. There are inconsistent published data describing the influence of anaesthetic type during caesarean section (CS), on outcomes of preterm neonates. Objectives. To describe indications and type of anaesthesia in preterm neonates and to describe short-term outcomes, comparing spinal anaesthesia (SA) to general anaesthesia (GA). Methods. Data were collected retrospectively on preterm babies born at 28 – 35 weeks' gestation by CS, between 1 January and 30 Sep 2014 at Groote Schuur Hospital, Cape Town, South Africa. Babies with missing data were excluded. The largest group of babies with similar indications for delivery were identified from the theatre register. Baseline characteristics and short-term outcomes for this group were extracted from an existing prospective data base, and compared between those delivered under SA and GA. Results. Data were available for 226 deliveries, having excluded 23 with incomplete data. Most babies (75%) were delivered under SA. The most common indication for CS was ‘cardiotocograph abnormalities,' in 139 deliveries. Within this group, SA was more frequent (81.7% vs. 12.9%) while GA was associated with lower Apgar scores (p < 0.001) and more intubation at birth (p = 0.004). There was no difference in mortality when comparing SA with GA. Conclusion. Our data suggest a sedative effect of maternal GA on preterm babies delivered by CS, and the need for staff with advanced resuscitation skills. This study provides novel baseline data in our setting, but these data need to be validated in a prospective study.
dc.identifier.apacitationStander, R. (2021). <i>Anaesthetic method and short-term outcomes of preterm infants delivered by caesarean section in a tertiary hospital in South Africa</i>. (). ,Faculty of Health Sciences ,Department of Paediatrics and Child Health. Retrieved from http://hdl.handle.net/11427/35520en_ZA
dc.identifier.chicagocitationStander, Raphaella. <i>"Anaesthetic method and short-term outcomes of preterm infants delivered by caesarean section in a tertiary hospital in South Africa."</i> ., ,Faculty of Health Sciences ,Department of Paediatrics and Child Health, 2021. http://hdl.handle.net/11427/35520en_ZA
dc.identifier.citationStander, R. 2021. Anaesthetic method and short-term outcomes of preterm infants delivered by caesarean section in a tertiary hospital in South Africa. . ,Faculty of Health Sciences ,Department of Paediatrics and Child Health. http://hdl.handle.net/11427/35520en_ZA
dc.identifier.ris TY - Master Thesis AU - Stander, Raphaella AB - Background. There are inconsistent published data describing the influence of anaesthetic type during caesarean section (CS), on outcomes of preterm neonates. Objectives. To describe indications and type of anaesthesia in preterm neonates and to describe short-term outcomes, comparing spinal anaesthesia (SA) to general anaesthesia (GA). Methods. Data were collected retrospectively on preterm babies born at 28 – 35 weeks' gestation by CS, between 1 January and 30 Sep 2014 at Groote Schuur Hospital, Cape Town, South Africa. Babies with missing data were excluded. The largest group of babies with similar indications for delivery were identified from the theatre register. Baseline characteristics and short-term outcomes for this group were extracted from an existing prospective data base, and compared between those delivered under SA and GA. Results. Data were available for 226 deliveries, having excluded 23 with incomplete data. Most babies (75%) were delivered under SA. The most common indication for CS was ‘cardiotocograph abnormalities,' in 139 deliveries. Within this group, SA was more frequent (81.7% vs. 12.9%) while GA was associated with lower Apgar scores (p < 0.001) and more intubation at birth (p = 0.004). There was no difference in mortality when comparing SA with GA. Conclusion. Our data suggest a sedative effect of maternal GA on preterm babies delivered by CS, and the need for staff with advanced resuscitation skills. This study provides novel baseline data in our setting, but these data need to be validated in a prospective study. DA - 2021 DB - OpenUCT DP - University of Cape Town KW - Paediatrics and Child Health LK - https://open.uct.ac.za PY - 2021 T1 - Anaesthetic method and short-term outcomes of preterm infants delivered by caesarean section in a tertiary hospital in South Africa TI - Anaesthetic method and short-term outcomes of preterm infants delivered by caesarean section in a tertiary hospital in South Africa UR - http://hdl.handle.net/11427/35520 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/35520
dc.identifier.vancouvercitationStander R. Anaesthetic method and short-term outcomes of preterm infants delivered by caesarean section in a tertiary hospital in South Africa. []. ,Faculty of Health Sciences ,Department of Paediatrics and Child Health, 2021 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/35520en_ZA
dc.language.rfc3066eng
dc.publisher.departmentDepartment of Paediatrics and Child Health
dc.publisher.facultyFaculty of Health Sciences
dc.subjectPaediatrics and Child Health
dc.titleAnaesthetic method and short-term outcomes of preterm infants delivered by caesarean section in a tertiary hospital in South Africa
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationlevelMMed
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