Modelling of batch and fed-batch ethanol fermentation

Simple item page
dc.contributor.advisorHansford, Geoffrey Spearingen_ZA
dc.contributor.authorGlyn, Julian E Hen_ZA
dc.date.accessioned2016-09-20T12:31:41Z
dc.date.available2016-09-20T12:31:41Z
dc.date.issued1989en_ZA
dc.description.abstractTwo series of batch and fed-batch fermentations were carried out using S.cerevisiae in a semi-defined medium containing 200 gl-1 glucose as limiting substrate. Growth rates were calculated and the data used to test the applicability of eight empirical kinetic models. The form proposed by Levenspiel, combining the concept of a limiting ethanol concentration with a power-law form, gave the best results with these data. Glucose concentration was found to have a far smaller, though not negligible, effect on growth rate under these conditions. It was also observed that in fed-batch fermentations the total substrate uptake rate of the broth became constant soon after commencement of feeding, without cessation of growth. It is suggested that ethanol inhibits the synthesis of a rate-controlling enzyme in the glycolyti·c chain, but no previous work could be found to support or refute this explanation. A quasi-mechanistic model of growth under the condition of constant substrate consumption rate is formulated and discussed.en_ZA
dc.identifier.apacitationGlyn, J. E. H. (1989). <i>Modelling of batch and fed-batch ethanol fermentation</i>. (Thesis). University of Cape Town ,Faculty of Engineering & the Built Environment ,Department of Chemical Engineering. Retrieved from http://hdl.handle.net/11427/21832en_ZA
dc.identifier.chicagocitationGlyn, Julian E H. <i>"Modelling of batch and fed-batch ethanol fermentation."</i> Thesis., University of Cape Town ,Faculty of Engineering & the Built Environment ,Department of Chemical Engineering, 1989. http://hdl.handle.net/11427/21832en_ZA
dc.identifier.citationGlyn, J. 1989. Modelling of batch and fed-batch ethanol fermentation. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Glyn, Julian E H AB - Two series of batch and fed-batch fermentations were carried out using S.cerevisiae in a semi-defined medium containing 200 gl-1 glucose as limiting substrate. Growth rates were calculated and the data used to test the applicability of eight empirical kinetic models. The form proposed by Levenspiel, combining the concept of a limiting ethanol concentration with a power-law form, gave the best results with these data. Glucose concentration was found to have a far smaller, though not negligible, effect on growth rate under these conditions. It was also observed that in fed-batch fermentations the total substrate uptake rate of the broth became constant soon after commencement of feeding, without cessation of growth. It is suggested that ethanol inhibits the synthesis of a rate-controlling enzyme in the glycolyti·c chain, but no previous work could be found to support or refute this explanation. A quasi-mechanistic model of growth under the condition of constant substrate consumption rate is formulated and discussed. DA - 1989 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 1989 T1 - Modelling of batch and fed-batch ethanol fermentation TI - Modelling of batch and fed-batch ethanol fermentation UR - http://hdl.handle.net/11427/21832 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/21832
dc.identifier.vancouvercitationGlyn JEH. Modelling of batch and fed-batch ethanol fermentation. [Thesis]. University of Cape Town ,Faculty of Engineering & the Built Environment ,Department of Chemical Engineering, 1989 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/21832en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Chemical Engineeringen_ZA
dc.publisher.facultyFaculty of Engineering and the Built Environment
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherFermentationen_ZA
dc.subject.otherAlcoholen_ZA
dc.subject.otherChemical Engineeringen_ZA
dc.titleModelling of batch and fed-batch ethanol fermentationen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMSc (Eng)en_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
thesis_ebe_1989_glyn_julian_e_h.pdf
Size:
1.75 MB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Masters