Inflammation in the male genital tract: implications for HIV acquisition and transmission

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dc.contributor.authorOlivier, Abraham Jacobusen_ZA
dc.contributor.authorRoberts, Len_ZA
dc.contributor.authorCoetzee, Den_ZA
dc.contributor.authorWilliamson, Aen_ZA
dc.contributor.authorPassmore, JSen_ZA
dc.contributor.authorBurgers, WAen_ZA
dc.date.accessioned2015-11-18T04:02:45Z
dc.date.available2015-11-18T04:02:45Z
dc.date.issued2012en_ZA
dc.description.abstractElevated plasma levels of pro-inflammatory mediators such as TNFα, IL-1β, IL-6 and IL-8, MIP-1α, MIP-1β and RANTES have been demonstrated in HIV-infected individuals and HIV induces higher levels of pro-inflammatory cytokines in the female genital tract. We characterized levels of inflammation in semen, to gain an understanding of factors influencing transmission and acquisition in the male genital tract. Our hypothesis was that infected men would exhibit higher levels of inflammation in semen than uninfected men.en_ZA
dc.identifier.apacitationOlivier, A. J., Roberts, L., Coetzee, D., Williamson, A., Passmore, J., & Burgers, W. (2012). Inflammation in the male genital tract: implications for HIV acquisition and transmission. <i>Retrovirology</i>, http://hdl.handle.net/11427/15102en_ZA
dc.identifier.chicagocitationOlivier, Abraham Jacobus, L Roberts, D Coetzee, A Williamson, JS Passmore, and WA Burgers "Inflammation in the male genital tract: implications for HIV acquisition and transmission." <i>Retrovirology</i> (2012) http://hdl.handle.net/11427/15102en_ZA
dc.identifier.citationOlivier, A. J., Roberts, L., Coetzee, D., Williamson, A., Passmore, J. S., & Burgers, W. A. (2012). Inflammation in the male genital tract: implications for HIV acquisition and transmission. Retrovirology, 9(Suppl 2), O23.en_ZA
dc.identifier.ris TY - Journal Article AU - Olivier, Abraham Jacobus AU - Roberts, L AU - Coetzee, D AU - Williamson, A AU - Passmore, JS AU - Burgers, WA AB - Elevated plasma levels of pro-inflammatory mediators such as TNFα, IL-1β, IL-6 and IL-8, MIP-1α, MIP-1β and RANTES have been demonstrated in HIV-infected individuals and HIV induces higher levels of pro-inflammatory cytokines in the female genital tract. We characterized levels of inflammation in semen, to gain an understanding of factors influencing transmission and acquisition in the male genital tract. Our hypothesis was that infected men would exhibit higher levels of inflammation in semen than uninfected men. DA - 2012 DB - OpenUCT DO - 10.1186/1742-4690-9-S2-O23 DP - University of Cape Town J1 - Retrovirology LK - https://open.uct.ac.za PB - University of Cape Town PY - 2012 T1 - Inflammation in the male genital tract: implications for HIV acquisition and transmission TI - Inflammation in the male genital tract: implications for HIV acquisition and transmission UR - http://hdl.handle.net/11427/15102 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/15102
dc.identifier.urihttp://dx.doi.org/10.1186/1742-4690-9-S2-O23
dc.identifier.vancouvercitationOlivier AJ, Roberts L, Coetzee D, Williamson A, Passmore J, Burgers W. Inflammation in the male genital tract: implications for HIV acquisition and transmission. Retrovirology. 2012; http://hdl.handle.net/11427/15102.en_ZA
dc.language.isoengen_ZA
dc.publisherBioMed Central Ltden_ZA
dc.publisher.departmentDepartment of Public Health and Family Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Licenseen_ZA
dc.rights.holder2012 Olivier et al; licensee BioMed Central Ltd.en_ZA
dc.rights.urihttp://creativecommons.org/licenses/by/2.0en_ZA
dc.sourceRetrovirologyen_ZA
dc.source.urihttp://www.retrovirology.com/en_ZA
dc.subject.otherHIV acquisitionen_ZA
dc.subject.otherHIV transmissionen_ZA
dc.subject.othermale genital tracten_ZA
dc.titleInflammation in the male genital tract: implications for HIV acquisition and transmissionen_ZA
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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