Prevalence and correlates of depressive symptoms in adult patients with pulmonary tuberculosis in the Southwest Region of Cameroon

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dc.contributor.authorKehbila, Jules
dc.contributor.authorEkabe, Cyril Jabea
dc.contributor.authorAminde, Leopold Ndemnge
dc.contributor.authorNoubiap, Jean Jacques N
dc.contributor.authorFon, Peter Nde
dc.contributor.authorMonekosso, Gottlieb Lobe
dc.date.accessioned2021-10-08T07:04:15Z
dc.date.available2021-10-08T07:04:15Z
dc.date.issued2016
dc.description.abstractAbstract Background Tuberculosis (TB) remains a global health challenge and depression is a significant contributor to the global burden of disease. Current evidence suggests that there is an association between depressive symptoms and TB, lower adherence to treatment, and increased morbidity and mortality. However, there is paucity of data regarding these associations in Cameroon. This study aimed to determine the prevalence and correlates of depression in adult patients with pulmonary TB (PTB) in the Southwest Region of Cameroon. Methods A hospital-based cross-sectional study involving 265 patients with PTB was conducted from 2 nd January to 31 st March 2015 in the Limbe Regional Hospital and the Kumba District Hospital. Depression was diagnosed using the standard nine-item Patient Health Questionnaire, and classified as none, mild or moderate. Logistic regressions were used to investigate correlates of depression in these patients. Results Of the 265 patients (mean age 36.9 ± 10 years) studied, 136 (51.3 %) were female. The prevalence of depression was 61.1 % (95 % CI: 55.1–66.8), with a significant proportion (36.6 %) having mild depression. Multivariable logistic regression analysis showed that being female (aOR = 3.0, 95 % CI (1.7–5.5), P < 0.001), having a family history of mental illness (aOR = 2.5, 95 % CI: 1.3–5.4, P > 0.05), being on retreatment for TB (aOR = 11.2, 95 % CI: 5.2–31.1, P < 0.001), having discontinued treatment (aOR = 8.2, 95 % CI: 1.1–23.3, P < 0.05) and having a HIV/TB co-infection (aOR = 2.5, 95 % CI: 1.2–6.5, P < 0.001) were factors associated with having a higher chance of being depressed. Conclusion Our study suggests that there is a high prevalence of depression among PTB patients, with more than one in two patients affected. Multidisciplinary care for TB patients involving mental health practitioners is highly encouraged, especially for high-risk groups.
dc.identifier.apacitationKehbila, J., Ekabe, C. J., Aminde, L. N., Noubiap, J. J. N., Fon, P. N., & Monekosso, G. L. (2016). Prevalence and correlates of depressive symptoms in adult patients with pulmonary tuberculosis in the Southwest Region of Cameroon. <i>Infectious Diseases of Poverty</i>, 5(1), 174 - 177. http://hdl.handle.net/11427/34463en_ZA
dc.identifier.chicagocitationKehbila, Jules, Cyril Jabea Ekabe, Leopold Ndemnge Aminde, Jean Jacques N Noubiap, Peter Nde Fon, and Gottlieb Lobe Monekosso "Prevalence and correlates of depressive symptoms in adult patients with pulmonary tuberculosis in the Southwest Region of Cameroon." <i>Infectious Diseases of Poverty</i> 5, 1. (2016): 174 - 177. http://hdl.handle.net/11427/34463en_ZA
dc.identifier.citationKehbila, J., Ekabe, C.J., Aminde, L.N., Noubiap, J.J.N., Fon, P.N. & Monekosso, G.L. 2016. Prevalence and correlates of depressive symptoms in adult patients with pulmonary tuberculosis in the Southwest Region of Cameroon. <i>Infectious Diseases of Poverty.</i> 5(1):174 - 177. http://hdl.handle.net/11427/34463en_ZA
dc.identifier.issn2049-9957
dc.identifier.issn2095-5162
dc.identifier.ris TY - Journal Article AU - Kehbila, Jules AU - Ekabe, Cyril Jabea AU - Aminde, Leopold Ndemnge AU - Noubiap, Jean Jacques N AU - Fon, Peter Nde AU - Monekosso, Gottlieb Lobe AB - Abstract Background Tuberculosis (TB) remains a global health challenge and depression is a significant contributor to the global burden of disease. Current evidence suggests that there is an association between depressive symptoms and TB, lower adherence to treatment, and increased morbidity and mortality. However, there is paucity of data regarding these associations in Cameroon. This study aimed to determine the prevalence and correlates of depression in adult patients with pulmonary TB (PTB) in the Southwest Region of Cameroon. Methods A hospital-based cross-sectional study involving 265 patients with PTB was conducted from 2 nd January to 31 st March 2015 in the Limbe Regional Hospital and the Kumba District Hospital. Depression was diagnosed using the standard nine-item Patient Health Questionnaire, and classified as none, mild or moderate. Logistic regressions were used to investigate correlates of depression in these patients. Results Of the 265 patients (mean age 36.9 ± 10 years) studied, 136 (51.3 %) were female. The prevalence of depression was 61.1 % (95 % CI: 55.1–66.8), with a significant proportion (36.6 %) having mild depression. Multivariable logistic regression analysis showed that being female (aOR = 3.0, 95 % CI (1.7–5.5), P < 0.001), having a family history of mental illness (aOR = 2.5, 95 % CI: 1.3–5.4, P > 0.05), being on retreatment for TB (aOR = 11.2, 95 % CI: 5.2–31.1, P < 0.001), having discontinued treatment (aOR = 8.2, 95 % CI: 1.1–23.3, P < 0.05) and having a HIV/TB co-infection (aOR = 2.5, 95 % CI: 1.2–6.5, P < 0.001) were factors associated with having a higher chance of being depressed. Conclusion Our study suggests that there is a high prevalence of depression among PTB patients, with more than one in two patients affected. Multidisciplinary care for TB patients involving mental health practitioners is highly encouraged, especially for high-risk groups. DA - 2016 DB - OpenUCT DP - University of Cape Town IS - 1 J1 - Infectious Diseases of Poverty LK - https://open.uct.ac.za PY - 2016 SM - 2049-9957 SM - 2095-5162 T1 - Prevalence and correlates of depressive symptoms in adult patients with pulmonary tuberculosis in the Southwest Region of Cameroon TI - Prevalence and correlates of depressive symptoms in adult patients with pulmonary tuberculosis in the Southwest Region of Cameroon UR - http://hdl.handle.net/11427/34463 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/34463
dc.identifier.vancouvercitationKehbila J, Ekabe CJ, Aminde LN, Noubiap JJN, Fon PN, Monekosso GL. Prevalence and correlates of depressive symptoms in adult patients with pulmonary tuberculosis in the Southwest Region of Cameroon. Infectious Diseases of Poverty. 2016;5(1):174 - 177. http://hdl.handle.net/11427/34463.en_ZA
dc.language.isoeng
dc.publisher.departmentDepartment of Medicine
dc.publisher.facultyFaculty of Health Sciences
dc.sourceInfectious Diseases of Poverty
dc.source.journalissue1
dc.source.journalvolume5
dc.source.pagination174 - 177
dc.source.urihttps://dx.doi.org/10.1186/s40249-016-0145-6
dc.subject.otherCameroon
dc.subject.otherCorrelates
dc.subject.otherDepression
dc.subject.otherPrevalence
dc.subject.otherPulmonary tuberculosis
dc.subject.otherAdult
dc.subject.otherCameroon
dc.subject.otherComorbidity
dc.subject.otherCross-Sectional Studies
dc.subject.otherDepression
dc.subject.otherFemale
dc.subject.otherHumans
dc.subject.otherMale
dc.subject.otherMiddle Aged
dc.subject.otherPrevalence
dc.subject.otherTuberculosis, Pulmonary
dc.subject.otherYoung Adult
dc.titlePrevalence and correlates of depressive symptoms in adult patients with pulmonary tuberculosis in the Southwest Region of Cameroon
dc.typeJournal Article
uct.type.publicationResearch
uct.type.resourceJournal Article
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