Effectiveness of mobile text reminder in improving adherence to medication, physical exercise, and quality of life in patients living with HIV: a systematic review

dc.contributor.authorIbeneme, Sam C.
dc.contributor.authorNdukwu, Sandra C.
dc.contributor.authorMyezwa, Hellen
dc.contributor.authorIrem, Franklin O.
dc.contributor.authorEzenwankwo, Fortune E.
dc.contributor.authorAjidahun, Adedayo T.
dc.contributor.authorEzuma, Amarachi D.
dc.contributor.authorNnamani, Amaka
dc.contributor.authorOnodugo, Obinna
dc.contributor.authorFortwengel, Gerhard
dc.contributor.authorUwakwe, Victor C.
dc.date.accessioned2021-10-06T12:47:11Z
dc.date.available2021-10-06T12:47:11Z
dc.date.issued2021-08-23
dc.date.updated2021-08-29T03:10:30Z
dc.description.abstractBackground Mobile text reminder (SMS) system is considered a viable strategy for targeting/facilitating healthy behavioural change including adherence to prescribed physical exercises (PE) and medication (antiretroviral therapy-ART) which should improve the quality of life (Qol) in people living with HIV/AIDS(PLWHA). Thus, the literature was appraised for evidence of SMS effectiveness in improving ART and PE adherence behaviours and QoL in PLWHA. Methods Eight databases–AMED, CINAHL, Cochrane Library, EMBASE, EMCARE, Ovid MEDLINE, PsycINFO, and PubMed-were searched up to December 2020, using the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) protocol.This review included only randomised control trials (RCTs) investigating the effectiveness of SMS in improving QoL or PE or ART adherence behaviour or a combination of these variables in PLWHA >18 years. Two independent reviewers determined the eligibility of the studies. Data were extracted and the quality of the study was assessed with the Physiotherapy Evidence Database (PEDro) tool. The primary outcomes were ART and PE adherence behaviours while the secondary outcome was QoL. Result A pooled estimate of effect was not calculated due to the heterogeneity of methods and outcome measures. Therefore, a narrative synthesis of ten studies that met the inclusion criteria (n = 1621 participants at study completion) comprising males/females, aged ≥ 18 years, was done. There was a significant improvement in ART adherence behaviour except in three underpowered studies. Only the SMS interventions that were developed using the Starks 3-steps Adherence model was associated with positive outcome. The only study that evaluated QoL was underpowered and reported no significant change while there were no RCTs on PE. Conclusion Effects of SMS intervention trends towards a significant improvement in ART adherence behaviour in PLWHA. It is plausible that SMS reminders developed using the broader framework of the interpersonal health behaviour theory(ies) may have positive outcome. Nevertheless, the observed heterogeneity in the methods/outcome measures warrants a cautious interpretation of the findings. There is a lack/paucity of RCTs and therefore no evidence in support of the effectiveness of SMS intervention in improving PE adherence and QoL. Registration number NPLASY202060016.en_US
dc.identifier.apacitationIbeneme, Sam C., Ndukwu, Sandra C., Myezwa, H., Irem, Franklin O., Ezenwankwo, Fortune E., Ajidahun, Adedayo T., ... Uwakwe, Victor C. (2021). Effectiveness of mobile text reminder in improving adherence to medication, physical exercise, and quality of life in patients living with HIV: a systematic review. <i>BMC Infectious Diseases</i>, 21(Article number: 859), http://hdl.handle.net/11427/34101en_ZA
dc.identifier.chicagocitationIbeneme, Sam C., Sandra C. Ndukwu, Hellen Myezwa, Franklin O. Irem, Fortune E. Ezenwankwo, Adedayo T. Ajidahun, Amarachi D. Ezuma, et al "Effectiveness of mobile text reminder in improving adherence to medication, physical exercise, and quality of life in patients living with HIV: a systematic review." <i>BMC Infectious Diseases</i> 21, Article number: 859. (2021) http://hdl.handle.net/11427/34101en_ZA
dc.identifier.citationIbeneme, Sam C., Ndukwu, Sandra C., Myezwa, H., Irem, Franklin O., Ezenwankwo, Fortune E., Ajidahun, Adedayo T., Ezuma, Amarachi D. & Nnamani, A. et al. 2021. Effectiveness of mobile text reminder in improving adherence to medication, physical exercise, and quality of life in patients living with HIV: a systematic review. <i>BMC Infectious Diseases.</i> 21(Article number: 859) http://hdl.handle.net/11427/34101en_ZA
dc.identifier.ris TY - Journal Article AU - Ibeneme, Sam C. AU - Ndukwu, Sandra C. AU - Myezwa, Hellen AU - Irem, Franklin O. AU - Ezenwankwo, Fortune E. AU - Ajidahun, Adedayo T. AU - Ezuma, Amarachi D. AU - Nnamani, Amaka AU - Onodugo, Obinna AU - Fortwengel, Gerhard AU - Uwakwe, Victor C. AB - Background Mobile text reminder (SMS) system is considered a viable strategy for targeting/facilitating healthy behavioural change including adherence to prescribed physical exercises (PE) and medication (antiretroviral therapy-ART) which should improve the quality of life (Qol) in people living with HIV/AIDS(PLWHA). Thus, the literature was appraised for evidence of SMS effectiveness in improving ART and PE adherence behaviours and QoL in PLWHA. Methods Eight databases–AMED, CINAHL, Cochrane Library, EMBASE, EMCARE, Ovid MEDLINE, PsycINFO, and PubMed-were searched up to December 2020, using the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) protocol.This review included only randomised control trials (RCTs) investigating the effectiveness of SMS in improving QoL or PE or ART adherence behaviour or a combination of these variables in PLWHA >18 years. Two independent reviewers determined the eligibility of the studies. Data were extracted and the quality of the study was assessed with the Physiotherapy Evidence Database (PEDro) tool. The primary outcomes were ART and PE adherence behaviours while the secondary outcome was QoL. Result A pooled estimate of effect was not calculated due to the heterogeneity of methods and outcome measures. Therefore, a narrative synthesis of ten studies that met the inclusion criteria (n = 1621 participants at study completion) comprising males/females, aged ≥ 18 years, was done. There was a significant improvement in ART adherence behaviour except in three underpowered studies. Only the SMS interventions that were developed using the Starks 3-steps Adherence model was associated with positive outcome. The only study that evaluated QoL was underpowered and reported no significant change while there were no RCTs on PE. Conclusion Effects of SMS intervention trends towards a significant improvement in ART adherence behaviour in PLWHA. It is plausible that SMS reminders developed using the broader framework of the interpersonal health behaviour theory(ies) may have positive outcome. Nevertheless, the observed heterogeneity in the methods/outcome measures warrants a cautious interpretation of the findings. There is a lack/paucity of RCTs and therefore no evidence in support of the effectiveness of SMS intervention in improving PE adherence and QoL. Registration number NPLASY202060016. DA - 2021-08-23 DB - OpenUCT DP - University of Cape Town IS - Article number: 859 J1 - BMC Infectious Diseases KW - HIV KW - Antiretroviral therapy KW - Cell phone KW - Text-message KW - Medication adherence KW - Physical exercise adherence KW - Quality of life LK - https://open.uct.ac.za PY - 2021 T1 - Effectiveness of mobile text reminder in improving adherence to medication, physical exercise, and quality of life in patients living with HIV: a systematic review TI - Effectiveness of mobile text reminder in improving adherence to medication, physical exercise, and quality of life in patients living with HIV: a systematic review UR - http://hdl.handle.net/11427/34101 ER - en_ZA
dc.identifier.urihttps://doi.org/10.1186/s12879-021-06563-0
dc.identifier.urihttp://hdl.handle.net/11427/34101
dc.identifier.vancouvercitationIbeneme Sam C, Ndukwu Sandra C, Myezwa H, Irem Franklin O, Ezenwankwo Fortune E, Ajidahun Adedayo T, et al. Effectiveness of mobile text reminder in improving adherence to medication, physical exercise, and quality of life in patients living with HIV: a systematic review. BMC Infectious Diseases. 2021;21(Article number: 859) http://hdl.handle.net/11427/34101.en_ZA
dc.language.isoenen_US
dc.language.rfc3066en
dc.publisher.departmentDepartment of Health and Rehabilitation Sciencesen_US
dc.publisher.facultyFaculty of Health Sciencesen_US
dc.rights.holderThe Author(s)
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceBMC Infectious Diseasesen_US
dc.source.journalissueArticle number: 859en_US
dc.source.journalvolume21en_US
dc.source.urihttps://bmcinfectdis.biomedcentral.com/
dc.subjectHIVen_US
dc.subjectAntiretroviral therapyen_US
dc.subjectCell phoneen_US
dc.subjectText-messageen_US
dc.subjectMedication adherenceen_US
dc.subjectPhysical exercise adherenceen_US
dc.subjectQuality of lifeen_US
dc.titleEffectiveness of mobile text reminder in improving adherence to medication, physical exercise, and quality of life in patients living with HIV: a systematic reviewen_US
dc.typeJournal Articleen_US
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