Trends in maternal and neonatal mortality in South Africa: a systematic review

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dc.contributor.authorDamian, Damian J
dc.contributor.authorNjau, Bernard
dc.contributor.authorLisasi, Ester
dc.contributor.authorMsuya, Sia E
dc.contributor.authorBoulle, Andrew
dc.date.accessioned2019-04-12T12:20:59Z
dc.date.available2019-04-12T12:20:59Z
dc.date.issued2019-03-27
dc.date.updated2019-03-31T03:14:47Z
dc.description.abstractBackground Measuring and monitoring progress towards Millennium Development Goals (MDG) 4 and 5 required valid and reliable estimates of maternal and child mortality. In South Africa, there are conflicting reports on the estimates of maternal and neonatal mortality, derived from both direct and indirect estimation techniques. This study aimed to systematically review the estimates made of maternal and neonatal mortality in the period from 1990 to 2015 in South Africa and determine trends over this period. Methods Nationally-representative studies reporting on maternal and neonatal mortality in South Africa were included for synthesis. Literature search for eligible studies was conducted in five electronic databases: Medline, Africa-Wide Information, Scopus, Web of Science and CINAHL. Searches were restricted to articles written in English and presenting data covering the period between 1990 and 2015. Reference lists of retrieved articles were screened for additional publications, and grey literature was searched for relevant documents for the review. Three independent reviewers were involved in study selection, data extractions and achieving consensus. Results In total, 969 studies were retrieved and 670 screened for eligibility yielding 25 studies reporting data on maternal mortality and 14 studies on neonatal mortality. Most of the studies had a low risk of bias. Estimates from the institutional reporting differed from the international metrics with wide uncertainty/confidence intervals. Moreover, modelled estimates were widely divergent from estimates obtained through empirical methods. In the last two decades, both maternal and neonatal mortality appear to have increased up to 2009, followed by a decrease, more pronounced in the care of maternal mortality. Conclusion Estimates from both global metrics and institutional reporting, although widely divergent, indicate South Africa has not achieved MDG 4a and 5a goals but made a significant progress in reducing maternal and neonatal mortality. To obtain more accurate estimates, there is a need for applying additional estimation techniques which utilise available multiple data sources to correct for underreporting of these outcomes, perhaps the capture-recapture method. Systematic review registration PROSPERO CRD42016042769
dc.identifier.apacitationDamian, D. J., Njau, B., Lisasi, E., Msuya, S. E., & Boulle, A. (2019). Trends in maternal and neonatal mortality in South Africa: a systematic review. <i>Systematic Reviews</i>, http://hdl.handle.net/11427/29968en_ZA
dc.identifier.chicagocitationDamian, Damian J, Bernard Njau, Ester Lisasi, Sia E Msuya, and Andrew Boulle "Trends in maternal and neonatal mortality in South Africa: a systematic review." <i>Systematic Reviews</i> (2019) http://hdl.handle.net/11427/29968en_ZA
dc.identifier.citationDamian, D. J., Njau, B., Lisasi, E., Msuya, S. E., & Boulle, A. (2019). Trends in maternal and neonatal mortality in South Africa: a systematic review. Systematic reviews, 8(1), 76.
dc.identifier.ris TY - Journal Article AU - Damian, Damian J AU - Njau, Bernard AU - Lisasi, Ester AU - Msuya, Sia E AU - Boulle, Andrew AB - Background Measuring and monitoring progress towards Millennium Development Goals (MDG) 4 and 5 required valid and reliable estimates of maternal and child mortality. In South Africa, there are conflicting reports on the estimates of maternal and neonatal mortality, derived from both direct and indirect estimation techniques. This study aimed to systematically review the estimates made of maternal and neonatal mortality in the period from 1990 to 2015 in South Africa and determine trends over this period. Methods Nationally-representative studies reporting on maternal and neonatal mortality in South Africa were included for synthesis. Literature search for eligible studies was conducted in five electronic databases: Medline, Africa-Wide Information, Scopus, Web of Science and CINAHL. Searches were restricted to articles written in English and presenting data covering the period between 1990 and 2015. Reference lists of retrieved articles were screened for additional publications, and grey literature was searched for relevant documents for the review. Three independent reviewers were involved in study selection, data extractions and achieving consensus. Results In total, 969 studies were retrieved and 670 screened for eligibility yielding 25 studies reporting data on maternal mortality and 14 studies on neonatal mortality. Most of the studies had a low risk of bias. Estimates from the institutional reporting differed from the international metrics with wide uncertainty/confidence intervals. Moreover, modelled estimates were widely divergent from estimates obtained through empirical methods. In the last two decades, both maternal and neonatal mortality appear to have increased up to 2009, followed by a decrease, more pronounced in the care of maternal mortality. Conclusion Estimates from both global metrics and institutional reporting, although widely divergent, indicate South Africa has not achieved MDG 4a and 5a goals but made a significant progress in reducing maternal and neonatal mortality. To obtain more accurate estimates, there is a need for applying additional estimation techniques which utilise available multiple data sources to correct for underreporting of these outcomes, perhaps the capture-recapture method. Systematic review registration PROSPERO CRD42016042769 DA - 2019-03-27 DB - OpenUCT DP - University of Cape Town J1 - Systematic Reviews LK - https://open.uct.ac.za PY - 2019 T1 - Trends in maternal and neonatal mortality in South Africa: a systematic review TI - Trends in maternal and neonatal mortality in South Africa: a systematic review UR - http://hdl.handle.net/11427/29968 ER - en_ZA
dc.identifier.urihttps://doi.org/10.1186/s13643-019-0991-y
dc.identifier.urihttp://hdl.handle.net/11427/29968
dc.identifier.vancouvercitationDamian DJ, Njau B, Lisasi E, Msuya SE, Boulle A. Trends in maternal and neonatal mortality in South Africa: a systematic review. Systematic Reviews. 2019; http://hdl.handle.net/11427/29968.en_ZA
dc.language.rfc3066en
dc.rights.holderThe Author(s).
dc.sourceSystematic Reviews
dc.source.urihttps://systematicreviewsjournal.biomedcentral.com/
dc.titleTrends in maternal and neonatal mortality in South Africa: a systematic review
dc.typeJournal Article
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