Withdrawal of parenteral phenobarbitone - implications for resource-poor countries
| dc.contributor.author | Wilmshurst, J M | |
| dc.contributor.author | Van Toorn, Ronald | |
| dc.contributor.author | Newton, C R J C | |
| dc.date.accessioned | 2018-03-13T08:49:35Z | |
| dc.date.available | 2018-03-13T08:49:35Z | |
| dc.date.issued | 2005 | |
| dc.date.updated | 2016-01-16T06:40:47Z | |
| dc.description.abstract | Parenteral phenobarbitone is an integral part of the management of status epilepticus, especially in the context of resource-poor countries. It is highly effective at controlling seizures. It is safe, cheap, can be given by rapid intravenous push or intramuscular route, boluses can be repeated, and it is recommended as part of the Advanced Paediatric Life Support guidelines. The proposed alternatives lack efficacy, practicality and/or place the child in status epilepticus at risk of respiratory compromise. The impact of the loss of parenteral phenobarbitone would be increased cardiac complications, lack of early seizure control, prolonged seizures resulting in brain damage and systemic complications. Increased numbers of patients will require artificial ventilation in centres without facilities, and centres with facilities will be unable to cope with the load of ventilated patients because of lack of safe transport systems and bed space. | |
| dc.identifier.apacitation | Wilmshurst, J. M., Van Toorn, R., & Newton, C. R. J. C. (2005). Withdrawal of parenteral phenobarbitone - implications for resource-poor countries. <i>South African Medical Journal</i>, http://hdl.handle.net/11427/27641 | en_ZA |
| dc.identifier.chicagocitation | Wilmshurst, J M, Ronald Van Toorn, and C R J C Newton "Withdrawal of parenteral phenobarbitone - implications for resource-poor countries." <i>South African Medical Journal</i> (2005) http://hdl.handle.net/11427/27641 | en_ZA |
| dc.identifier.citation | Wilmshurst, J. M., Van Toorn, R., & Newton, C. R. J. C. (2005). Withdrawal of parenteral phenobarbitone-implications for resource-poor countries: original article. South African Medical Journal, 95(6), p-422. | |
| dc.identifier.ris | TY - Journal Article AU - Wilmshurst, J M AU - Van Toorn, Ronald AU - Newton, C R J C AB - Parenteral phenobarbitone is an integral part of the management of status epilepticus, especially in the context of resource-poor countries. It is highly effective at controlling seizures. It is safe, cheap, can be given by rapid intravenous push or intramuscular route, boluses can be repeated, and it is recommended as part of the Advanced Paediatric Life Support guidelines. The proposed alternatives lack efficacy, practicality and/or place the child in status epilepticus at risk of respiratory compromise. The impact of the loss of parenteral phenobarbitone would be increased cardiac complications, lack of early seizure control, prolonged seizures resulting in brain damage and systemic complications. Increased numbers of patients will require artificial ventilation in centres without facilities, and centres with facilities will be unable to cope with the load of ventilated patients because of lack of safe transport systems and bed space. DA - 2005 DB - OpenUCT DP - University of Cape Town J1 - South African Medical Journal LK - https://open.uct.ac.za PB - University of Cape Town PY - 2005 T1 - Withdrawal of parenteral phenobarbitone - implications for resource-poor countries TI - Withdrawal of parenteral phenobarbitone - implications for resource-poor countries UR - http://hdl.handle.net/11427/27641 ER - | en_ZA |
| dc.identifier.uri | http://hdl.handle.net/11427/27641 | |
| dc.identifier.vancouvercitation | Wilmshurst JM, Van Toorn R, Newton CRJC. Withdrawal of parenteral phenobarbitone - implications for resource-poor countries. South African Medical Journal. 2005; http://hdl.handle.net/11427/27641. | en_ZA |
| dc.language.iso | eng | |
| dc.publisher.department | Department of Paediatrics and Child Health | en_ZA |
| dc.publisher.faculty | Faculty of Health Sciences | en_ZA |
| dc.publisher.institution | University of Cape Town | |
| dc.source | South African Medical Journal | |
| dc.source.uri | http://www.samj.org.za | |
| dc.subject.other | Parenteral phenobarbitone | |
| dc.subject.other | Withdrawal Resource-poor countries | |
| dc.subject.other | Implications | |
| dc.title | Withdrawal of parenteral phenobarbitone - implications for resource-poor countries | |
| dc.type | Journal Article | |
| uct.type.filetype | Text |